Product namegamma-Acetylenic GABA, GABA transaminase inhibitor
DescriptionIrreversible GABA transaminase inhibitor
- 4-Amino-5-hexynoic acid
- gamma-Acetylenic GABA
- RMI 71645
Irreversible GABA transaminase inhibitor. Inhibits Tetrapyrrole biosynthesis in plants.
Chemical name4-Amino-5-hexynoic acid
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 25 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Elich TD & Lagarias JC 4-amino-5-hexynoic Acid-a potent inhibitor of tetrapyrrole biosynthesis in plants. Plant Physiol 88:747-51 (1988). Read more (PubMed: 16666377) »
- Carney IT et al. A kinetic model for the action of the enzyme activated irreversible inhibitor 4-amino-5-hexynoic acid in vivo. Biochem Pharmacol 33:3765-9 (1984). Read more (PubMed: 6508832) »
- Abdul-Ghani AS et al. Effects of gamma-acetylenic GABA and gamma-vinyl GABA on synaptosomal release and uptake of GABA. Biochem Pharmacol 30:1203-9 (1981). Read more (PubMed: 7271818) »
- Abdul-Ghani AS et al. The action of gamma-vinyl-GABA and gamma-acetylenic-GABA on the resting and stimulated release of GABA in vivo. Brain Res 191:471-81 (1980). Read more (PubMed: 7378767) »