Product nameAnti-GAP43 antibody
See all GAP43 primary antibodies
DescriptionRabbit polyclonal to GAP43
SpecificityThis antibody recognises the protein designated Gap43.
Tested applicationsSuitable for: IHC-FoFr, IHC-Fr, IP, WB, ICC/IFmore details
Species reactivityReacts with: Mouse, Rat, Cat, Human, Monkey
Purified GAP43 from cat brain.
General notesThis product should be stored undiluted. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium Azide
Our Abpromise guarantee covers the use of ab11136 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-FoFr||Use at an assay dependent concentration. PubMed: 25249946|
|IHC-Fr||Use at an assay dependent concentration.|
|IP||Use at an assay dependent concentration.|
|WB||1/500 - 1/1000. Detects a band of approximately 43-57 kDa (predicted molecular weight: 28.6 kDa).|
|ICC/IF||Use at an assay dependent concentration.|
FunctionThis protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.
Sequence similaritiesBelongs to the neuromodulin family.
Contains 1 IQ domain.
modificationsPhosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.
Cellular localizationCell membrane. Cell projection > growth cone membrane. Cell junction > synapse. Cytoplasmic surface of growth cone and synaptic plasma membranes.
- Information by UniProt
- Axonal membrane protein GAP 43 antibody
- Axonal membrane protein GAP-43 antibody
- B 50 antibody
This product has been referenced in:
- Dhillon RS et al. Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy. Acta Neuropathol Commun 4:89 (2016). IHC-Fr ; Rat . Read more (PubMed: 27552807) »
- Benitez SU et al. Synaptic plasticity and sensory-motor improvement following fibrin sealant dorsal root reimplantation and mononuclear cell therapy. Front Neuroanat 8:96 (2014). IHC-FoFr ; Rat . Read more (PubMed: 25249946) »