Overview

  • Product name

  • Description

    Chicken polyclonal to GAP43
  • Host species

    Chicken
  • Tested applications

    Suitable for: IHC-P, ICC, WBmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    A synthetic peptide, conjugated to KLH, corresponding to a region within the C-terminal amino acids of Mouse GAP43.

Properties

Applications

Our Abpromise guarantee covers the use of ab134019 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1000 - 1/2000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC 1/1000 - 1/2000.
WB 1/2000 - 1/5000. Predicted molecular weight: 24 kDa.

Target

  • Function

    This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.
  • Sequence similarities

    Belongs to the neuromodulin family.
    Contains 1 IQ domain.
  • Post-translational
    modifications

    Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.
  • Cellular localization

    Cell membrane. Cell projection > growth cone membrane. Cell junction > synapse. Cytoplasmic surface of growth cone and synaptic plasma membranes.
  • Information by UniProt
  • Database links

  • Alternative names

    • Axonal membrane protein GAP 43 antibody
    • Axonal membrane protein GAP-43 antibody
    • B 50 antibody
    • Calmodulin binding protein P 57 antibody
    • F1 antibody
    • GAP 43 antibody
    • GAP43 antibody
    • Growth Associated Protein 43 antibody
    • Growth-associated protein 43 antibody
    • Nerve Growth Related Peptide antibody
    • Nerve growth related peptide GAP43 antibody
    • NEUM_HUMAN antibody
    • Neural phosphoprotein B 50 antibody
    • Neural phosphoprotein B-50 antibody
    • Neuromodulin antibody
    • Neuron growth associated protein 43 antibody
    • PP46 antibody
    • Protein F1 antibody
    • QtrA-11580 antibody
    • QtrA-13071 antibody
    see all

Images

  • Immunocytochemistry at a dilution of 1:5000 labeling GAP43 in cultured cortical neurons from a neonatal mouse brain. Hoeschst was used as nuclear counterstain (blue).

References

This product has been referenced in:

  • Armelin-Correa LM  et al. Nuclear compartmentalization of odorant receptor genes. Proc Natl Acad Sci U S A 111:2782-7 (2014). ICC/IF ; Mouse . Read more (PubMed: 24550308) »
See 1 Publication for this product

Customer reviews and Q&As

Application
Immunocytochemistry/ Immunofluorescence
Sample
Rat Cell (Pontine explants (neuronal))
Permeabilization
Yes - PBST
Specification
Pontine explants (neuronal)
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 20°C
Fixative
Paraformaldehyde

Ms. Joanne Falck

Verified customer

Submitted Jun 14 2018

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up