Key features and details
- Downstream Hh signaling inhibitor
- CAS Number: 64048-12-0
- Purity: > 99%
- Soluble in DMSO to 25 mM (with warming) and in ethanol to 25 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Product nameGANT58, Hh signaling inhibitor
DescriptionDownstream Hh signaling inhibitor
Inhibits Hh signaling downstream of smo and sufu. IC50 = 5 μM for glioma associated oncogene expression in MEFs.
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 25 mM (with warming) and in ethanol to 25 mM (with warming)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Research Area
- Alzheimer's Disease
- Signal transduction
- Hedgehog signaling
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120665 has not yet been referenced specifically in any publications.