Overview

  • Product name

  • Description

    Rabbit polyclonal to GAP43
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Cow, Human
    Predicted to work with: Chimpanzee, Cynomolgus monkey
  • Immunogen

    Synthetic peptide:

    KEDPEADQEHA

    conjugated to KLH, corresponding to C terminal amino acids 216-226 of Rat GAP43

  • Positive control

    • Cow brain homogenates, Mixed neuron-glial cultures.

Properties

Applications

Our Abpromise guarantee covers the use of ab128005 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000 - 1/10000. Predicted molecular weight: 24 kDa.
ICC/IF 1/500 - 1/1000.

Target

  • Function

    This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.
  • Sequence similarities

    Belongs to the neuromodulin family.
    Contains 1 IQ domain.
  • Post-translational
    modifications

    Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.
  • Cellular localization

    Cell membrane. Cell projection > growth cone membrane. Cell junction > synapse. Cytoplasmic surface of growth cone and synaptic plasma membranes.
  • Information by UniProt
  • Database links

  • Alternative names

    • Axonal membrane protein GAP 43 antibody
    • Axonal membrane protein GAP-43 antibody
    • B 50 antibody
    • Calmodulin binding protein P 57 antibody
    • F1 antibody
    • GAP 43 antibody
    • GAP43 antibody
    • Growth Associated Protein 43 antibody
    • Growth-associated protein 43 antibody
    • Nerve Growth Related Peptide antibody
    • Nerve growth related peptide GAP43 antibody
    • NEUM_HUMAN antibody
    • Neural phosphoprotein B 50 antibody
    • Neural phosphoprotein B-50 antibody
    • Neuromodulin antibody
    • Neuron growth associated protein 43 antibody
    • PP46 antibody
    • Protein F1 antibody
    • QtrA-11580 antibody
    • QtrA-13071 antibody
    see all

Images

  • ab128005 at 1/500 dilution stains GAP43 (red) in mixed neuron-glial cultures; blue is DNA staining.

References

This product has been referenced in:

  • Alastrue-Agudo A  et al. FM19G11 and Ependymal Progenitor/Stem Cell Combinatory Treatment Enhances Neuronal Preservation and Oligodendrogenesis after Severe Spinal Cord Injury. Int J Mol Sci 19:N/A (2018). Read more (PubMed: 29315225) »
See 1 Publication for this product

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