Overview

  • Product name

  • Description

    Rabbit polyclonal to GALK1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Cow, Dog
  • Immunogen

    Recombinant fragment (internal sequence). The exact sequence is proprietary.
    Database link: P51570

  • Positive control

    • WB: HepG2 whole cell lysate. ICC/IF: HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab228533 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 42 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function

    Major enzyme for galactose metabolism.
  • Pathway

    Carbohydrate metabolism; galactose metabolism.
  • Involvement in disease

    Defects in GALK1 are the cause of galactosemia II (GALCT2) [MIM:230200]. Galactosemia II is an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses.
  • Sequence similarities

    Belongs to the GHMP kinase family. GalK subfamily.
  • Information by UniProt
  • Database links

  • Alternative names

    • EC 2.7.1.6 antibody
    • epididymis secretory protein Li 19 antibody
    • Galactokinase 1 antibody
    • Galactokinase antibody
    • Galactose kinase antibody
    • GALK 1 antibody
    • GALK antibody
    • GALK1 antibody
    • GALK1_HUMAN antibody
    • GK1 antibody
    • GLK antibody
    • GLK1 antibody
    • HEL-S-19 antibody
    see all

Images

  • Anti-GALK1 antibody (ab228533) at 1/2000 dilution + HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate at 30 µg

    Developed using the ECL technique.

    Predicted band size: 42 kDa



    10% SDS-PAGE

  • HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for GALK1 (green) using ab228533 at 1:500 dilution in ICC/IF. Cells were fixed in 100% methanol for 5 minutes.

    Blue: Hoechst 33342 staining.

References

ab228533 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab228533.
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