Overview

  • Product name

    Anti-GAMT antibody [EPR6924]
    See all GAMT primary antibodies
  • Description

    Rabbit monoclonal [EPR6924] to GAMT
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human GAMT aa 50-150. The exact sequence is proprietary.

  • Positive control

    • HepG2 cell lysate, SH SY5Y cell lysate, Human fetal liver lysate.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab128918 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 26 kDa (predicted molecular weight: 26 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Tissue specificity

      Expressed in liver.
    • Pathway

      Amine and polyamine biosynthesis; creatine biosynthesis; creatine from L-arginine and glycine: step 2/2.
    • Involvement in disease

      Defects in GAMT are the cause of guanidinoacetate methyltransferase deficiency (GAMT deficiency) [MIM:612736]. GAMT deficiency is an autosomal recessive disorder characterized by developmental delay/regression, mental retardation, severe disturbance of expressive and cognitive speech, intractable seizures and movement disturbances, severe depletion of creatine/phosphocreatine in the brain, and accumulation of guanidinoacetic acid (GAA) in brain and body fluids.
    • Sequence similarities

      Belongs to the RMT2 methyltransferase family.
    • Information by UniProt
    • Database links

    • Alternative names

      • CCDS2 antibody
      • Epididymis secretory protein Li 20 antibody
      • GAMT antibody
      • GAMT_HUMAN antibody
      • Guanidinoacetate N methyltransferase antibody
      • Guanidinoacetate N-methyltransferase antibody
      • HEL-S-20 antibody
      • PIG2 antibody
      • TP53I2 antibody
      see all

    Images

    • All lanes : Anti-GAMT antibody [EPR6924] (ab128918) at 1/1000 dilution

      Lane 1 : HepG2 cell lysate
      Lane 2 : SH SY5Y cell lysate
      Lane 3 : Human fetal liver lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 26 kDa
      Observed band size: 26 kDa

    References

    ab128918 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab128918.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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