Overview

  • Product name

  • Description

    Rabbit polyclonal to GALR2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human GALR2 aa 82-99 conjugated to Keyhole Limpet Haemocyanin (KLH).
    Sequence:

    QATIYTLDGWVFGSLLCK


    Database link: O43603

  • Positive control

    • Rat brain tissue and Mouse brain lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab203072 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

(or 1/50 - 1/200 using a fluorescent secondary antibody)

WB 1/100 - 1/1000. Predicted molecular weight: 42 kDa.

Target

  • Function

    Receptor for the hormone galanin and for GALP. The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)).
  • Tissue specificity

    Expressed abundantly within the central nervous system in both hypothalamus and hippocampus. In peripheral tissues, the strongest expression was observed in heart, kidney, liver, and small intestine.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • GAL2-R antibody
    • GAL2R antibody
    • Galanin receptor 2 antibody
    • Galanin receptor type 2 antibody
    • GALNR2 antibody
    • GALR-2 antibody
    • GALR2 antibody
    • GALR2_HUMAN antibody
    • MGC125983 antibody
    • MGC125984 antibody
    see all

Images

  • Anti-GALR2 antibody (ab203072) at 1/200 dilution (overnight at 4°C) + Mouse brain lysate

    Secondary
    HRP conjugated secondary antibody for 90 min at 37°C at 1/3000 dilution

    Predicted band size: 42 kDa
    Observed band size: 42 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Rat brain labeling GALR2 with ab203072 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

References

This product has been referenced in:

  • Zhang ML  et al. Involvement of galanin and galanin receptor 2 in nociceptive modulation in anterior cingulate cortex of normal rats and rats with mononeuropathy. Sci Rep 7:45930 (2017). Read more (PubMed: 28378856) »
See 1 Publication for this product

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