Overview

  • Product name

    gamma-Linolenic acid, Unsaturated fatty acid
  • Description

    Unsaturated fatty acid
  • Biological description

    Unsaturated fatty acid. Putative anticancer agent. Linoleic acid (ab141144) derivative. Induces ROS generation. Inactivates NFκB. May also act via peroxisome proliferator activated receptors (PPARs) by stimulating their phosphorylation and translocation to the nucleus. Shows anti-inflammatory and antihypertensive effects in vivo. Orally active.
  • CAS Number

    506-26-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Park JH  et al. Gamma-linolenic acid inhibits hepatic PAI-1 expression by inhibiting p38 MAPK-dependent activator protein and mitochondria-mediated apoptosis pathway. Apoptosis : (2014). Read more (PubMed: 25534317) »
  • Kapoor R & Huang YS Gamma linolenic acid: an antiinflammatory omega-6 fatty acid. Curr Pharm Biotechnol 7:531-4 (2006). Read more (PubMed: 17168669) »
  • Engler MM  et al. Effects of dietary gamma-linolenic acid on blood pressure and adrenal angiotensin receptors in hypertensive rats. Proc Soc Exp Biol Med 218:234-7 (1998). Read more (PubMed: 9648942) »

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