Product nameAnti-Ganglioside GD2 antibody [14.G2a]
See all Ganglioside GD2 primary antibodies
DescriptionMouse monoclonal [14.G2a] to Ganglioside GD2
Tested applicationsSuitable for: ICC, IHC-Fr, Flow Cyt, ICC/IFmore details
Species reactivityReacts with: Human
This product was changed from ascites to tissue culture supernatant on 30/Aug/19. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1.45% Sodium chloride
Concentration information loading...
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab68456 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC||Use at an assay dependent concentration.|
|IHC-Fr||Use at an assay dependent concentration.|
|Flow Cyt||Use 1-2µg for 106 cells.
ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
|ICC/IF||Use at an assay dependent concentration.|
RelevanceGangliosides are a group of galactose-containing cerebrosides found in the surface membranes of nerve cells. Ganglioside GD2 is a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues, principally to the cerebellum and peripheral nerves in humans. GD2 is a suitable target for immunotherapy with monoclonal antibodies or with artificial T cell receptors due to its relatively tumor specific expression.
- Disialoganglioside GD2 antibody
This product has been referenced in:
- Tsujimoto T et al. An acellular bioresorbable ultra-purified alginate gel promotes intervertebral disc repair: A preclinical proof-of-concept study. EBioMedicine 37:521-534 (2018). Read more (PubMed: 30389504) »
- Feng X et al. Expression of EMT markers and mode of surgery are prognostic in phyllodes tumors of the breast. Oncotarget 8:33365-33374 (2017). Read more (PubMed: 28380418) »