• Product name

    Anti-GALE antibody [EPR11088(B)]
    See all GALE primary antibodies
  • Description

    Rabbit monoclonal [EPR11088(B)] to GALE
  • Host species

  • Tested applications

    Suitable for: WB, Flow Cyt, IPmore details
    Unsuitable for: ICC or IHC-P
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human GALE (UniProt Q14376).

  • Positive control

    • HepG2, A375, MCF7 and HeLa cell lysates; Hela cells.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.



Our Abpromise guarantee covers the use of ab155997 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/50000. Predicted molecular weight: 38 kDa.
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.


IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for ICC or IHC-P.
  • Target

    • Function

      Catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine.
    • Pathway

      Carbohydrate metabolism; galactose metabolism.
    • Involvement in disease

      Defects in GALE are the cause of epimerase-deficiency galactosemia (EDG) [MIM:230350]; also known as galactosemia type 3. Clinical features include early-onset cataracts, liver damage, deafness and mental retardation. There are two clinically distinct forms of EDG. (1) A benign, or 'peripheral' form with no detectable GALE activity in red blood cells and characterized by mild symptoms. Some patients may suffer no symptoms beyond raised levels of galactose-1-phosphate in the blood. (2) A much rarer 'generalized' form with undetectable levels of GALE activity in all tissues and resulting in severe features such as restricted growth and mental development.
    • Sequence similarities

      Belongs to the sugar epimerase family.
    • Information by UniProt
    • Database links

    • Alternative names

      • FLJ95174 antibody
      • FLJ97302 antibody
      • Galactose 4 epimerase UDP antibody
      • Galactowaldenase antibody
      • galE antibody
      • GALE_HUMAN antibody
      • OTTHUMP00000002991 antibody
      • OTTHUMP00000002994 antibody
      • OTTHUMP00000037931 antibody
      • OTTHUMP00000044857 antibody
      • SDR1E1 antibody
      • short chain dehydrogenase/reductase family 1E member 1 antibody
      • UDP galactose 4 epimerase antibody
      • UDP galactose 4' epimerase antibody
      • UDP glucose 4 epimerase antibody
      • UDP-galactose 4-epimerase antibody
      • UDP-glucose 4-epimerase antibody
      see all


    • All lanes : Anti-GALE antibody [EPR11088(B)] (ab155997) at 1/10000 dilution

      Lane 1 : HepG2 cell lysate
      Lane 2 : A375 cell lysate
      Lane 3 : MCF7 cell lysate
      Lane 4 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.

      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 38 kDa

    • Flow cytometric analysis of permeabilized HeLa cells labeling GALE with ab155997 at 1/10 dilution (red) compared to a rabbit IgG negative control (green).


    This product has been referenced in:

    • Andres LM  et al. Chemical Modulation of Protein O-GlcNAcylation via OGT Inhibition Promotes Human Neural Cell Differentiation. ACS Chem Biol 12:2030-2039 (2017). Read more (PubMed: 28541657) »
    • Zhu Y  et al. Hepatic GALE Regulates Whole-Body Glucose Homeostasis by Modulating Tff3 Expression. Diabetes 66:2789-2799 (2017). Read more (PubMed: 28877911) »
    See all 2 Publications for this product

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