Overview

  • Product name

    Anti-GALNS/Chondroitinase antibody
    See all GALNS/Chondroitinase primary antibodies
  • Description

    Rabbit polyclonal to GALNS/Chondroitinase
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog, Pig
  • Immunogen

    Recombinant fragment corresponding to Human GALNS/Chondroitinase aa 20-269.
    Database link: NP_000503

  • Positive control

    • 293T, A431, H1299, HeLa, HepG2, MOLT4 and Raji whole cell lysates; NCI-N87 xenograft tissue.
  • General notes

     This product was previously labelled as GALNS

     

Properties

Applications

Our Abpromise guarantee covers the use of ab97913 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 58 kDa.
IHC-P 1/100 - 1/500.

Target

  • Relevance

    GALNS (N-acetylgalactosamine-6-sulfatase) is a lysosomal exohydrolase which catalyzes the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.
  • Cellular localization

    Lysosome
  • Database links

  • Alternative names

    • Chondroitinase antibody
    • Chondroitinsulfatase antibody
    • FLJ00319 antibody
    • FLJ17434 antibody
    • FLJ42844 antibody
    • FLJ98217 antibody
    • Galactosamine (N acetyl) 6 sulfate sulfatase antibody
    • Galactose 6 sulfate sulfatase antibody
    • GALNAC6S antibody
    • GalNAc6S sulfatase antibody
    • GALNS6 antibody
    • GAS antibody
    • mFLJ00319 antibody
    • MPS4A antibody
    • N acetylgalactosamine 6 sulfatase antibody
    • N acetylgalactosamine 6 sulfate sulfatase antibody
    see all

Images

  • Anti-GALNS/Chondroitinase antibody (ab97913) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size: 58 kDa



    7.5% SDS-PAGE.
  • ab97913 at 1/100 dilution staining GALNS/Chondroitinase in NCI-N87 xenograft by Immunohistochemistry, Paraffin-embedded tissue.

References

This product has been referenced in:

  • Luo M  et al. Changes in the metabolism of chondroitin sulfate glycosaminoglycans in articular cartilage from patients with Kashin-Beck disease. Osteoarthritis Cartilage 22:986-95 (2014). Read more (PubMed: 24857976) »
See 1 Publication for this product

Customer reviews and Q&As

Application
Immunohistochemistry (Frozen sections)
Sample
Bos taurus Tissue sections (uterus)
Permeabilization
No
Specification
uterus
Blocking step
Serum as blocking agent for 30 minute(s) · Concentration: 2% · Temperature: 25°C
Fixative
Acetone

Abcam user community

Verified customer

Submitted Feb 10 2017

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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