Key features and details
- Rabbit polyclonal to Ganglioside GM1
- Suitable for: ICC/IF, ELISA, Thin Layer Chromatography
- Isotype: IgG
Product nameAnti-Ganglioside GM1 antibody
See all Ganglioside GM1 primary antibodies
DescriptionRabbit polyclonal to Ganglioside GM1
SpecificityRecognizes ganglioside GM1. Expresses some reactivity to asialo GM1 due to the natural background in rabbit. Does not crossreact with other carbohydrate epitopes.
Tested applicationsSuitable for: ICC/IF, ELISA, Thin Layer Chromatographymore details
Other Immunogen Type corresponding to Cow Ganglioside GM1. Immunogen=Purified monosialoganglioside GM1 and complete Freund’s adjuvant.
General notesAddition of glycerol as a cryopreservative is not recommended.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferConstituent: Whole serum
Concentration information loading...
Our Abpromise guarantee covers the use of ab31119 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use at an assay dependent concentration.|
|Thin Layer Chromatography||1/1000.|
RelevanceA member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system (CNS). It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorilation and synaptic function.
Cellular localizationPlasma membrane
- GM1 ganglioside antibody
- Monosialoanglioside antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab31119 has been referenced in 1 publication.
- Liang YJ et al. Changes in glycosphingolipid composition during differentiation of human embryonic stem cells to ectodermal or endodermal lineages. Stem Cells 29:1995-2004 (2011). PubMed: 21956927