Overview

  • Product name

  • Description

    Rabbit polyclonal to GAMT
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human GAMT (internal sequence). The exact sequence is proprietary.
    Database link: Q14353

  • Positive control

    • WB: HepG2 whole cell extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab228629 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 26 kDa.

Target

  • Tissue specificity

    Expressed in liver.
  • Pathway

    Amine and polyamine biosynthesis; creatine biosynthesis; creatine from L-arginine and glycine: step 2/2.
  • Involvement in disease

    Defects in GAMT are the cause of guanidinoacetate methyltransferase deficiency (GAMT deficiency) [MIM:612736]. GAMT deficiency is an autosomal recessive disorder characterized by developmental delay/regression, mental retardation, severe disturbance of expressive and cognitive speech, intractable seizures and movement disturbances, severe depletion of creatine/phosphocreatine in the brain, and accumulation of guanidinoacetic acid (GAA) in brain and body fluids.
  • Sequence similarities

    Belongs to the RMT2 methyltransferase family.
  • Information by UniProt
  • Database links

  • Alternative names

    • CCDS2 antibody
    • Epididymis secretory protein Li 20 antibody
    • GAMT antibody
    • GAMT_HUMAN antibody
    • Guanidinoacetate N methyltransferase antibody
    • Guanidinoacetate N-methyltransferase antibody
    • HEL-S-20 antibody
    • PIG2 antibody
    • TP53I2 antibody
    see all

Images

  • Anti-GAMT antibody (ab228629) at 1/500 dilution + HepG2 (human liver hepatocellular carcinoma cell line) whole cell extract at 30 µg

    Developed using the ECL technique.

    Predicted band size: 26 kDa



    12% SDS-PAGE

References

ab228629 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab228629.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up