Recombinant
RabMAb

Recombinant Anti-Galectin 1 antibody [EPR3205] - Low endotoxin, Azide free (ab225540)

Overview

  • Product name

    Anti-Galectin 1 antibody [EPR3205] - Low endotoxin, Azide free
    See all Galectin 1 primary antibodies
  • Description

    Rabbit monoclonal [EPR3205] to Galectin 1 - Low endotoxin, Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IP, IHC-FoFrmore details
    Unsuitable for: IHC-P
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human Galectin 1

  • Positive control

    • HL60 cell lysate, K562 cell lysate, NIH 3T3 cell lysate, mouse heart tissue lysate, mouse kidney cell lysate, mouse spleen cell lysate, rat heart tissue lysate, rat kidney tissue lysate.
  • General notes

    ab225540 is a carrier-free antibody designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our Low endotoxin, azide-free formats have low endotoxin level (≤ 1 EU/ml, determined by the LAL assay) and are free from azide, to achieve consistent experimental results in functional assays.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab225540 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 15 kDa.
IP Use at an assay dependent concentration.
IHC-FoFr Use at an assay dependent concentration. PubMed: 23682281
  • Application notes
    Is unsuitable for IHC-P.
  • Target

    • Function

      May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.
    • Tissue specificity

      Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.
    • Sequence similarities

      Contains 1 galectin domain.
    • Cellular localization

      Secreted > extracellular space > extracellular matrix.
    • Information by UniProt
    • Database links

    • Alternative names

      • 14 kDa laminin-binding protein antibody
      • 14 kDa lectin antibody
      • Beta galactoside binding lectin antibody
      • Beta galactoside binding lectin L 14 I antibody
      • beta galactoside binding protein antibody
      • Beta-galactoside-binding lectin L-14-I antibody
      • DKFZp686E23103 antibody
      • Gal 1 antibody
      • Gal-1 antibody
      • GAL1 antibody
      • Galaptin antibody
      • Galbp antibody
      • Galectin antibody
      • Galectin-1 antibody
      • Galectin1 antibody
      • GBP antibody
      • HBL antibody
      • HLBP14 antibody
      • HPL antibody
      • L 14.5 antibody
      • L-14.5 antibody
      • L14 antibody
      • Lactose binding lectin 1 antibody
      • Lactose-binding lectin 1 antibody
      • Lect14 antibody
      • Lectin galactoside binding soluble 1 antibody
      • Lectin galactoside-binding soluble 1 antibody
      • LEG1_HUMAN antibody
      • LGALS 1 antibody
      • LGALS1 antibody
      • Lgals1 lectin galactose binding soluble 1 antibody
      • MAPK activating protein MP12 antibody
      • Putative MAPK activating protein MP12 antibody
      • Putative MAPK-activating protein PM12 antibody
      • S Lac lectin 1 antibody
      • S-Lac lectin 1 antibody
      see all

    References

    This product has been referenced in:

    • Pereira PM  et al. Galactodendritic phthalocyanine targets carbohydrate-binding proteins enhancing photodynamic therapy. PLoS One 9:e95529 (2014). WB, ICC/IF ; Human . Read more (PubMed: 24763311) »
    • Gurel Z  et al. Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy. PLoS One 9:e95561 (2014). WB ; Mouse . Read more (PubMed: 24788674) »
    See all 4 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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