• Product name
    Anti-gamma Catenin (phospho Y550) antibody
    See all gamma Catenin primary antibodies
  • Description
    Rabbit polyclonal to gamma Catenin (phospho Y550)
  • Host species
  • Specificity
    ab29041 recognises gamma Catenin (phospho Y550).
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Phospho synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 550 of human gamma Catenin.

  • Positive control
    • A431 cells treated with pervanadate.


  • Form
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.05% Sodium azide
    Constituents: PBS, 50% Glycerol, 0.1% BSA
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab29041 was cross adsorbed to both phospho tyrosine coupled to agarose and to dephosphorylated gamma Catenin (Tyr550) peptide before immunogen affinity purification (without carrier protein).
  • Clonality
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab29041 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notes
    ELISA: 1/2000.
    WB: 1/1000 in 5% non fat milk, PBS, 0.04% Tween 20 for 1hour at room temperature. Predicted molecular weight: 80 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
    • Involvement in disease
      Defects in JUP are the cause of Naxos disease (NXD) [MIM:601214]. NXD is an autosomal recessive disorder combining diffuse non-epidermolytic palmoplantar keratoderma with arrhythmogenic right ventricular dysplasia/cardiomyopathy and woolly hair.
      Defects in JUP are the cause of familial arrhythmogenic right ventricular dysplasia type 12 (ARVD12) [MIM:611528]; also called arrhythmogenic right ventricular cardiomyopathy 12 (ARVC12). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.
    • Sequence similarities
      Belongs to the beta-catenin family.
      Contains 9 ARM repeats.
    • Cellular localization
      Cell junction > adherens junction. Cell junction > desmosome. Cytoplasm > cytoskeleton. Membrane. Cytoplasmic in a soluble and membrane-associated form.
    • Information by UniProt
    • Database links
    • Alternative names
      • ARVD 12 antibody
      • ARVD12 antibody
      • Catenin (cadherin associated protein), gamma 80kDa antibody
      • catenin (cadherin-associated protein) gamma (80kD) antibody
      • Catenin gamma antibody
      • CTNNG antibody
      • Desmoplakin 3 antibody
      • Desmoplakin III antibody
      • Desmoplakin-3 antibody
      • Desmoplakin3 antibody
      • DesmoplakinIII antibody
      • DP 3 antibody
      • DP III antibody
      • DP3 antibody
      • DPIII antibody
      • gamma catenin antibody
      • Junction plakoglobin antibody
      • JUP antibody
      • OTTHUMP00000164732 antibody
      • OTTHUMP00000164735 antibody
      • OTTHUMP00000164738 antibody
      • PDGB antibody
      • PKGB antibody
      • PLAK_HUMAN antibody
      • PLAKOGLOBIN antibody
      see all


    • Western blot analysis of gamma-Catenin immunoprecipitated from lysates prepared from A431 cells treated with pervanadate. The immunoprecipitation was performed using mouse monoclonal anti-gamma-Catenin. The blots were probed with anti-phospho-gamma-Catenin (Tyr-550) antibody. The immunoprecipitated gamma-Catenin was untreated (lane 1) or treated with alkaline phosphatase (lane 2) then probed with the antibody. In addition, the anti-phospho-gamma-Catenin (Tyr-550) was used in the presence of phospho-gamma-Catenin (Tyr-550) peptide (lane 3) or phospho-gamma-Catenin (Tyr-644) peptide (lane 4).


    ab29041 has not yet been referenced specifically in any publications.

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