Galanthamine hydrobromide, Alkaloid acetylcholinesterase inhibitor (ab141114)

Overview

  • Product name

    Galanthamine hydrobromide, Alkaloid acetylcholinesterase inhibitor
  • Description

    Alkaloid acetylcholinesterase inhibitor
  • Alternative names

    • Galantamine
  • Biological description

    Alkaloid acetylcholinesterase inhibitor (IC50 values are 0.85 and 12.1 μM for AChE and butyrylcholinesterase, respectively). Blood-brain barrier permeable. Active in vivo following oral administration. Prevents beta-amyloid induced apotosis. Reduces neurodegeneration in vivo.
  • Purity

    > 99%
  • CAS Number

    1953-04-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Arias E  et al. Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors. Neuropharmacology 46:103-14 (2004). Read more (PubMed: 14654102) »
  • Capsoni S  et al. Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice. Proc Natl Acad Sci U S A 99:12432-7 (2002). Read more (PubMed: 12205295) »
  • Sramek JJ  et al. Review of the acetylcholinesterase inhibitor galanthamine. Expert Opin Investig Drugs 9:2393-402 (2000). Read more (PubMed: 11060814) »
  • Sweeney JE  et al. Galanthamine, an acetylcholinesterase inhibitor: a time course of the effects on performance and neurochemical parameters in mice. Pharmacol Biochem Behav 34:129-37 (1989). Read more (PubMed: 2626444) »
See 1 Publication for this product

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