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ab8245 has been referenced in 1247 publications.

  • Xu G  et al. Histone deacetylase 3 is associated with gastric cancer cell growth via the miR-454-mediated targeting of CHD5. Int J Mol Med 41:155-163 (2018). PubMed: 29115379
  • Yamada Y  et al. Passenger strand of miR-145-3p acts as a tumor-suppressor by targeting MYO1B in head and neck squamous cell carcinoma. Int J Oncol 52:166-178 (2018). PubMed: 29115582
  • Leipnitz G  et al. Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I deficiency. Sci Rep 8:1165 (2018). WB ; Human . PubMed: 29348607
  • Mastrodonato A  et al. Olfactory memory is enhanced in mice exposed to extremely low-frequency electromagnetic fields via Wnt/ß-catenin dependent modulation of subventricular zone neurogenesis. Sci Rep 8:262 (2018). PubMed: 29321633
  • Ramesh S  et al. SIRT3 activator Honokiol attenuates ß-Amyloid by modulating amyloidogenic pathway. PLoS One 13:e0190350 (2018). PubMed: 29324783
  • Yao L  et al. MicroRNA-124 regulates the expression of MEKK3 in the inflammatory pathogenesis of Parkinson's disease. J Neuroinflammation 15:13 (2018). PubMed: 29329581
  • Williams JJL  et al. Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability. Nat Commun 9:168 (2018). PubMed: 29330478
  • Wang Y  et al. HOXD-AS1 promotes cell proliferation, migration and invasion through miR-608/FZD4 axis in ovarian cancer. Am J Cancer Res 8:170-182 (2018). PubMed: 29416930
  • You S  et al. An Aza resveratrol-chalcone derivative 6b protects mice against diabetic cardiomyopathy by alleviating inflammation and oxidative stress. J Cell Mol Med 22:1931-1943 (2018). PubMed: 29327811
  • Mira E  et al. SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2a. Nat Commun 9:575 (2018). WB . PubMed: 29422508
  • Yang HJ  et al. GP73 promotes invasion and metastasis of bladder cancer by regulating the epithelial-mesenchymal transition through the TGF-ß1/Smad2 signalling pathway. J Cell Mol Med 22:1650-1665 (2018). WB . PubMed: 29349903
  • Ma SJ  et al. Correlations ofEZH2andSMYD3gene polymorphisms with breast cancer susceptibility and prognosis. Biosci Rep 38:N/A (2018). WB . PubMed: 29089464
  • Liu S  et al. Gastrodin protects MC3T3-E1 osteoblasts from dexamethasone-induced cellular dysfunction and promotes bone formation via induction of the NRF2 signaling pathway. Int J Mol Med 41:2059-2069 (2018). PubMed: 29393365
  • Danziger O  et al. Interleukin-6 and Interferon-a SignalingviaJAK1-STAT Differentially Regulate Oncolytic versus Cytoprotective Antiviral States. Front Immunol 9:94 (2018). PubMed: 29441069
  • Gaude E  et al. NADH Shuttling Couples Cytosolic Reductive Carboxylation of Glutamine with Glycolysis in Cells with Mitochondrial Dysfunction. Mol Cell 69:581-593.e7 (2018). PubMed: 29452638
  • Yi F  et al. Overexpression of microRNA-506-3p aggravates the injury of vascular endothelial cells in patients with hypertension by downregulating Beclin1 expression. Exp Ther Med 15:2844-2850 (2018). PubMed: 29456688
  • Hong Y  et al. In vitro study on the role of SOX9 in trastuzumab resistance of adenocarcinoma of the esophagogastric junction. Exp Ther Med 15:3103-3107 (2018). PubMed: 29456713
  • Guo L  et al. 17ß-estradiol regulates the malignancy of cancer stem-like cells derived from the MCF7 cell line partially through Sox2. Oncol Lett 15:3790-3795 (2018). PubMed: 29467896
  • Zhao P & Zhang Z TNF-a promotes colon cancer cell migration and invasion by upregulating TROP-2. Oncol Lett 15:3820-3827 (2018). PubMed: 29467899
  • Zhang K  et al. PU.1/microRNA-142-3p targets ATG5/ATG16L1 to inactivate autophagy and sensitize hepatocellular carcinoma cells to sorafenib. Cell Death Dis 9:312 (2018). PubMed: 29472524
  • Kapadia B  et al. Fatty Acid Synthase induced S6Kinase facilitates USP11-eIF4B complex formation for sustained oncogenic translation in DLBCL. Nat Commun 9:829 (2018). PubMed: 29483509
  • Xie CJ  et al. Curcumin protects neural cells against ischemic injury in N2a cells and mouse brain with ischemic stroke. Brain Behav 8:e00921 (2018). PubMed: 29484272
  • Wu D  et al. Formononetin Administration Ameliorates Dextran Sulfate Sodium-Induced Acute Colitis by Inhibiting NLRP3 Inflammasome Signaling Pathway. Mediators Inflamm 2018:3048532 (2018). PubMed: 29507526
  • Yu X  et al. Baicalein induces cervical cancer apoptosis through the NF-?B signaling pathway. Mol Med Rep 17:5088-5094 (2018). PubMed: 29393414
  • Cervin J  et al. GM1 ganglioside-independent intoxication by Cholera toxin. PLoS Pathog 14:e1006862 (2018). PubMed: 29432456
  • Li PC  et al. Seawater inhalation induces acute lung injury via ROS generation and the endoplasmic reticulum stress pathway. Int J Mol Med 41:2505-2516 (2018). PubMed: 29436612
  • Wen G  et al. Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis. J Am Heart Assoc 7:N/A (2018). PubMed: 29437605
  • Shi J  et al. The response of nucleus pulposus cell senescence to static and dynamic compressions in a disc organ culture. Biosci Rep 38:N/A (2018). PubMed: 29437905
  • Zhang Z  et al. Resveratrol attenuates mechanical compression-induced nucleus pulposus cell apoptosis through regulating the ERK1/2 signaling pathway in a disc organ culture. Biosci Rep 38:N/A (2018). PubMed: 29439139
  • Fang H  et al. Osteogenic protein-1 attenuates apoptosis and enhances matrix synthesis of nucleus pulposus cells under high-magnitude compression though inhibiting the p38 MAPK pathway. Biosci Rep N/A:N/A (2018). PubMed: 29440560
  • Du Q  et al. Propofol inhibits proliferation, migration, and invasion but promotes apoptosis by regulation of Sox4 in endometrial cancer cells. Braz J Med Biol Res 51:e6803 (2018). PubMed: 29490000
  • Kavanagh Williamson M  et al. Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1. Viruses 10:N/A (2018). PubMed: 29518929
  • Yang X  et al. Thymosin a1 treatment reduces hepatic inflammation and inhibits hepatocyte apoptosis in rats with acute liver failure. Exp Ther Med 15:3231-3238 (2018). PubMed: 29545840
  • Yao Y  et al. MicroRNA-215 suppresses the proliferation, migration and invasion of non-small cell lung carcinoma cells through the downregulation of matrix metalloproteinase-16 expression. Exp Ther Med 15:3239-3246 (2018). PubMed: 29545841
  • Chen CCW  et al. Role of Parkin and endurance training on mitochondrial turnover in skeletal muscle. Skelet Muscle 8:10 (2018). PubMed: 29549884
  • Li F  et al. CEP55 promotes cell proliferation and inhibits apoptosis via the PI3K/Akt/p21 signaling pathway in human glioma U251 cells. Oncol Lett 15:4789-4796 (2018). PubMed: 29552118
  • Zhang J  et al. Effect of galectin-3 on vasculogenic mimicry in esophageal cancer cells. Oncol Lett 15:4907-4911 (2018). PubMed: 29552129
  • Zeng B  et al. SPP1 promotes ovarian cancer progression via Integrin ß1/FAK/AKT signaling pathway. Onco Targets Ther 11:1333-1343 (2018). PubMed: 29559792
  • Gao J  et al. HCN channels contribute to the sensitivity of intravenous anesthetics in developmental mice. Oncotarget 9:12907-12917 (2018). PubMed: 29560119
  • Tu J  et al. Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells. Stem Cell Res Ther 9:71 (2018). PubMed: 29562912
  • Zhang C  et al. MicroRNA-302a inhibits osteosarcoma cell migration and invasion by directly targeting IGF-1R. Oncol Lett 15:5577-5583 (2018). PubMed: 29563995
  • Wang X  et al. Cancer-associated fibroblasts induce epithelial-mesenchymal transition through secreted cytokines in endometrial cancer cells. Oncol Lett 15:5694-5702 (2018). PubMed: 29563996
  • Arribas Arranz J  et al. Suitability of Yin Yang 1 transcript and protein levels for biomarker studies in B cell non-Hodgkin lymphoma. Biomark Res 6:11 (2018). PubMed: 29564133
  • Yang Z  et al. miR-143-3p regulates cell proliferation and apoptosis by targeting IGF1R and IGFBP5 and regulating the Ras/p38 MAPK signaling pathway in rheumatoid arthritis. Exp Ther Med 15:3781-3790 (2018). PubMed: 29581736
  • Carmichael RE  et al. MEF2A regulates mGluR-dependent AMPA receptor trafficking independently of Arc/Arg3.1. Sci Rep 8:5263 (2018). PubMed: 29588465
  • Auger C  et al. Metformin adapts its cellular effects to bioenergetic status in a model of metabolic dysfunction. Sci Rep 8:5646 (2018). PubMed: 29618839
  • Abedini A  et al. RAGE binds preamyloid IAPP intermediates and mediates pancreatic ß cell proteotoxicity. J Clin Invest 128:682-698 (2018). PubMed: 29337308
  • Pi Z  et al. Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery. Mol Med Rep 17:6497-6505 (2018). PubMed: 29488606
  • Corrochano S  et al. A genetic modifier suggests that endurance exercise exacerbates Huntington's disease. Hum Mol Genet 27:1723-1731 (2018). PubMed: 29509900
  • Yu R  et al. miR-377 targets CUL4A and regulates metastatic capability in ovarian cancer. Int J Mol Med 41:3147-3156 (2018). PubMed: 29512715
  • Katigbak A  et al. Inducible Genome Editing with Conditional CRISPR/Cas9 Mice. G3 (Bethesda) 8:1627-1635 (2018). PubMed: 29519936
  • Guo W  et al. Up-regulated deubiquitinase USP4 plays an oncogenic role in melanoma. J Cell Mol Med 22:2944-2954 (2018). PubMed: 29542252
  • Zhou X  et al. MicroRNA-22 inhibits the proliferation and migration, and increases the cisplatin sensitivity, of osteosarcoma cells. Mol Med Rep 17:7209-7217 (2018). PubMed: 29568877
  • Fu X  et al. KIFC1, a novel potential prognostic factor and therapeutic target in hepatocellular carcinoma. Int J Oncol 52:1912-1922 (2018). PubMed: 29620256
  • Feist M  et al. Cooperative STAT/NF-?B signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression. Nat Commun 9:1514 (2018). PubMed: 29666362
  • Krysciak K  et al. Adaptation of motor unit contractile properties in rat medial gastrocnemius to treadmill endurance training: Relationship to muscle mitochondrial biogenesis. PLoS One 13:e0195704 (2018). PubMed: 29672614
  • Ladds MJGW  et al. Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenib. PLoS One 13:e0195956 (2018). PubMed: 29684045
  • Wang F & Sun Y Overexpression of Myosin Phosphatase Target Subunit 1 (MYPT1) Inhibits Tumor Progression and Metastasis of Gastric Cancer. Med Sci Monit 24:2508-2517 (2018). PubMed: 29687789
  • Kinsella S  et al. Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation. J Neuroinflammation 15:130 (2018). PubMed: 29720226
  • He Z  et al. MiR-422a regulates cellular metabolism and malignancy by targeting pyruvate dehydrogenase kinase 2 in gastric cancer. Cell Death Dis 9:505 (2018). PubMed: 29725130
  • Zhang Y  et al. miR-486-5p regulates the migration and invasion of colorectal cancer cells through targeting PIK3R1. Oncol Lett 15:7243-7248 (2018). PubMed: 29725442
  • Su L  et al. Leptin attenuates the growth of rabbit mesenchymal stem cells via the extracellular signal-regulated kinase signaling pathway. Exp Ther Med 15:4185-4190 (2018). PubMed: 29731817
  • Zhao H  et al. LIM and SH3 protein 1 knockdown suppresses proliferation and metastasis of colorectal carcinoma cells via inhibition of the mitogen-activated protein kinase signaling pathway. Oncol Lett 15:6839-6844 (2018). PubMed: 29731863
  • van den Heuvel CNAM  et al. Quantification and localization of oncogenic receptor tyrosine kinase variant transcripts using molecular inversion probes. Sci Rep 8:7072 (2018). PubMed: 29728634
  • Guan Y  et al. Effects of dexamethasone on C6 cell proliferation, migration and invasion through the upregulation of AQP1. Oncol Lett 15:7595-7602 (2018). PubMed: 29740485
  • Han YL  et al. Downregulation of microRNA-193-3p inhibits the progression of intrahepatic cholangiocarcinoma cells by upregulating TGFBR3. Exp Ther Med 15:4508-4514 (2018). PubMed: 29725386
  • Zhao D  et al. Identification of Glucose-Regulated Protein 78 (GRP78) as a Receptor in BHK-21 Cells for Duck Tembusu Virus Infection. Front Microbiol 9:694 (2018). PubMed: 29692766
  • Chen YH  et al. AGE/RAGE-Induced EMP Release via the NOX-Derived ROS Pathway. J Diabetes Res 2018:6823058 (2018). PubMed: 29744367
  • Zhou M  et al. Quantitative Proteomic Analysis Reveals Synaptic Dysfunction in the Amygdala of Rats Susceptible to Chronic Mild Stress. Neuroscience 376:24-39 (2018). WB . PubMed: 29452226
  • Chleilat E  et al. TGF-ß Signaling Regulates Development of Midbrain Dopaminergic and Hindbrain Serotonergic Neuron Subgroups. Neuroscience 381:124-137 (2018). WB ; Mouse . PubMed: 29689292
  • Yang L  et al. DNMT1/miR-200a/GOLM1 signaling pathway regulates lung adenocarcinoma cells proliferation. Biomed Pharmacother 99:839-847 (2018). WB . PubMed: 29710483
  • Puri C  et al. The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A. Dev Cell 45:114-131.e8 (2018). WB . PubMed: 29634932
  • Carmody M  et al. The ubiquitin-protein ligase E6AP/UBE3A supports early encephalomyocarditis virus replication. Virus Res 252:48-57 (2018). PubMed: 29782878
  • Bo Pan & Julang Li MicroRNA-21 up-regulates metalloprotease by down-regulating TIMP3 during cumulus cell-oocyte complex in vitro maturation. Mol Cell Endocrinol N/A:N/A (2018). WB . PubMed: 29775626
  • Pursell N  et al. Inhibition of Glycogen Synthase II with RNAi Prevents Liver Injury in Mouse Models of Glycogen Storage Diseases. Mol Ther N/A:N/A (2018). WB . PubMed: 29784585
  • Dehghanian F  et al. Network-based expression analyses and experimental validations revealed high co-expression between Yap1 and stem cell markers compared to differentiated cells. Genomics N/A:N/A (2018). Mouse . PubMed: 29775782
  • Ge J  et al. Gold and gold-silver alloy nanoparticles enhance the myogenic differentiation of myoblasts through p38 MAPK signaling pathway and promote in vivo skeletal muscle regeneration. Biomaterials 175:19-29 (2018). WB . PubMed: 29793089
  • Zhang L  et al. Particle-induced SIRT1 downregulation promotes osteoclastogenesis and osteolysis through ER stress regulation. Biomed Pharmacother 104:300-306 (2018). WB ; Mouse . PubMed: 29775898
  • Nowotny K  et al. Oxidants produced by methylglyoxal-modified collagen trigger ER stress and apoptosis in skin fibroblasts. Free Radic Biol Med 120:102-113 (2018). WB ; Human . PubMed: 29550330
  • Askeland G  et al. Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington's disease patients. Sci Rep 8:9817 (2018). WB ; Human . PubMed: 29959348
  • Papakyriakou A  et al. The partial dissociation of MHC class I-bound peptides exposes their N terminus to trimming by endoplasmic reticulum aminopeptidase 1. J Biol Chem 293:7538-7548 (2018). PubMed: 29599287
  • Chen K  et al. Epigallocatechingallate attenuates myocardial injury in a mouse model of heart failure through TGF-ß1/Smad3 signaling pathway. Mol Med Rep 17:7652-7660 (2018). PubMed: 29620209
  • Wei C  et al. Upregulation of UHRF1 promotes the progression of melanoma by inducing cell proliferation. Oncol Rep 39:2553-2562 (2018). PubMed: 29620240
  • Huang D  et al. TPX2 silencing mediated by joint action of microvesicles and ultrasonic radiation inhibits the migration and invasion of SKOV3 cells. Mol Med Rep 17:7627-7635 (2018). PubMed: 29620263
  • Xue D  et al. Long noncoding RNA MALAT1 enhances the docetaxel resistance of prostate cancer cells via miR-145-5p-mediated regulation of AKAP12. J Cell Mol Med 22:3223-3237 (2018). PubMed: 29633510
  • Yang Y  et al. MicroRNA-122 acts as tumor suppressor by targeting TRIM29 and blocking the activity of PI3K/AKT signaling in nasopharyngeal carcinoma in vitro. Mol Med Rep 17:8244-8252 (2018). PubMed: 29693120
  • Kong YH & Xu SP Salidroside prevents skin carcinogenesis induced by DMBA/TPA in a mouse model through suppression of inflammation and promotion of apoptosis. Oncol Rep 39:2513-2526 (2018). PubMed: 29693192
  • Zhang W  et al. Long non-coding RNA-ROR aggravates myocardial ischemia/reperfusion injury. Braz J Med Biol Res 51:e6555 (2018). PubMed: 29694511
  • Chen H  et al. miR-27a protects human mitral valve interstitial cell from TNF-a-induced inflammatory injury via up-regulation of NELL-1. Braz J Med Biol Res 51:e6997 (2018). PubMed: 29694513
  • Tsai SW  et al. Therapeutic Potential of Sclareol in Experimental Models of Rheumatoid Arthritis. Int J Mol Sci 19:N/A (2018). PubMed: 29751535
  • Kovary KM  et al. Expression variation and covariation impair analog and enable binary signaling control. Mol Syst Biol 14:e7997 (2018). PubMed: 29759982
  • Liu Q  et al. UCA1 promotes cell proliferation and invasion and inhibits apoptosis through regulation of the miR129-SOX4 pathway in renal cell carcinoma. Onco Targets Ther 11:2475-2487 (2018). PubMed: 29760557
  • Hoffmann N  et al. DGCR8 Promotes Neural Progenitor Expansion and Represses Neurogenesis in the Mouse Embryonic Neocortex. Front Neurosci 12:281 (2018). PubMed: 29760646
  • Soliman K  et al. Super-resolution imaging reveals the sub-diffraction phenotype of Zellweger Syndrome ghosts and wild-type peroxisomes. Sci Rep 8:7809 (2018). PubMed: 29773809
  • Zhou W  et al. Galectin-3 activates TLR4/NF-?B signaling to promote lung adenocarcinoma cell proliferation through activating lncRNA-NEAT1 expression. BMC Cancer 18:580 (2018). PubMed: 29788922
  • Liu H  et al. Endothelial progenitor cells improve the therapeutic effect of mesenchymal stem cell sheets on irradiated bone defect repair in a rat model. J Transl Med 16:137 (2018). PubMed: 29788957
  • Fu F  et al. HMGA1 exacerbates tumor growth through regulating the cell cycle and accelerates migration/invasion via targeting miR-221/222 in cervical cancer. Cell Death Dis 9:594 (2018). PubMed: 29789601
  • Yang Y  et al. ALG3 Is Activated by Heat Shock Factor 2 and Promotes Breast Cancer Growth. Med Sci Monit 24:3479-3487 (2018). PubMed: 29799832
  • Li CZ  et al. RIP1 regulates TNF-a-mediated lymphangiogenesis and lymphatic metastasis in gallbladder cancer by modulating the NF-?B-VEGF-C pathway. Onco Targets Ther 11:2875-2890 (2018). PubMed: 29844685
  • Yang Y  et al. Euchromatic histone lysine methyltransferase 1 regulates cancer development in human gastric cancer by regulating E-cadherin. Oncol Lett 15:9480-9486 (2018). PubMed: 29844834
  • Martín-Jiménez R  et al. Reduction of the ATPase inhibitory factor 1 (IF1) leads to visual impairment in vertebrates. Cell Death Dis 9:669 (2018). PubMed: 29867190
  • Zhang Y  et al. BYD Ameliorates Oxidative Stress-Induced Myocardial Apoptosis in Heart Failure Post-Acute Myocardial Infarction via the P38 MAPK-CRYAB Signaling Pathway. Front Physiol 9:505 (2018). PubMed: 29867551
  • Xu Y  et al. Long non-coding RNA TUG1 protects renal tubular epithelial cells against injury induced by lipopolysaccharide via regulating microRNA-223. Biomed Pharmacother 104:509-519 (2018). PubMed: 29800915
  • Nandagopal N  et al. Dynamic Ligand Discrimination in the Notch Signaling Pathway. Cell 172:869-880.e19 (2018). PubMed: 29398116
  • Krencz I  et al. In situ analysis of mTORC1/2 and cellular metabolism-related proteins in human Lymphangioleiomyomatosis. Hum Pathol N/A:N/A (2018). PubMed: 29885404
  • Zhang Y  et al. The potential role of thyrotropin-releasing hormone in colonic dysmotility induced by water avoidance stress in rats. Neuropeptides N/A:N/A (2018). WB . PubMed: 29803395
  • Liu K  et al. Functional role of a long non-coding RNA LIFR-AS1/miR-29a/TNFAIP3 axis in colorectal cancer resistance to pohotodynamic therapy. Biochim Biophys Acta N/A:N/A (2018). WB . PubMed: 29807108
  • Qin L  et al. MicroRNA-497 promotes proliferation and inhibits apoptosis of cardiomyocytes through the downregulation of Mfn2 in a mouse model of myocardial ischemia-reperfusion injury. Biomed Pharmacother 105:103-114 (2018). WB . PubMed: 29852387
  • Tanida-Miyake E  et al. Optimization of mNeonGreen for Homo sapiens increases its fluorescent intensity in mammalian cells. PLoS One 13:e0191108 (2018). PubMed: 29342181
  • Liu Q  et al. In vitro cell behaviors of bone mesenchymal stem cells derived from normal and postmenopausal osteoporotic rats. Int J Mol Med 41:669-678 (2018). WB ; Rat . PubMed: 29207050
  • Lu Y  et al. Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVs. Mol Ther Nucleic Acids 10:349-360 (2018). WB . PubMed: 29499946
  • Zhu P  et al. Ripk3 promotes ER stress-induced necroptosis in cardiac IR injury: A mechanism involving calcium overload/XO/ROS/mPTP pathway. Redox Biol 16:157-168 (2018). WB . PubMed: 29502045
  • Yamada Y  et al. Impact of novel oncogenic pathways regulated by antitumor miR-451a in renal cell carcinoma. Cancer Sci 109:1239-1253 (2018). WB . PubMed: 29417701
  • Setz C  et al. Induction of mitophagy in the HEI-OC1 auditory cell line and activation of the Atg12/LC3 pathway in the organ of Corti. Hear Res 361:52-65 (2018). WB . PubMed: 29352609
  • Yang YC  et al. Nuclear translocation of PKM2/AMPK complex sustains cancer stem cell populations under glucose restriction stress. Cancer Lett 421:28-40 (2018). PubMed: 29408265
  • Hao Y  et al. Autophagy mediates the degradation of synaptic vesicles: A potential mechanism of synaptic plasticity injury induced by microwave exposure in rats. Physiol Behav 188:119-127 (2018). WB . PubMed: 29408588
  • Ren L  et al. MiR-155-5p promotes fibroblast cell proliferation and inhibits FOXO signaling pathway in vulvar lichen sclerosis by targeting FOXO3 and CDKN1B. Gene 653:43-50 (2018). WB . PubMed: 29339071
  • Yuan L & Tian J LIN28B promotes the progression of colon cancer by increasing B-cell lymphoma 2 expression. Biomed Pharmacother 103:355-361 (2018). WB ; Human . PubMed: 29669301
  • Dan J  et al. LncRNA-MEG3 inhibits proliferation and metastasis by regulating miRNA-21 in gastric cancer. Biomed Pharmacother 99:931-938 (2018). WB . PubMed: 29710493
  • Li Y  et al. Long non-coding RNA NNT-AS1 affects progression of breast cancer through miR-142-3p/ZEB1 axis. Biomed Pharmacother 103:939-946 (2018). WB . PubMed: 29710510
  • Yu C  et al. Xianyu decoction attenuates the inflammatory response of human lung bronchial epithelial cell. Biomed Pharmacother 102:1092-1098 (2018). WB . PubMed: 29710526
  • Yan X  et al. Cadm2 regulates body weight and energy homeostasis in mice. Mol Metab 8:180-188 (2018). WB ; Mouse . PubMed: 29217450
  • Kramer DA  et al. Fasting and refeeding induces changes in the mouse hepatic lipid droplet proteome. J Proteomics 181:213-224 (2018). WB . PubMed: 29698803
  • Arai T  et al. Regulation of NCAPG by miR-99a-3p (passenger strand) inhibits cancer cell aggressiveness and is involved in CRPC. Cancer Med 7:1988-2002 (2018). WB ; Human . PubMed: 29608247
  • Zhang C  et al. MiR-34a/miR-93 target c-Ski to modulate the proliferaton of rat cardiac fibroblasts and extracellular matrix deposition in vivo and in vitro. Cell Signal 46:145-153 (2018). WB . PubMed: 29551367
  • Zhang L  et al. MicroRNA-30b promotes lipopolysaccharide-induced inflammatory injury and alleviates autophagy through JNK and NF-?B pathways in HK-2 cells. Biomed Pharmacother 101:842-851 (2018). WB . PubMed: 29635893
  • Wang D  et al. MiR-182 promotes prostate cancer progression through activating Wnt/ß-catenin signal pathway. Biomed Pharmacother 99:334-339 (2018). WB . PubMed: 29353209
  • Guo R  et al. Cysteinyl leukotriene receptor 1 regulates glucose-stimulated insulin secretion (GSIS). Cell Signal 46:129-134 (2018). PubMed: 29412178
  • Qu B  et al. SIRT1 suppresses high glucose and palmitate-induced osteoclast differentiation via deacetylating p66Shc. Mol Cell Endocrinol 474:97-104 (2018). WB ; Rat . PubMed: 29486220
  • Chen Y  et al. Porphyromonas gingivalis induced inflammatory responses and promoted apoptosis in lung epithelial cells infected with H1N1 via the Bcl-2/Bax/Caspase-3 signaling pathway. Mol Med Rep 18:97-104 (2018). PubMed: 29750299
  • Pascual F  et al. Modeling the Transition From Decompensated to Pathological Hypertrophy. J Am Heart Assoc 7:N/A (2018). PubMed: 29622588
  • Zhang K  et al. The SHH/Gli axis regulates CD90-mediated liver cancer stem cell function by activating the IL6/JAK2 pathway. J Cell Mol Med 22:3679-3690 (2018). PubMed: 29722127
  • Li L  et al. TRIM22 knockdown suppresses chronic myeloid leukemia via inhibiting PI3K/Akt/mTOR signaling pathway. Cell Biol Int N/A:N/A (2018). PubMed: 29762880
  • McEwen HJL  et al. Feeding and GLP-1 receptor activation stabilize ß-catenin in specific hypothalamic nuclei in male rats. J Neuroendocrinol N/A:e12607 (2018). PubMed: 29752762
  • Luo L  et al. Gasoline exhaust damages spermatogenesis through downregulating a6-integrin and ß1-integrin in the rat model. Andrologia N/A:e13045 (2018). PubMed: 29781095
  • Jin LZ  et al. Silencing SUMO2 promotes protection against degradation and apoptosis of nucleus pulposus cells through p53 signaling pathway in intervertebral disc degeneration. Biosci Rep 38:N/A (2018). PubMed: 29700214
  • Lobato-Márquez D  et al. A requirement for septins and the autophagy receptor p62 in the proliferation of intracellular Shigella. Cytoskeleton (Hoboken) N/A:N/A (2018). PubMed: 29752866
  • Wu Y  et al. SUZ12 is a novel putative oncogene promoting tumorigenesis in head and neck squamous cell carcinoma. J Cell Mol Med 22:3582-3594 (2018). PubMed: 29667751
  • Yamada Y  et al. Anti-tumor roles of both strands of the miR-455 duplex: their targets SKA1 and SKA3 are involved in the pathogenesis of renal cell carcinoma. Oncotarget 9:26638-26658 (2018). PubMed: 29928475
  • Xu H  et al. Physiological and biochemical characteristics of skeletal muscles in sedentary and active rats. J Muscle Res Cell Motil N/A:N/A (2018). PubMed: 29948664
  • Wu DM  et al. MicroRNA-17 inhibition overcomes chemoresistance and suppresses epithelial-mesenchymal transition through a DEDD-dependent mechanism in gastric cancer. Int J Biochem Cell Biol 102:59-70 (2018). PubMed: 29953965
  • Xu X  et al. Knockdown of long noncoding RNA XIST alleviates oxidative low-density lipoprotein-mediated endothelial cells injury through modulation of miR-320/NOD2 axis. Biochem Biophys Res Commun 503:586-592 (2018). PubMed: 29902461
  • Khodadadi D  et al. Treadmill Exercise Ameliorates Spatial Learning and Memory Deficits Through Improving the Clearance of Peripheral and Central Amyloid-Beta Levels. Neurochem Res 43:1561-1574 (2018). PubMed: 29948724
  • Li G  et al. SIRT1 inhibits rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and inflammatory response via suppressing NF-?B pathway. Biosci Rep 38:N/A (2018). PubMed: 29784872
  • Chen Y  et al. Berberine suppresses apoptosis and extracellular matrix (ECM) degradation in nucleus pulposus cells and ameliorates disc degeneration in a rodent model. Int J Biol Sci 14:682-692 (2018). PubMed: 29904282
  • Oldoni F  et al. Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans. Arterioscler Thromb Vasc Biol 38:1440-1453 (2018). PubMed: 29853565
  • Eastwood MP  et al. MicroRNA 200b is upregulated in the lungs of fetal rabbits with surgically induced diaphragmatic hernia. Prenat Diagn 38:645-653 (2018). PubMed: 29932217
  • Hu T  et al. Spermine oxidase is upregulated and promotes tumor growth in hepatocellular carcinoma. Hepatol Res N/A:N/A (2018). PubMed: 29923661
  • Sun T  et al. An Immunosuppressive Tick Salivary Gland Protein DsCystatin Interferes With Toll-Like Receptor Signaling by Downregulating TRAF6. Front Immunol 9:1245 (2018). PubMed: 29922290
  • Gang X  et al. Treatment effect of CDKN1A on rheumatoid arthritis by mediating proliferation and invasion of fibroblast-like synoviocytes cells. Clin Exp Immunol N/A:N/A (2018). PubMed: 29920650
  • Mali GR  et al. ZMYND10 functions in a chaperone relay during axonemal dynein assembly. Elife 7:N/A (2018). PubMed: 29916806
  • Little D  et al. A single cell high content assay detects mitochondrial dysfunction in iPSC-derived neurons with mutations in SNCA. Sci Rep 8:9033 (2018). PubMed: 29899557
  • Qu X  et al. Downregulation of TBC1 Domain Family Member 24 (BC1D24) Inhibits Breast Carcinoma Growth via IGF1R/PI3K/AKT Pathway. Med Sci Monit 24:3987-3996 (2018). PubMed: 29893377
  • Sonzogni O  et al. Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo. PLoS Biol 16:e2004049 (2018). PubMed: 29924804
  • Jia S  et al. Overexpression of indoleamine 2, 3-dioxygenase contributes to the repair of human airway epithelial cells inhibited by dexamethasone via affecting the MAPK/ERK signaling pathway. Exp Ther Med 16:282-290 (2018). PubMed: 29896251
  • Bösl K  et al. Coactivation of TLR2 and TLR8 in Primary Human Monocytes Triggers a Distinct Inflammatory Signaling Response. Front Physiol 9:618 (2018). PubMed: 29896111
  • Fa Z  et al. MicroRNA-150 suppresses the growth and malignant behavior of papillary thyroid carcinoma cells via downregulation of MUC4. Exp Ther Med 16:45-52 (2018). PubMed: 29896226
  • Wall MJ  et al. The Temporal Dynamics of Arc Expression Regulate Cognitive Flexibility. Neuron 98:1124-1132.e7 (2018). PubMed: 29861284
  • Chen W  et al. Overexpression of GRIM-19 accelerates radiation-induced osteosarcoma cells apoptosis by p53 stabilization. Life Sci 208:232-238 (2018). PubMed: 30005830
  • Stein T  et al. Interferon regulatory factor 5 and nuclear factor kappa-B exhibit cooperating but also divergent roles in the regulation of pro-inflammatory cytokines important for the development of TH1 and TH17 responses. FEBS J N/A:N/A (2018). PubMed: 29971953
  • Ritter ML  et al. Frontotemporal Dementia-Associated N279K Tau Mutation Localizes at the Nuclear Compartment. Front Cell Neurosci 12:202 (2018). PubMed: 30050413
  • Nielsen KO  et al. Hepatitis B virus suppresses the secretion of insulin-like growth factor binding protein 1 to facilitate anti-apoptotic IGF-1 effects in HepG2 cells. Exp Cell Res 370:399-408 (2018). PubMed: 29981339
  • Sheng J  et al. M2 macrophage-mediated interleukin-4 signalling induces myofibroblast phenotype during the progression of benign prostatic hyperplasia. Cell Death Dis 9:755 (2018). PubMed: 29988032
  • Yang WH  et al. Heterogeneous nuclear ribonucleoprotein M promotes the progression of breast cancer by regulating the axin/ß-catenin signaling pathway. Biomed Pharmacother 105:848-855 (2018). PubMed: 30021377
  • Dong Y  et al. Significance of Methylation of FBP1 Gene in Non-Small Cell Lung Cancer. Biomed Res Int 2018:3726091 (2018). PubMed: 29984231
  • Trepiana J  et al. Unraveling the in vitro antitumor activity of Vismia baccifera against HepG2: role of hydrogen peroxide. Heliyon 4:e00675 (2018). PubMed: 30003166
  • Wang L  et al. CCR7 regulates ANO6 to promote migration of pancreatic ductal adenocarcinoma cells via the ERK signaling pathway. Oncol Lett 16:2599-2605 (2018). PubMed: 30013654
  • Chen W  et al. Downregulation of lncRNA OGFRP1 inhibits hepatocellular carcinoma progression by AKT/mTOR and Wnt/ß-catenin signaling pathways. Cancer Manag Res 10:1817-1826 (2018). PubMed: 29997441
  • Gao X  et al. The Combination of Human Urinary Kallidinogenase and Mild Hypothermia Protects Adult Rats Against Hypoxic-Ischemic Encephalopathy-Induced Injury by Promoting Angiogenesis and Regeneration. Front Aging Neurosci 10:196 (2018). PubMed: 30050428
  • Hodgkinson K  et al. GREB1 is an estrogen receptor-regulated tumour promoter that is frequently expressed in ovarian cancer. Oncogene N/A:N/A (2018). PubMed: 29973689
  • Zhao Y  et al. Prognostic value of association of OCT4 with LEF1 expression in esophageal squamous cell carcinoma and their impact on epithelial-mesenchymal transition, invasion, and migration. Cancer Med 7:3977-3987 (2018). PubMed: 29974668
  • Hock EM  et al. Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function. Cell Rep 24:987-1000.e7 (2018). PubMed: 30044993
  • Sun M  et al. MicroRNA-378 regulates epithelial-mesenchymal transition and metastasis of melanoma by inhibiting FOXN3 expression through the Wnt/ß-catenin pathway. Cell Biol Int N/A:N/A (2018). PubMed: 29972255
  • Li D  et al. Armadillo repeat containing 12 promotes neuroblastoma progression through interaction with retinoblastoma binding protein 4. Nat Commun 9:2829 (2018). PubMed: 30026490
  • Liao K  et al. SB431542 inhibited cigarette smoke extract induced invasiveness of A549 cells via the TGF-ß1/Smad2/MMP3 pathway. Oncol Lett 15:9681-9686 (2018). PubMed: 29963124
  • Gilmour J  et al. The Co-operation of RUNX1 with LDB1, CDK9 and BRD4 Drives Transcription Factor Complex Relocation During Haematopoietic Specification. Sci Rep 8:10410 (2018). PubMed: 29991720
  • Bukuroshi P  et al. Strategies and limitations associated with in vitro characterization of vitamin D receptor activators. Biochem Pharmacol 155:547-561 (2018). PubMed: 30028992
  • Zhang Y  et al. Novel ADAM-17 inhibitor ZLDI-8 enhances the in vitro and in vivo chemotherapeutic effects of Sorafenib on hepatocellular carcinoma cells. Cell Death Dis 9:743 (2018). PubMed: 29970890
  • Ma CT  et al. Fusobacterium nucleatum promotes the progression of colorectal cancer by interacting with E-cadherin. Oncol Lett 16:2606-2612 (2018). PubMed: 30013655
  • Qadir F  et al. Transcriptome reprogramming by cancer exosomes: identification of novel molecular targets in matrix and immune modulation. Mol Cancer 17:97 (2018). PubMed: 30008265
  • Zhao S  et al. Maternal exposure to di-n-butyl phthalate (DBP) promotes epithelial-mesenchymal transition via regulation of autophagy in uroepithelial cell. Toxicology 406-407:114-122 (2018). PubMed: 30053495
  • Pavel M  et al. Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis. Nat Commun 9:2961 (2018). PubMed: 30054475
  • Richardson CD  et al. CRISPR-Cas9 genome editing in human cells occurs via the Fanconi anemia pathway. Nat Genet 50:1132-1139 (2018). PubMed: 30054595
  • Sauvat A  et al. Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids. EBioMedicine 30:261-272 (2018). WB . PubMed: 29606629
  • Griveau A  et al. A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment. Cancer Cell 33:874-889.e7 (2018). PubMed: 29681511
  • Su M  et al. miR-885-5p upregulation promotes colorectal cancer cell proliferation and migration by targeting suppressor of cytokine signaling. Oncol Lett 16:65-72 (2018). WB ; Human . PubMed: 29928388
  • Beermann J  et al. A large shRNA library approach identifies lncRNA Ntep as an essential regulator of cell proliferation. Cell Death Differ 25:307-318 (2018). PubMed: 29099486
  • Zhang Y  et al. Matrine suppresses cardiac fibrosis by inhibiting the TGF-ß/Smad pathway in experimental diabetic cardiomyopathy. Mol Med Rep 17:1775-1781 (2018). PubMed: 29138820
  • Dang T  et al. Autism-associated Dyrk1a truncation mutants impair neuronal dendritic and spine growth and interfere with postnatal cortical development. Mol Psychiatry 23:747-758 (2018). PubMed: 28167836
  • Xu X  et al. Network analysis of DEGs and verification experiments reveal the notable roles of PTTG1 and MMP9 in lung cancer. Oncol Lett 15:257-263 (2018). PubMed: 29387220
  • Sun LQ  et al. Effects of MicroRNA-592-5p on Hippocampal Neuron Injury Following Hypoxic-Ischemic Brain Damage in Neonatal Mice - Involvement of PGD2/DP and PTGDR. Cell Physiol Biochem 45:458-473 (2018). PubMed: 29402808
  • Liu F  et al. SRSF10-mediated IL1RAP alternative splicing regulates cervical cancer oncogenesis via mIL1RAP-NF-?B-CD47 axis. Oncogene 37:2394-2409 (2018). PubMed: 29429992
  • Pei J  et al. TCF4/ß-catenin complex is directly upstream of FGF21 in mouse stomach cancer cells. Exp Ther Med 15:1041-1047 (2018). PubMed: 29434695
  • Sun W  et al. miR-4262 regulates chondrocyte viability, apoptosis, autophagy by targeting SIRT1 and activating PI3K/AKT/mTOR signaling pathway in rats with osteoarthritis. Exp Ther Med 15:1119-1128 (2018). PubMed: 29434702
  • Lu G  et al. Expression and role of microRNA-1271 in the pathogenesis of osteosarcoma. Exp Ther Med 15:1934-1940 (2018). PubMed: 29434787
  • Han L  et al. Long non-coding RNA SOX2OT promotes cell proliferation and motility in human ovarian cancer. Exp Ther Med 15:2182-2188 (2018). PubMed: 29434823
  • Zeng L  et al. Long non-coding RNA MALAT-1 contributes to maintenance of stem cell-like phenotypes in breast cancer cells. Oncol Lett 15:2117-2122 (2018). PubMed: 29434914
  • Liu F  et al. A novel approach to glioma therapy using an oncolytic adenovirus with two specific promoters. Oncol Lett 15:3362-3368 (2018). PubMed: 29435080
  • Miao XL  et al. Asiatic acid attenuates high-fat diet-induced impaired spermatogenesis. Exp Ther Med 15:2397-2403 (2018). PubMed: 29467846
  • Lang B & Zhao S miR-486 functions as a tumor suppressor in esophageal cancer by targeting CDK4/BCAS2. Oncol Rep 39:71-80 (2018). PubMed: 29115564
  • Wang Y & Kong D LncRNA GAS5 Represses Osteosarcoma Cells Growth and Metastasis via Sponging MiR-203a. Cell Physiol Biochem 45:844-855 (2018). PubMed: 29414815
  • Avanzato D  et al. High USP6NL Levels in Breast Cancer Sustain Chronic AKT Phosphorylation and GLUT1 Stability Fueling Aerobic Glycolysis. Cancer Res 78:3432-3444 (2018). PubMed: 29691252
  • Li Z  et al. Targeting the miR-665-3p-ATG4B-autophagy axis relieves inflammation and apoptosis in intestinal ischemia/reperfusion. Cell Death Dis 9:483 (2018). PubMed: 29706629
  • Wang Y  et al. Local honokiol application inhibits intimal thickening in rabbits following carotid artery balloon injury. Mol Med Rep 17:1683-1689 (2018). PubMed: 29257208
  • Luan Y  et al. Codonopis bulleynana Forest ex Diels inhibits autophagy and induces apoptosis of colon cancer cells by activating the NF-?B signaling pathway. Int J Mol Med 41:1305-1314 (2018). PubMed: 29286074
  • Dai F  et al. Downregulation of MiR-199b-5p Inducing Differentiation of Bone-Marrow Mesenchymal Stem Cells (BMSCs) Toward Cardiomyocyte-Like Cells via HSF1/HSP70 Pathway. Med Sci Monit 24:2700-2710 (2018). PubMed: 29715263
  • Lu J  et al. MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function. Oncogene 37:3864-3878 (2018). PubMed: 29662197
  • Wang S  et al. Effect of aromatase inhibitor letrozole on the proliferation of spermatogonia by regulating the MAPK pathway. Exp Ther Med 15:5269-5274 (2018). PubMed: 29805545
  • Li XQ  et al. Liquiritin suppresses UVB-induced skin injury through prevention of inflammation, oxidative stress and apoptosis through the TLR4/MyD88/NF-?B and MAPK/caspase signaling pathways. Int J Mol Med 42:1445-1459 (2018). PubMed: 29901082
  • Shan L  et al. Expression of vitamin D receptor in bronchial asthma and its bioinformatics prediction. Mol Med Rep 18:2052-2060 (2018). PubMed: 29901144
  • Ke K  et al. Downregulation of long non-coding RNA GAS5 promotes cell proliferation, migration and invasion in esophageal squamous cell carcinoma. Oncol Lett 16:1801-1808 (2018). PubMed: 30008868
  • Zhang H  et al. Loss of profilin 2 contributes to enhanced epithelial-mesenchymal transition and metastasis of colorectal cancer. Int J Oncol 53:1118-1128 (2018). PubMed: 30015842
  • Cui M  et al. Upregulation of lncRNA-ATB by Transforming Growth Factor ß1 (TGF-ß1) Promotes Migration and Invasion of Papillary Thyroid Carcinoma Cells. Med Sci Monit 24:5152-5158 (2018). PubMed: 30042377
  • Tsai MS  et al. Galectin-1 Restricts Vascular Smooth Muscle Cell Motility Via Modulating Adhesion Force and Focal Adhesion Dynamics. Sci Rep 8:11497 (2018). PubMed: 30065303
  • Ma J  et al. Altered expression of TIAM1 in endotoxin-challenged airway epithelial cells and rodent septic models. J Thorac Dis 10:3187-3195 (2018). PubMed: 30069314
  • Hollingsworth TJ  et al. Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4). Invest Ophthalmol Vis Sci 59:3808-3815 (2018). PubMed: 30073354
  • Zhang X & Xiao C Ultrasonic diagnosis combined with targeted ultrasound contrast agent improves diagnostic sensitivity of ultrasonic for non-small cell lung cancer patients. Exp Ther Med 16:908-916 (2018). PubMed: 30112043
  • Tian X  et al. MicroRNA-199a-5p aggravates primary hypertension by damaging vascular endothelial cells through inhibition of autophagy and promotion of apoptosis. Exp Ther Med 16:595-602 (2018). PubMed: 30116316
  • Li Y  et al. Dual targeting of survivin and X-linked inhibitor of apoptosis protein suppresses the growth and promotes the apoptosis of gastric cancer HGC-27 cells. Oncol Lett 16:3489-3498 (2018). PubMed: 30127953
  • Rademaker G  et al. Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness. Oncogene 37:4398-4412 (2018). PubMed: 29720728
  • Kim SH  et al. Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis. Dis Model Mech 11:N/A (2018). PubMed: 29784888
  • Pfanzelter J  et al. Septins suppress the release of vaccinia virus from infected cells. J Cell Biol 217:2911-2929 (2018). PubMed: 29921601
  • Chen SY  et al. MicroRNA-340 Inhibits Epithelial-Mesenchymal Transition by Impairing ROCK-1-Dependent Wnt/ß-Catenin Signaling Pathway in Epithelial Cells from Human Benign Prostatic Hyperplasia. Chin Med J (Engl) 131:2008-2012 (2018). PubMed: 30082536
  • Liu C  et al. APP upregulation contributes to retinal ganglion cell degeneration via JNK3. Cell Death Differ 25:661-676 (2018). PubMed: 29238071
  • Dyar KA  et al. Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock. PLoS Biol 16:e2005886 (2018). PubMed: 30096135
  • Singh M  et al. Gai3 signaling is associated with sexual dimorphic expression of the clock-controlled output gene Dbp in murine liver. Oncotarget 9:30213-30224 (2018). PubMed: 30100984
  • Jin Q  et al. High Spy1 expression predicts poor prognosis in colorectal cancer. Cancer Manag Res 10:2757-2765 (2018). PubMed: 30147372
  • Qu M  et al. MicroRNA-138 inhibits SOX12 expression and the proliferation, invasion and migration of ovarian cancer cells. Exp Ther Med 16:1629-1638 (2018). PubMed: 30186381
  • Wang Y  et al. Wnt3a-regulated TCF4/ß-catenin complex directly activates the key Hedgehog signalling genes Smo and Gli1. Exp Ther Med 16:2101-2107 (2018). PubMed: 30186446
  • Huang X & Lyu J Tumor suppressor function of miR-483-3p on breast cancer via targeting of the cyclin E1 gene. Exp Ther Med 16:2615-2620 (2018). PubMed: 30186493
  • Zhang S  et al. Up-regulation of microRNA-203 in influenza A virus infection inhibits viral replication by targeting DR1. Sci Rep 8:6797 (2018). WB . PubMed: 29717211
  • Klett EL  et al. Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acids. J Lipid Res 58:884-894 (2017). PubMed: 28209804
  • Phillips AF  et al. Single-Molecule Analysis of mtDNA Replication Uncovers the Basis of the Common Deletion. Mol Cell 65:527-538.e6 (2017). PubMed: 28111015
  • Semple BD  et al. Interleukin-1 Receptor in Seizure Susceptibility after Traumatic Injury to the Pediatric Brain. J Neurosci 37:7864-7877 (2017). PubMed: 28724747
  • Cortada M  et al. Brimonidine Protects Auditory Hair Cells from in vitro-Induced Toxicity of Gentamicin. Audiol Neurootol 22:125-134 (2017). PubMed: 28889125
  • Moghadam FH  et al. Effects of Oleo Gum Resin of Ferula assa-foetida L. on Senescence in Human Dermal Fibroblasts: - Asafoetida reverses senescence in fibroblasts. J Pharmacopuncture 20:213-219 (2017). PubMed: 30087798
  • Pan L  et al. Shear stress induces human aortic endothelial cell apoptosis via interleukin-1 receptor-associated kinase 2-induced endoplasmic reticulum stress. Mol Med Rep 16:7205-7212 (2017). PubMed: 28944871
  • Zhang XJ  et al. 17ß-estradiol protects against doxorubicin-induced cardiotoxicity in male Sprague-Dawley rats by regulating NADPH oxidase and apoptosis genes. Mol Med Rep 15:2695-2702 (2017). PubMed: 28447737
  • Esteban-Martínez L  et al. Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J 36:1688-1706 (2017). PubMed: 28465321
  • Hu HJ  et al. Protective effects of hydrogen sulfide against angiotensin II-induced endoplasmic reticulum stress in HUVECs. Mol Med Rep 15:2213-2222 (2017). PubMed: 28259956
  • Sato Y  et al. Regulatory signatures of liver regeneration distilled by integrative analysis of mRNA, histone methylation, and proteomics. J Biol Chem 292:8019-8037 (2017). PubMed: 28302717
  • Chen X  et al. Alcohol Induces Cellular Senescence and Impairs Osteogenic Potential in Bone Marrow-Derived Mesenchymal Stem Cells. Alcohol Alcohol 52:289-297 (2017). PubMed: 28339869
  • Li S  et al. Exposure to fermentation supernatant of Staphylococcus aureus accelerated dedifferentiation of chondrocytes and production of antimicrobial peptides. J Orthop Res N/A:N/A (2017). PubMed: 28513981
  • Skinner CM  et al. An Epstein-Barr Virus MicroRNA Blocks Interleukin-1 (IL-1) Signaling by Targeting IL-1 Receptor 1. J Virol 91:N/A (2017). PubMed: 28794034
  • Chen L  et al. Juglanin inhibits lung cancer by regulation of apoptosis, ROS and autophagy induction. Oncotarget 8:93878-93898 (2017). PubMed: 29212196
  • Garg N  et al. CD133+ brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence. Oncogene 36:606-617 (2017). PubMed: 27775079
  • Dzinic SH  et al. An Essential Role of Maspin in Embryogenesis and Tumor Suppression. Cancer Res 77:886-896 (2017). PubMed: 27923833
  • Yu C  et al. Advanced oxidation protein products induce apoptosis, and upregulate sclerostin and RANKL expression, in osteocytic MLO-Y4 cells via JNK/p38 MAPK activation. Mol Med Rep 15:543-550 (2017). PubMed: 28000869
  • Cochrane A  et al. Quaking Is a Key Regulator of Endothelial Cell Differentiation, Neovascularization, and Angiogenesis. Stem Cells 35:952-966 (2017). PubMed: 28207177
  • Singh DK  et al. SRC family kinases in hamster spermatozoa: evidence for the presence of LCK. Reproduction 153:655-669 (2017). PubMed: 28250239
  • Tang J  et al. Bidirectional transcription of Linc00441 and RB1 via H3K27 modification-dependent way promotes hepatocellular carcinoma. Cell Death Dis 8:e2675 (2017). PubMed: 28300839
  • Zou L  et al. Molecular cloning, characterization and expression analysis of Frizzled 6 in the small intestine of pigs (Sus scrofa). PLoS One 12:e0179421 (2017). PubMed: 28614361
  • Yao CJ  et al. Induction of Forkhead Class box O3a and apoptosis by a standardized ginsenoside formulation, KG-135, is potentiated by autophagy blockade in A549 human lung cancer cells. J Ginseng Res 41:247-256 (2017). PubMed: 28701864
  • Tang F  et al. CT45A1 siRNA silencing suppresses the proliferation, metastasis and invasion of lung cancer cells by downregulating the ERK/CREB signaling pathway. Mol Med Rep 16:6708-6714 (2017). PubMed: 28901509
  • Piston D  et al. DJ-1 is a redox sensitive adapter protein for high molecular weight complexes involved in regulation of catecholamine homeostasis. Hum Mol Genet 26:4028-4041 (2017). PubMed: 29016861
  • Furukawa KT  et al. The Epithelial Circumferential Actin Belt Regulates YAP/TAZ through Nucleocytoplasmic Shuttling of Merlin. Cell Rep 20:1435-1447 (2017). PubMed: 28793266
  • Cui S  et al. MicroRNA-137 has a suppressive role in liver cancer via targeting EZH2. Mol Med Rep 16:9494-9502 (2017). PubMed: 29152663
  • Yang S  et al. Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides. Front Aging Neurosci 9:435 (2017). PubMed: 29358916
  • Kim Y & Hood DA Regulation of the autophagy system during chronic contractile activity-induced muscle adaptations. Physiol Rep 5:N/A (2017). PubMed: 28720712
  • Lawrence KM  et al. Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1. Sci Rep 7:5147 (2017). WB . PubMed: 28698554
  • Po A  et al. Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma. Oncogene 36:4641-4652 (2017). PubMed: 28368412
  • Du Z  et al. Differential Alteration in Expression of Striatal GABAAR Subunits in Mouse Models of Huntington's Disease. Front Mol Neurosci 10:198 (2017). WB ; Mouse . PubMed: 28676743
  • Song DD  et al. Sphingosine kinase 2 activates autophagy and protects neurons against ischemic injury through interaction with Bcl-2 via its putative BH3 domain. Cell Death Dis 8:e2912 (2017). PubMed: 28682313
  • Martín-Maestro P  et al. Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer's Disease-Associated Presenilin 1 Mutation. Front Mol Neurosci 10:291 (2017). PubMed: 28959184
  • Sargiacomo C  et al. Upregulation of sodium taurocholate cotransporter polypeptide during hepatogenic differentiation of umbilical cord matrix mesenchymal stem cells facilitates hepatitis B entry. Stem Cell Res Ther 8:204 (2017). WB . PubMed: 28962642
  • Chen J  et al. CD146 coordinates brain endothelial cell-pericyte communication for blood-brain barrier development. Proc Natl Acad Sci U S A 114:E7622-E7631 (2017). PubMed: 28827364
  • Moiseeva T  et al. ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1. Nat Commun 8:1392 (2017). PubMed: 29123096
  • Tan Y  et al. Soft matrices downregulate FAK activity to promote growth of tumor-repopulating cells. Biochem Biophys Res Commun 483:456-462 (2017). WB ; Human . PubMed: 28007596
  • Mor DE  et al. Dopamine induces soluble a-synuclein oligomers and nigrostriatal degeneration. Nat Neurosci 20:1560-1568 (2017). WB ; Mouse . PubMed: 28920936
  • Martiskainen H  et al. DHCR24 exerts neuroprotection upon inflammation-induced neuronal death. J Neuroinflammation 14:215 (2017). WB . PubMed: 29115990
  • Lin J  et al. Kindlin-2 promotes hepatocellular carcinoma invasion and metastasis by increasing Wnt/ß-catenin signaling. J Exp Clin Cancer Res 36:134 (2017). WB . PubMed: 28969700
  • Feuerstein M  et al. Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line. Cell Tissue Res 370:211-225 (2017). PubMed: 28799057
  • Sanz RL  et al. Ectodomain shedding of Limbic System-Associated Membrane Protein (LSAMP) by ADAM Metallopeptidases promotes neurite outgrowth in DRG neurons. Sci Rep 7:7961 (2017). IF ; Rat . PubMed: 28801670
  • Meister M  et al. Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo. Oncogenesis 6:e344 (2017). PubMed: 28581508
  • Bargagna-Mohan P  et al. Sustained activation of ERK1/2 MAPK in Schwann cells causes corneal neurofibroma. J Neurosci Res 95:1712-1729 (2017). WB . PubMed: 28489286
  • Lopez-Guerrero AM  et al. Store-operated calcium entry is dispensable for the activation of ERK1/2 pathway in prostate cancer cells. Cell Signal 40:44-52 (2017). PubMed: 28866365
  • Moretti AIS  et al. Conserved Gene Microsynteny Unveils Functional Interaction Between Protein Disulfide Isomerase and Rho Guanine-Dissociation Inhibitor Families. Sci Rep 7:17262 (2017). WB ; Mouse . PubMed: 29222525
  • Schlütermann D  et al. Targeting urothelial carcinoma cells by combining cisplatin with a specific inhibitor of the autophagy-inducing class III PtdIns3K complex. Urol Oncol N/A:N/A (2017). Human . PubMed: 29276062
  • Gong S  et al. Roflumilast restores cAMP/PKA/CREB signaling axis for FtMt-mediated tumor inhibition of ovarian cancer. Oncotarget 8:112341-112353 (2017). PubMed: 29348829
  • Rathjen T  et al. Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1. Nat Neurosci 20:1096-1103 (2017). WB . PubMed: 28628102
  • Chen L  et al. MiR-29b-3p promotes chondrocyte apoptosis and facilitates the occurrence and development of osteoarthritis by targeting PGRN. J Cell Mol Med 21:3347-3359 (2017). WB . PubMed: 28609022
  • Paakinaho V  et al. Single-molecule analysis of steroid receptor and cofactor action in living cells. Nat Commun 8:15896 (2017). WB . PubMed: 28635963
  • Evans AJ  et al. Assembly, Secretory Pathway Trafficking, and Surface Delivery of Kainate Receptors Is Regulated by Neuronal Activity. Cell Rep 19:2613-2626 (2017). WB . PubMed: 28636947
  • Koshizuka K  et al. Regulation of ITGA3 by the anti-tumor miR-199 family inhibits cancer cell migration and invasion in head and neck cancer. Cancer Sci 108:1681-1692 (2017). WB ; Human . PubMed: 28612520
  • Khakipoor S  et al. TGF-ß signaling directly regulates transcription and functional expression of the electrogenic sodium bicarbonate cotransporter 1, NBCe1 (SLC4A4), via Smad4 in mouse astrocytes. Glia 65:1361-1375 (2017). PubMed: 28568893
  • Liu Y  et al. Clinicopathological and prognostic significance of PKM2 protein expression in cirrhotic hepatocellular carcinoma and non-cirrhotic hepatocellular carcinoma. Sci Rep 7:15294 (2017). WB ; Human . PubMed: 29127353
  • Chen D  et al. ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner. Oncogene 36:5593-5608 (2017). PubMed: 28553953
  • Ghadge SK  et al. Prolyl-hydroxylase inhibition induces SDF-1 associated with increased CXCR4+/CD11b+ subpopulations and cardiac repair. J Mol Med (Berl) 95:825-837 (2017). WB ; Mouse . PubMed: 28550361
  • Zhao D  et al. MicroRNA-128 promotes apoptosis in lung cancer by directly targeting NIMA-related kinase 2. Thorac Cancer 8:304-311 (2017). WB ; Human . PubMed: 28514100
  • Wang MS  et al. Iron oxide magnetic nanoparticles combined with actein suppress non-small-cell lung cancer growth in a p53-dependent manner. Int J Nanomedicine 12:7627-7651 (2017). WB ; Human . PubMed: 29089760
  • Iruarrizaga-Lejarreta M  et al. Role of Aramchol in steatohepatitis and fibrosis in mice. Hepatol Commun 1:911-927 (2017). WB . PubMed: 29159325
  • Wang P  et al. Long Noncoding RNA H19 Inhibits Cell Viability, Migration, and Invasion Via Downregulation of IRS-1 in Thyroid Cancer Cells. Technol Cancer Res Treat 16:1102-1112 (2017). PubMed: 29332545
  • Kim HR  et al. MicroRNA-1908-5p contributes to the oncogenic function of the splicing factor SRSF3. Oncotarget 8:8342-8355 (2017). PubMed: 28039456
  • Po A  et al. ß-Arrestin1/miR-326 Transcription Unit Is Epigenetically Regulated in Neural Stem Cells Where It Controls Stemness and Growth Arrest. Stem Cells Int 2017:5274171 (2017). PubMed: 28298929
  • König HG  et al. NF-?B regulates neuronal ankyrin-G via a negative feedback loop. Sci Rep 7:42006 (2017). PubMed: 28181483
  • Lee H  et al. MicroRNA-296-5p Promotes Invasiveness through Downregulation of Nerve Growth Factor Receptor and Caspase-8. Mol Cells 40:254-261 (2017). PubMed: 27927008
  • Larabee JL  et al. Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB. MBio 8:N/A (2017). PubMed: 28512094
  • Kugita M  et al. Beneficial effect of combined treatment with octreotide and pasireotide in PCK rats, an orthologous model of human autosomal recessive polycystic kidney disease. PLoS One 12:e0177934 (2017). PubMed: 28542433
  • Han J & Wang W Effects of tanshinol on markers of bone turnover in ovariectomized rats and osteoblast cultures. PLoS One 12:e0181175 (2017). PubMed: 28746340
  • Rezaee F  et al. cAMP-dependent activation of protein kinase A attenuates respiratory syncytial virus-induced human airway epithelial barrier disruption. PLoS One 12:e0181876 (2017). PubMed: 28759570
  • Takaki T  et al. Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability. Nat Commun 8:16013 (2017). PubMed: 28737169
  • Marshall AD  et al. ASCT2 regulates glutamine uptake and cell growth in endometrial carcinoma. Oncogenesis 6:e367 (2017). PubMed: 28759021
  • Wen Z  et al. Identification of autism-related MECP2 mutations by whole-exome sequencing and functional validation. Mol Autism 8:43 (2017). PubMed: 28785396
  • Byon IS  et al. Effect of angiotensin II type 1 receptor blocker and angiotensin converting enzyme inhibitor on the intraocular growth factors and their receptors in streptozotocin-induced diabetic rats. Int J Ophthalmol 10:896-901 (2017). PubMed: 28730079
  • Liu X  et al. Laminarin protects against hydrogen peroxide-induced oxidative damage in MRC-5 cells possibly via regulating NRF2. PeerJ 5:e3642 (2017). PubMed: 28785522
  • Shen L  et al. C-X-C motif chemokine ligand 8 promotes endothelial cell homing via the Akt-signal transducer and activator of transcription pathway to accelerate healing of ischemic and hypoxic skin ulcers. Exp Ther Med 13:3021-3031 (2017). PubMed: 28587375
  • Sim SH  et al. CKAP2 (cytoskeleton-associated protein2) is a new prognostic marker in HER2-negative luminal type breast cancer. PLoS One 12:e0182107 (2017). PubMed: 28771517
  • Takata T  et al. Generation of glyceraldehyde-derived advanced glycation end-products in pancreatic cancer cells and the potential of tumor promotion. World J Gastroenterol 23:4910-4919 (2017). PubMed: 28785145
  • Hong X  et al. Transdifferentiated Human Vascular Smooth Muscle Cells are a New Potential Cell Source for Endothelial Regeneration. Sci Rep 7:5590 (2017). PubMed: 28717251
  • Wang Y  et al. MicroRNA-152 regulates immune response via targeting B7-H1 in gastric carcinoma. Oncotarget 8:28125-28134 (2017). PubMed: 28427226
  • Jiang L  et al. Similarity in the functions of HIF-1a and HIF-2a proteins in cervical cancer cells. Oncol Lett 14:5643-5651 (2017). PubMed: 29098039
  • Guo C  et al. The expression and clinical significance of ZBTB7 in transitional cell carcinoma of the bladder. Oncol Lett 14:4857-4862 (2017). PubMed: 29085492
  • Shi Q  et al. Differentiation of human umbilical cord Wharton's jelly-derived mesenchymal stem cells into endometrial cells. Stem Cell Res Ther 8:246 (2017). PubMed: 29096715
  • Wang S  et al. Expression and role of microRNA 18b and hypoxia inducible factor-1a in placental tissues of preeclampsia patients. Exp Ther Med 14:4554-4560 (2017). PubMed: 29104664
  • Adamkova K  et al. SIRT1-dependent modulation of methylation and acetylation of histone H3 on lysine 9 (H3K9) in the zygotic pronuclei improves porcine embryo development. J Anim Sci Biotechnol 8:83 (2017). PubMed: 29118980
  • Jin P  et al. Essential role of microRNA-650 in the regulation of B-cell CLL/lymphoma 11B gene expression following transplantation: A novel mechanism behind the acute rejection of renal allografts. Int J Mol Med 40:1840-1850 (2017). PubMed: 29039465
  • Chen Y  et al. Nuclear factor-?B signaling negatively regulates high glucose-induced vascular endothelial cell damage downstream of the extracellular signal-regulated kinase/c-Jun N-terminal kinase pathway. Exp Ther Med 14:3851-3855 (2017). PubMed: 29042991
  • Wei F  et al. Liquiritin induces apoptosis and autophagy in cisplatin (DDP)-resistant gastric cancer cells in vitro and xenograft nude mice in vivo. Int J Oncol 51:1383-1394 (2017). PubMed: 29048624
  • Ehrnström B  et al. Toll-Like Receptor 8 Is a Major Sensor of Group BStreptococcusBut NotEscherichia coliin Human Primary Monocytes and Macrophages. Front Immunol 8:1243 (2017). PubMed: 29042860
  • Xue H  et al. Tiaogeng Yijing decoction improves the pregnancy outcomes of patients with poor ovarian response undergoingin vitrofertilization-embryo transfer. Exp Ther Med 14:3935-3941 (2017). PubMed: 29043003
  • Sansregret L  et al. APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability. Cancer Discov 7:218-233 (2017). PubMed: 28069571
  • Wang S  et al. Densin-180 Controls the Trafficking and Signaling of L-Type Voltage-Gated Cav1.2 Ca2+Channels at Excitatory Synapses. J Neurosci 37:4679-4691 (2017). PubMed: 28363979
  • Wang D  et al. Investigation of the neuroprotective effects of a novel synthetic compound via the mitochondrial pathway. Mol Med Rep 16:1133-1138 (2017). PubMed: 28627694
  • Hu D  et al. miR-203 inhibits the expression of collagen-related genes and the proliferation of hepatic stellate cells through a SMAD3-dependent mechanism. Mol Med Rep 16:1248-1254 (2017). PubMed: 28586069
  • Wang J  et al. Regulation of type II collagen, matrix metalloproteinase-13 and cell proliferation by interleukin-1ß is mediated by curcumin via inhibition of NF-?B signaling in rat chondrocytes. Mol Med Rep 16:1837-1845 (2017). PubMed: 28627596
  • Yan J  et al. MicroRNA-503 inhibits the proliferation and invasion of breast cancer cells via targeting insulin-like growth factor 1 receptor. Mol Med Rep 16:1707-1714 (2017). PubMed: 28656281
  • Bugge M  et al. Surface Toll-like receptor 3 expression in metastatic intestinal epithelial cells induces inflammatory cytokine production and promotes invasiveness. J Biol Chem 292:15408-15425 (2017). PubMed: 28717003
  • Chen S  et al. Designer D-form self-assembling peptide scaffolds promote the proliferation and migration of rat bone marrow-derived mesenchymal stem cells. Int J Mol Med 40:679-688 (2017). PubMed: 28677805
  • Wang X  et al. Ganoderic acid A inhibits proliferation and invasion, and promotes apoptosis in human hepatocellular carcinoma cells. Mol Med Rep 16:3894-3900 (2017). PubMed: 28731159
  • Arai T  et al. Regulation of spindle and kinetochore-associated protein 1 by antitumor miR-10a-5p in renal cell carcinoma. Cancer Sci 108:2088-2101 (2017). PubMed: 28746769
  • Javadi A  et al. PTEN controls glandular morphogenesis through a juxtamembrane ß-Arrestin1/ARHGAP21 scaffolding complex. Elife 6:N/A (2017). PubMed: 28749339
  • Liu J  et al. Electroacupuncture attenuates learning and memory impairment via activation of a7nAChR-mediated anti-inflammatory activity in focal cerebral ischemia/reperfusion injured rats. Exp Ther Med 14:939-946 (2017). PubMed: 28810545
  • Zou Q  et al. MicroRNA-375 targets PAX6 and inhibits the viability, migration and invasion of human breast cancer MCF-7 cells. Exp Ther Med 14:1198-1204 (2017). PubMed: 28810579
  • Lian C  et al. Collagen type II is downregulated in the degenerative nucleus pulposus and contributes to the degeneration and apoptosis of human nucleus pulposus cells. Mol Med Rep 16:4730-4736 (2017). PubMed: 28791354
  • Korb E  et al. Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition. Cell 170:1209-1223.e20 (2017). PubMed: 28823556
  • Wang Z  et al. Suppressive effects of human fetal keratinocytes on the proliferation, differentiation and extracellular matrix synthesis of human hypertrophic scar fibroblasts in vitro. Mol Med Rep 16:5377-5385 (2017). PubMed: 28849177
  • Wang R  et al. Protective effects of heme oxygenase-1-transduced bone marrow-derived mesenchymal stem cells on reduced-size liver transplantation: Role of autophagy regulated by the ERK/mTOR signaling pathway. Int J Mol Med 40:1537-1548 (2017). PubMed: 28901391
  • Okato A  et al. Dual Strands of Pre-miR-149 Inhibit Cancer Cell Migration and Invasion through Targeting FOXM1 in Renal Cell Carcinoma. Int J Mol Sci 18:N/A (2017). PubMed: 28902136
  • Zhu C  et al. Evidence that CA3 is Underling the Comorbidity Between Pain and Depression and the Co-curation by Wu-Tou decoction in Neuropathic Pain. Sci Rep 7:11935 (2017). PubMed: 28931876
  • Cui YL  et al. Necroptosis as a potential therapeutic target in multiple organ dysfunction syndrome. Oncotarget 8:56980-56990 (2017). PubMed: 28915647
  • Ma W  et al. Identification of microRNAs involved in gefitinib resistance of non-small-cell lung cancer through the insulin-like growth factor receptor 1 signaling pathway. Exp Ther Med 14:2853-2862 (2017). PubMed: 28912847
  • Song W  et al. Quercetin inhibits angiogenesis-mediated human retinoblastoma growth by targeting vascular endothelial growth factor receptor. Oncol Lett 14:3343-3348 (2017). PubMed: 28927086
  • Yin J  et al. Role of miR-128 in hypertension-induced myocardial injury. Exp Ther Med 14:2751-2756 (2017). PubMed: 28928797
  • Huang ZJ  et al. NEDD4 promotes cell growth and migration via PTEN/PI3K/AKT signaling in hepatocellular carcinoma. Oncol Lett 14:2649-2656 (2017). PubMed: 28928809
  • Cheng P  et al. Molecular mechanisms of ampelopsin fromAmpelopsis megalophyllainduces apoptosis in HeLa cells. Oncol Lett 14:2691-2698 (2017). PubMed: 28928812
  • Feng F  et al. Downregulation of Rab27A contributes to metformin-induced suppression of breast cancer stem cells. Oncol Lett 14:2947-2953 (2017). PubMed: 28928832
  • Singh NN  et al. Activation of a cryptic 5' splice site reverses the impact of pathogenic splice site mutations in the spinal muscular atrophy gene. Nucleic Acids Res 45:12214-12240 (2017). PubMed: 28981879
  • Lin J  et al. MiR-203 inhibits estrogen-induced viability, migration and invasion of estrogen receptor a-positive breast cancer cells. Exp Ther Med 14:2702-2708 (2017). PubMed: 28962215
  • Shou X  et al. Baicalin Suppresses Hypoxia-Reoxygenation-Induced Arterial Endothelial Cell Apoptosis via Suppressing PKCd/p53 Signaling. Med Sci Monit 23:6057-6063 (2017). PubMed: 29272263
  • Wang J  et al. Protein arginylation targets alpha synuclein, facilitates normal brain health, and prevents neurodegeneration. Sci Rep 7:11323 (2017). WB . PubMed: 28900170
  • Markus-Koch A  et al. ADAM23 promotes neuronal differentiation of human neural progenitor cells. Cell Mol Biol Lett 22:16 (2017). WB . PubMed: 28828010
  • Ortega FE  et al. Adhesion to the host cell surface is sufficient to mediateListeria monocytogenesentry into epithelial cells. Mol Biol Cell 28:2945-2957 (2017). PubMed: 28877987
  • He Z  et al. Autophagy protects auditory hair cells against neomycin-induced damage. Autophagy 13:1884-1904 (2017). PubMed: 28968134
  • Koshizuka K  et al. Deep sequencing-based microRNA expression signatures in head and neck squamous cell carcinoma: dual strands of pre-miR-150 as antitumor miRNAs. Oncotarget 8:30288-30304 (2017). PubMed: 28415821
  • Luo Y  et al. Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis. Cell Res 27:352-372 (2017). PubMed: 28084332
  • Liu K  et al. The miR-124-p63 feedback loop modulates colorectal cancer growth. Oncotarget 8:29101-29115 (2017). PubMed: 28418858
  • Wiese M  et al. The ß-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner. Oncotarget 8:27300-27313 (2017). PubMed: 28460484
  • Siedlinski M  et al. Vascular transcriptome profiling identifies Sphingosine kinase 1 as a modulator of angiotensin II-induced vascular dysfunction. Sci Rep 7:44131 (2017). PubMed: 28276483
  • Lukas J  et al. Glucosylsphingosine Causes Hematological and Visceral Changes in Mice-Evidence for a Pathophysiological Role in Gaucher Disease. Int J Mol Sci 18:N/A (2017). WB . PubMed: 29053611
  • Shinmura K  et al. Mutation Spectrum Induced by 8-Bromoguanine, a Base Damaged by Reactive Brominating Species, in Human Cells. Oxid Med Cell Longev 2017:7308501 (2017). WB . PubMed: 29098062
  • Wang Y  et al. A systematic evaluation of microRNAs in regulating human hepatic CYP2E1. Biochem Pharmacol 138:174-184 (2017). WB ; Human . PubMed: 28438567
  • Levan J  et al. Human papillomavirus type 16 E6 and NFX1-123 mislocalize immune signaling proteins and downregulate immune gene expression in keratinocytes. PLoS One 12:e0187514 (2017). WB ; Human . PubMed: 29117186
  • Gustin JP  et al. GATA3 frameshift mutation promotes tumor growth in human luminal breast cancer cells and induces transcriptional changes seen in primary GATA3 mutant breast cancers. Oncotarget 8:103415-103427 (2017). WB . PubMed: 29262572
  • Abe Y  et al. Deep Phospho- and Phosphotyrosine Proteomics Identified Active Kinases and Phosphorylation Networks in Colorectal Cancer Cell Lines Resistant to Cetuximab. Sci Rep 7:10463 (2017). PubMed: 28874695
  • Jing W  et al. LCZ696 (Sacubitril/valsartan) ameliorates oxidative stress, inflammation, fibrosis and improves renal function beyond angiotensin receptor blockade in CKD. Am J Transl Res 9:5473-5484 (2017). WB . PubMed: 29312499
  • Liu L  et al. Hypoxia-inducible factor 1 mediates intermittent hypoxia-induced migration of human breast cancer MDA-MB-231 cells. Oncol Lett 14:7715-7722 (2017). PubMed: 29250173
  • Joly S  et al. Sphingosine 1-Phosphate Receptor 1 Modulates CNTF-Induced Axonal Growth and Neuroprotection in the Mouse Visual System. Neural Plast 2017:6818970 (2017). PubMed: 29234527
  • Zhang S  et al. hsa-miR-29c-3p regulates biological function of colorectal cancer by targeting SPARC. Oncotarget 8:104508-104524 (2017). PubMed: 29262657
  • Catanzaro G  et al. Loss of miR-107, miR-181c and miR-29a-3p Promote Activation of Notch2 Signaling in Pediatric High-Grade Gliomas (pHGGs). Int J Mol Sci 18:N/A (2017). PubMed: 29258209
  • Xie L  et al. The Expression of AQP5 and UTs in the Sweat Glands of Uremic Patients. Biomed Res Int 2017:8629783 (2017). PubMed: 29279852
  • Zahoor M  et al. Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss. Blood Adv 1:2656-2666 (2017). PubMed: 29296919
  • Chari A  et al. A phase 2 study of panobinostat with lenalidomide and weekly dexamethasone in myeloma. Blood Adv 1:1575-1583 (2017). PubMed: 29296798
  • Goldstein I  et al. Synergistic gene expression during the acute phase response is characterized by transcription factor assisted loading. Nat Commun 8:1849 (2017). PubMed: 29185442
  • Yi S  et al. miR-30c promotes Schwann cell remyelination following peripheral nerve injury. Neural Regen Res 12:1708-1715 (2017). PubMed: 29171437
  • Chen W  et al. MALAT1-miR-101-SOX9 feedback loop modulates the chemo-resistance of lung cancer cell to DDP via Wnt signaling pathway. Oncotarget 8:94317-94329 (2017). PubMed: 29212230
  • Lin MX  et al. Lobocrassin B Induces Apoptosis of Human Lung Cancer and Inhibits Tumor Xenograft Growth. Mar Drugs 15:N/A (2017). PubMed: 29207557
  • Martín-Maestro P  et al. Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease. Oxid Med Cell Longev 2017:9302761 (2017). PubMed: 29201274
  • Zhu Z  et al. Morinda Officinalis Polysaccharides Stimulate Hypothalamic GnRH Secretion in Varicocele Progression. Evid Based Complement Alternat Med 2017:9057959 (2017). PubMed: 29234440
  • Rocha M  et al. Modulation of fibronectin and laminin expression by Rhodium (II) citrate-coated maghemite nanoparticles in mice bearing breast tumor. Sci Rep 7:17904 (2017). PubMed: 29263369
  • Shi-Peng G  et al. TMED2 promotes epithelial ovarian cancer growth. Oncotarget 8:94151-94165 (2017). PubMed: 29212217
  • Gan L  et al. Reduced Endoplasmic Reticulum Stress-Mediated Autophagy Is Required for Leptin Alleviating Inflammation in Adipose Tissue. Front Immunol 8:1507 (2017). PubMed: 29250056
  • Zhang H  et al. An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis. Elife 6:N/A (2017). PubMed: 29140246
  • Olsen OE  et al. TGF-ß contamination of purified recombinant GDF15. PLoS One 12:e0187349 (2017). PubMed: 29161287
  • Zhang HH  et al. Role of 5-Aza-CdR in mitomycin-C chemosensitivity of T24 bladder cancer cells. Oncol Lett 14:5652-5656 (2017). PubMed: 29142609
  • Zhang T  et al. Value ofCNRIP1promoter methylation in colorectal cancer screening and prognosis assessment and its influence on the activity of cancer cells. Arch Med Sci 13:1281-1294 (2017). PubMed: 29181058
  • Xiao Y  et al. IGFBP-4 expression is adversely associated with lung cancer prognosis. Oncol Lett 14:6876-6880 (2017). PubMed: 29163706
  • Liu S  et al. Sirt1 regulates apoptosis and extracellular matrix degradation in resveratrol-treated osteoarthritis chondrocytes via the Wnt/ß-catenin signaling pathways. Exp Ther Med 14:5057-5062 (2017). PubMed: 29201214
  • Gao Z  et al. Molecular mechanism of miR-181b in heart disease due to pregnancy-induced hypertension syndrome. Exp Ther Med 14:2953-2959 (2017). WB . PubMed: 28912851
  • Han X  et al. Resveratrol increases nucleus pulposus matrix synthesis through activating the PI3K/Akt signaling pathway under mechanical compression in a disc organ culture. Biosci Rep 37:N/A (2017). PubMed: 29074559
  • Wu X  et al. Fucoidan elevates surface organic cation transporter 2 expression via upregulation of protein kinase A in uric acid nephropathy. Exp Ther Med 14:4153-4159 (2017). PubMed: 29104632
  • Degryse B  et al. Data on the regulation of moesin and merlin by the urokinase receptor (uPAR): Model explaining distal activation of integrins by uPAR. Data Brief 15:600-605 (2017). PubMed: 29085875
  • Gao T  et al. LncRNA HSP90AA1-IT1 promotes gliomas by targeting miR-885-5p-CDK2 pathway. Oncotarget 8:75284-75297 (2017). PubMed: 29088865
  • Shi WJ  et al. E6/E7 proteins are potential markers for the screening and diagnosis of cervical pre-cancerous lesions and cervical cancer in a Chinese population. Oncol Lett 14:6251-6258 (2017). PubMed: 29113275
  • Hu C  et al. High expression of Rab25 contributes to malignant phenotypes and biochemical recurrence in patients with prostate cancer after radical prostatectomy. Cancer Cell Int 17:45 (2017). PubMed: 28400705
  • Ruf S  et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy 13:486-505 (2017). PubMed: 28102733
  • Xu SC  et al. Bezafibrate Attenuates Pressure Overload-Induced Cardiac Hypertrophy and Fibrosis. PPAR Res 2017:5789714 (2017). PubMed: 28127304
  • Zhu Z  et al. HCV Induces Telomerase Reverse Transcriptase, Increases Its Catalytic Activity, and Promotes Caspase Degradation in Infected Human Hepatocytes. PLoS One 12:e0166853 (2017). PubMed: 28056029
  • Li H  et al. MicroRNA-17-5p inhibits proliferation and triggers apoptosis in non-small cell lung cancer by targeting transforming growth factor ß receptor 2. Exp Ther Med 13:2715-2722 (2017). PubMed: 28588663
  • Karijolich J  et al. Genome-wide mapping of infection-induced SINE RNAs reveals a role in selective mRNA export. Nucleic Acids Res 45:6194-6208 (2017). PubMed: 28334904
  • Peng T  et al. Centrosomal protein 55 activates NF-?B signalling and promotes pancreatic cancer cells aggressiveness. Sci Rep 7:5925 (2017). PubMed: 28724890
  • Grzelak CA  et al. Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease. PLoS One 12:e0171480 (2017). WB . PubMed: 28187190
  • Barry G  et al. The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states. Sci Rep 7:40127 (2017). WB . PubMed: 28054653
  • Zhu M  et al. Lnc-mg is a long non-coding RNA that promotes myogenesis. Nat Commun 8:14718 (2017). WB . PubMed: 28281528
  • Wang L  et al. Cannabinoid Receptor 1 Mediates Homing of Bone Marrow-Derived Mesenchymal Stem Cells Triggered by Chronic Liver Injury. J Cell Physiol 232:110-21 (2017). PubMed: 27028843
  • Yu N  et al. Anti-Diabetic Effects of Jiang Tang Xiao Ke Granule via PI3K/Akt Signalling Pathway in Type 2 Diabetes KKAy Mice. PLoS One 12:e0168980 (2017). Mouse . PubMed: 28045971
  • Bénit P  et al. Paradoxical Inhibition of Glycolysis by Pioglitazone Opposes the Mitochondriopathy Caused by AIF Deficiency. EBioMedicine 17:75-87 (2017). ICC/IF ; Mouse . PubMed: 28229909
  • Chen J  et al. Aggravated myocardial infarction-induced cardiac remodeling and heart failure in histamine-deficient mice. Sci Rep 7:44007 (2017). WB . PubMed: 28272448
  • Wang H  et al. MicroRNA-495 Inhibits Gastric Cancer Cell Migration and Invasion Possibly via Targeting High Mobility Group AT-Hook 2 (HMGA2). Med Sci Monit 23:640-648 (2017). WB ; Human . PubMed: 28159956
  • Weng M  et al. The E3 ubiquitin ligase NEDD4 is translationally upregulated and facilitates pancreatic cancer. Oncotarget 8:20288-20296 (2017). WB ; Human . PubMed: 28423617
  • Deng L  et al. Luteolin, a novel p90 ribosomal S6 kinase inhibitor, suppresses proliferation and migration in leukemia cells. Oncol Lett 13:1370-1378 (2017). WB ; Human . PubMed: 28454264
  • Corda G  et al. Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer. J Pathol 241:350-361 (2017). WB ; Human . PubMed: 27859262
  • Zheng C  et al. Gastrodin Inhibits Store-Operated Ca(2+) Entry and Alleviates Cardiac Hypertrophy. Front Pharmacol 8:222 (2017). WB ; Mouse . PubMed: 28487655
  • Sun N  et al. Inhibitory effect of dexamethasone on residual Lewis lung cancer cells in mice following palliative surgery. Oncol Lett 13:356-362 (2017). WB ; Mouse . PubMed: 28123567
  • Meng X  et al. Heterogeneous nuclear ribonucleoprotein A1 interacts with microRNA-34a to promote chondrogenic differentiation of mesenchymal stem cells. Am J Transl Res 9:1774-1782 (2017). WB ; Mouse . PubMed: 28469782
  • Chen M  et al. Isoquercetin activates the ERK1/2-Nrf2 pathway and protects against cerebral ischemia-reperfusion injury in vivo and in vitro. Exp Ther Med 13:1353-1359 (2017). WB ; Rat . PubMed: 28413477
  • Wei J  et al. Effect of captopril on radiation-induced TGF-ß1 secretion in EA.Hy926 human umbilical vein endothelial cells. Oncotarget 8:20842-20850 (2017). WB ; Human . PubMed: 28209920
  • Yan L  et al. Downregulation of microRNA-30d promotes cell proliferation and invasion by targeting LRH-1 in colorectal carcinoma. Int J Mol Med 39:1371-1380 (2017). WB ; Human . PubMed: 28440426
  • Wong JJ  et al. Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment. Nat Commun 8:15134 (2017). WB ; Mouse . PubMed: 28480880
  • Plantinga TS  et al. Rare NOX3 Variants Confer Susceptibility to Agranulocytosis During Thyrostatic Treatment of Graves' Disease. Clin Pharmacol Ther N/A:N/A (2017). Human . PubMed: 28486791
  • Chiang CF  et al. Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-?B signaling. Oncotarget 8:20706-20718 (2017). WB ; Human . PubMed: 28157701
  • Pellegrini L  et al. HMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma. Oncotarget 8:22649-22661 (2017). PubMed: 28186988
  • Hu J  et al. BMSC paracrine activity attenuates interleukin-1ß-induced inflammation and apoptosis in rat AF cells via inhibiting relative NF-?B signaling and the mitochondrial pathway. Am J Transl Res 9:79-89 (2017). WB ; Rat . PubMed: 28123635
  • van der Lelij P  et al. Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts. Elife 6:N/A (2017). Human . PubMed: 28691904
  • Wang J  et al. Antidiabetic activities of polysaccharides separated from Inonotus obliquus via the modulation of oxidative stress in mice with streptozotocin-induced diabetes. PLoS One 12:e0180476 (2017). WB ; Mouse . PubMed: 28662169
  • Crawford Parks TE  et al. Novel Roles for Staufen1 in Embryonal and Alveolar Rhabdomyosarcoma via c-myc-dependent and -independent events. Sci Rep 7:42342 (2017). PubMed: 28211476
  • Banerjee J  et al. Regulatory Roles of Anoctamin-6 in Human Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci 58:492-501 (2017). WB . PubMed: 28125837
  • Xu P  et al. Parvovirus B19 NS1 protein induces cell cycle arrest at G2-phase by activating the ATR-CDC25C-CDK1 pathway. PLoS Pathog 13:e1006266 (2017). PubMed: 28264028
  • Braga AC  et al. Inhibition of hepatitis C virus using siRNA targeted to the virus and Hsp90. Cell Stress Chaperones 22:113-122 (2017). PubMed: 27858224
  • Jiang L  et al. Identification of the vascular endothelial growth factor signalling pathway by quantitative proteomic analysis of rat condylar cartilage. FEBS Open Bio 7:44-53 (2017). WB . PubMed: 28097087
  • Cheng J  et al. Role of nuclear factor (erythroid-derived 2)-like 2 in the age-resistant properties of the glaucoma trabecular meshwork. Exp Ther Med 14:791-796 (2017). PubMed: 28673001
  • Zhang R  et al. SHH Protein Variance in the Limb Bud Is Constrained by Feedback Regulation and Correlates with Altered Digit Patterning. G3 (Bethesda) 7:851-858 (2017). WB . PubMed: 28131983
  • Tezze C  et al. Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence. Cell Metab 25:1374-1389.e6 (2017). PubMed: 28552492
  • Li Y  et al. MicroRNA-210 induces endothelial cell apoptosis by directly targeting PDK1 in the setting of atherosclerosis. Cell Mol Biol Lett 22:3 (2017). WB . PubMed: 28536634
  • Yuan Z  et al. Suppressive effect of microRNA-138 on the proliferation and invasion of osteosarcoma cells via targeting SIRT1. Exp Ther Med 13:3417-3423 (2017). PubMed: 28587420
  • Almalki SG  et al. MMP-2 and MMP-14 Silencing Inhibits VEGFR2 Cleavage and Induces the Differentiation of Porcine Adipose-Derived Mesenchymal Stem Cells to Endothelial Cells. Stem Cells Transl Med 6:1385-1398 (2017). WB ; Pig . PubMed: 28213979
  • He Y & Yu B MicroRNA-93 promotes cell proliferation by directly targeting P21 in osteosarcoma cells. Exp Ther Med 13:2003-2011 (2017). PubMed: 28565800
  • Stork CT  et al. Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage. Elife 5:N/A (2016). PubMed: 27552054
  • Zhu J  et al. Targeting survivin using a combination of miR-494 and survivin shRNA has synergistic effects on the suppression of prostate cancer growth. Mol Med Rep 13:1602-10 (2016). WB . PubMed: 26718651
  • Banushi B  et al. Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis. Nat Commun 7:12111 (2016). PubMed: 27435297
  • Gorres KL  et al. Valpromide Inhibits Lytic Cycle Reactivation of Epstein-Barr Virus. MBio 7:e00113 (2016). WB . PubMed: 26933051
  • Ferreyra Solari NE  et al. The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem-like Properties in Glioblastoma That Contribute to Tumorigenesis. Cancer Res 76:5383-94 (2016). PubMed: 27406830
  • Henriksen S  et al. The Presumed Polyomavirus Viroporin VP4 of Simian Virus 40 or Human BK Polyomavirus Is Not Required for Viral Progeny Release. J Virol 90:10398-10413 (2016). PubMed: 27630227
  • He R  et al. Different effect of testosterone and oestrogen on urinary excretion of metformin via regulating OCTs and MATEs expression in the kidney of mice. J Cell Mol Med 20:2309-2317 (2016). WB . PubMed: 27469532
  • Zoladz JA  et al. Mechanisms of Attenuation of Pulmonary V'O2 Slow Component in Humans after Prolonged Endurance Training. PLoS One 11:e0154135 (2016). WB . PubMed: 27104346
  • Liu Z  et al. MicroRNA-101 suppresses migration and invasion via targeting vascular endothelial growth factor-C in hepatocellular carcinoma cells. Oncol Lett 11:433-438 (2016). PubMed: 26870229
  • Zhang K  et al. Elevated Transforming Growth Factor-ß2 in the Aqueous Humor: A Possible Explanation for High Rate of Capsular Contraction Syndrome in High Myopia. J Ophthalmol 2016:5438676 (2016). PubMed: 26942002
  • Kotsantis P  et al. Increased global transcription activity as a mechanism of replication stress in cancer. Nat Commun 7:13087 (2016). WB . PubMed: 27725641
  • Dupont T  et al. Selective targeting of BCL6 induces oncogene addiction switching to BCL2 in B-cell lymphoma. Oncotarget 7:3520-32 (2016). WB . PubMed: 26657288
  • Jia Q  et al. Downregulation of YAP-dependent Nupr1 promotes tumor-repopulating cell growth in soft matrices. Oncogenesis 5:e220 (2016). WB . PubMed: 27089143
  • Wike CL  et al. Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis. Elife 5:e11402 (2016). PubMed: 26878753
  • Ahadome SD  et al. Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring. JCI Insight 1:e87001 (2016). PubMed: 27699226
  • Girouard MP  et al. RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress. PLoS One 11:e0168641 (2016). PubMed: 27992599
  • Bondy-Chorney E  et al. Staufen1 Regulates Multiple Alternative Splicing Events either Positively or Negatively in DM1 Indicating Its Role as a Disease Modifier. PLoS Genet 12:e1005827 (2016). WB . PubMed: 26824521
  • Ott C  et al. Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts. Redox Biol 10:266-273 (2016). WB . PubMed: 27825071
  • Haeger SM  et al. Smad4 loss promotes lung cancer formation but increases sensitivity to DNA topoisomerase inhibitors. Oncogene 35:577-586 (2016). PubMed: 25893305
  • Sirianni A  et al. Mitochondria mediate septin cage assembly to promote autophagy of Shigella. EMBO Rep 17:1029-43 (2016). PubMed: 27259462
  • Illendula A  et al. Small Molecule Inhibitor of CBFß-RUNX Binding for RUNX Transcription Factor Driven Cancers. EBioMedicine 8:117-31 (2016). WB . PubMed: 27428424
  • Sathiyamoorthy K  et al. Structural basis for Epstein-Barr virus host cell tropism mediated by gp42 and gHgL entry glycoproteins. Nat Commun 7:13557 (2016). PubMed: 27929061
  • Reeg S  et al. The molecular chaperone Hsp70 promotes the proteolytic removal of oxidatively damaged proteins by the proteasome. Free Radic Biol Med 99:153-166 (2016). WB . PubMed: 27498116
  • D'Orsi B  et al. Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury. J Neurosci 36:4564-78 (2016). PubMed: 27098698
  • Echeverría PC  et al. A Remodeled Hsp90 Molecular Chaperone Ensemble with the Novel Cochaperone Aarsd1 Is Required for Muscle Differentiation. Mol Cell Biol 36:1310-21 (2016). PubMed: 26884463
  • Guo H  et al. Expression and clinical significance of Apollon in renal carcinoma. Oncol Lett 12:5129-5135 (2016). WB . PubMed: 28105219
  • Shao Q  et al. Transcriptome sequencing of neurologic diseases associated genes in HHV-6A infected human astrocyte. Oncotarget 7:48070-48080 (2016). WB . PubMed: 27344170
  • Nanni SB  et al. Impact of Concanavalin-A-Mediated Cytoskeleton Disruption on Low-Density Lipoprotein Receptor-Related Protein-1 Internalization and Cell Surface Expression in Glioblastomas. Biomark Cancer 8:77-87 (2016). Human . PubMed: 27226736
  • Guo Q  et al. Controlled Heat Stress Promotes Myofibrillogenesis during Myogenesis. PLoS One 11:e0166294 (2016). WB ; Mouse . PubMed: 27824934
  • Sullivan PM  et al. The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway. Acta Neuropathol Commun 4:51 (2016). PubMed: 27193190
  • Wang Y  et al. Tricholoma matsutake Aqueous Extract Induces Hepatocellular Carcinoma Cell Apoptosis via Caspase-Dependent Mitochondrial Pathway. Biomed Res Int 2016:9014364 (2016). WB . PubMed: 28018916
  • Wang Y  et al. MicroRNA-142-3p inhibits hypoxia/reoxygenation-induced apoptosis and fibrosis of cardiomyocytes by targeting high mobility group box 1. Int J Mol Med 38:1377-1386 (2016). WB ; Mouse . PubMed: 28025989
  • Chow EC  et al. Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters. Drug Metab Dispos 44:1524-35 (2016). WB ; Human . PubMed: 27342868
  • Dass RA  et al. Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I. PLoS Genet 12:e1006217 (2016). PubMed: 27500936
  • Pavel M  et al. CCT complex restricts neuropathogenic protein aggregation via autophagy. Nat Commun 7:13821 (2016). WB . PubMed: 27929117
  • Kurozumi A  et al. Tumor-suppressive microRNA-223 inhibits cancer cell migration and invasion by targeting ITGA3/ITGB1 signaling in prostate cancer. Cancer Sci 107:84-94 (2016). WB ; Human . PubMed: 26509963
  • Ando R  et al. The Transcription Factor Bach2 Is Phosphorylated at Multiple Sites in Murine B Cells but a Single Site Prevents Its Nuclear Localization. J Biol Chem 291:1826-40 (2016). WB ; Mouse . PubMed: 26620562
  • Zhang H  et al. Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome. PLoS One 11:e0167454 (2016). WB, ICC/IF ; Human . PubMed: 27907109
  • Zhang X  et al. MicroRNA-195 suppresses colorectal cancer cells proliferation via targeting FGF2 and regulating Wnt/ß-catenin pathway. Am J Cancer Res 6:2631-2640 (2016). WB ; Human . PubMed: 27904776
  • Sverdlov AL  et al. Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. J Am Heart Assoc 5:N/A (2016). WB ; Mouse . PubMed: 26755553
  • Kapeli K  et al. Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. Nat Commun 7:12143 (2016). WB . PubMed: 27378374
  • Dalle Pezze P  et al. A systems study reveals concurrent activation of AMPK and mTOR by amino acids. Nat Commun 7:13254 (2016). PubMed: 27869123
  • Wang S  et al. PBX3 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition. Oncol Lett 12:3485-3491 (2016). WB ; Human . PubMed: 27900025
  • Yang X  et al. MicroRNA-133b inhibits the migration and invasion of non small cell lung cancer cells via targeting FSCN1. Oncol Lett 12:3619-3625 (2016). WB . PubMed: 27900045
  • Sturdivant NM  et al. Acetazolamide Mitigates Astrocyte Cellular Edema Following Mild Traumatic Brain Injury. Sci Rep 6:33330 (2016). WB . PubMed: 27623738
  • Huang H  et al. Microcystin-LR Induced Apoptosis in Rat Sertoli Cells via the Mitochondrial Caspase-Dependent Pathway: Role of Reactive Oxygen Species. Front Physiol 7:397 (2016). PubMed: 27667976
  • Lewis WR  et al. Mutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human Disease. PLoS Genet 12:e1006220 (2016). WB . PubMed: 27472056
  • Wemhoff S  et al. DNA Damage Responses Are Induced by tRNA Anticodon Nucleases and Hygromycin B. PLoS One 11:e0157611 (2016). PubMed: 27472060
  • Frendo-Cumbo S  et al. Beneficial effects of combined resveratrol and metformin therapy in treating diet-induced insulin resistance. Physiol Rep 4:N/A (2016). PubMed: 27482073
  • Okato A  et al. Direct regulation of LAMP1 by tumor-suppressive microRNA-320a in prostate cancer. Int J Oncol 49:111-22 (2016). WB ; Human . PubMed: 27212625
  • Conte A  et al. Convergent Effects of Resveratrol and PYK2 on Prostate Cells. Int J Mol Sci 17:N/A (2016). PubMed: 27649143
  • Kashyap T  et al. Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-?B deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death. Oncotarget 7:78883-78895 (2016). WB ; Human . PubMed: 27713151
  • Franco A  et al. Correcting mitochondrial fusion by manipulating mitofusin conformations. Nature 540:74-79 (2016). WB . PubMed: 27775718
  • Tao J  et al. Tea polyphenols protect against ischemia/reperfusion-induced liver injury in mice through anti-oxidative and anti-apoptotic properties. Exp Ther Med 12:3433-3439 (2016). WB ; Mouse . PubMed: 27882175
  • Zhao JL  et al. B7-H3 protein expression in a murine model of osteosarcoma. Oncol Lett 12:383-386 (2016). WB . PubMed: 27347155
  • Hua W  et al. Mechanical stretch regulates microRNA expression profile via NF-?B activation in C2C12 myoblasts. Mol Med Rep 14:5084-5092 (2016). WB ; Mouse . PubMed: 27840929
  • Zhang W  et al. Effect of Yi-nao-jie-yu decoction on ?-aminobutyric acid type A receptor in the hippocampus and serum inflammatory factors in a rat model of poststroke anxiety. Neuropsychiatr Dis Treat 12:2827-2837 (2016). WB ; Rat . PubMed: 27843317
  • Cao Q  et al. MicroRNA-7 inhibits cell proliferation, migration and invasion in human non-small cell lung cancer cells by targeting FAK through ERK/MAPK signaling pathway. Oncotarget 7:77468-77481 (2016). WB ; Human . PubMed: 27764812
  • Gao Y  et al. Neuroprotective effects of polydatin against mitochondrial-dependent apoptosis in the rat cerebral cortex following ischemia/reperfusion injury. Mol Med Rep 14:5481-5488 (2016). WB ; Rat . PubMed: 27840959
  • Aherne ST  et al. Altered expression of mir-222 and mir-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein expression. Int J Mol Med 38:433-45 (2016). WB . PubMed: 27353001
  • Hurtado-Alvarado G  et al. A2A Adenosine Receptor Antagonism Reverts the Blood-Brain Barrier Dysfunction Induced by Sleep Restriction. PLoS One 11:e0167236 (2016). WB ; Rat . PubMed: 27893847
  • Zhang Y  et al. MicroRNA-135b has a neuroprotective role via targeting of ß-site APP-cleaving enzyme 1. Exp Ther Med 12:809-814 (2016). WB ; Human . PubMed: 27446280
  • Huang R  et al. The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer. Oncotarget 7:4695-711 (2016). WB ; Human . PubMed: 26683361
  • Orzalli MH  et al. Relative Contributions of Herpes Simplex Virus 1 ICP0 and vhs to Loss of Cellular IFI16 Vary in Different Human Cell Types. J Virol 90:8351-9 (2016). PubMed: 27412599
  • Johansen AK  et al. The serotonin transporter promotes a pathological estrogen metabolic pathway in pulmonary hypertension via cytochrome P450 1B1. Pulm Circ 6:82-92 (2016). WB . PubMed: 27162617
  • Roussa E  et al. The membrane trafficking and functionality of the K+-Cl- co-transporter KCC2 is regulated by TGF-ß2. J Cell Sci 129:3485-98 (2016). Mouse . PubMed: 27505893
  • Li D  et al. Procaine Attenuates Pain Behaviors of Neuropathic Pain Model Rats Possibly via Inhibiting JAK2/STAT3. Biomol Ther (Seoul) 24:489-94 (2016). PubMed: 27530113
  • Han Z  et al. ITCH E3 Ubiquitin Ligase Interacts with Ebola Virus VP40 To Regulate Budding. J Virol 90:9163-71 (2016). PubMed: 27489272
  • Li W  et al. Preliminary in vitro and in vivo assessment of a new targeted inhibitor for choroidal neovascularization in age-related macular degeneration. Drug Des Devel Ther 10:3415-3423 (2016). WB ; Human . PubMed: 27799741
  • Zhang GM  et al. MicroRNA-126 inhibits tumor cell invasion and metastasis by downregulating ROCK1 in renal cell carcinoma. Mol Med Rep 13:5029-2036 (2016). WB ; Human . PubMed: 27108693
  • Dave JM  et al. Hic-5 mediates the initiation of endothelial sprouting by regulating a key surface metalloproteinase. J Cell Sci 129:743-56 (2016). WB ; Human . PubMed: 26769900
  • Pei JF  et al. Human paraoxonase gene cluster overexpression alleviates angiotensin II-induced cardiac hypertrophy in mice. Sci China Life Sci 59:1115-1122 (2016). PubMed: 27578362
  • Soliman ML  et al. Caffeine Blocks HIV-1 Tat-Induced Amyloid Beta Production and Tau Phosphorylation. J Neuroimmune Pharmacol N/A:N/A (2016). PubMed: 27629410
  • Wang P  et al. Paeoniflorin ameliorates acute necrotizing pancreatitis and pancreatitis-induced acute renal injury. Mol Med Rep 14:1123-31 (2016). Rat . PubMed: 27279569
  • Surtees R  et al. Heat Shock Protein 70 Family Members Interact with Crimean-Congo Hemorrhagic Fever Virus and Hazara Virus Nucleocapsid Proteins and Perform a Functional Role in the Nairovirus Replication Cycle. J Virol 90:9305-16 (2016). PubMed: 27512070
  • Jansen C  et al. The coiled-coil domain of zebrafish TRPM7 regulates Mg·nucleotide sensitivity. Sci Rep 6:33459 (2016). PubMed: 27628598
  • Pérez-Cañamás A  et al. Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease. Mol Psychiatry N/A:N/A (2016). PubMed: 27620840
  • Nam EJ  et al. Robust Therapeutic Efficacy of Matrix Metalloproteinase-2-Cleavable Fas-1-RGD Peptide Complex in Chronic Inflammatory Arthritis. PLoS One 11:e0164102 (2016). PubMed: 27741237
  • Angelini C  et al. Lipolysis and lipophagy in lipid storage myopathies. Biochim Biophys Acta 1862:1367-73 (2016). PubMed: 27085974
  • Kaneko Y  et al. Oxytocin modulates GABAAR subunits to confer neuroprotection in stroke in vitro. Sci Rep 6:35659 (2016). WB ; Rat . PubMed: 27767042
  • Komatsu Y  et al. IRF1 Downregulation by Ras/MEK Is Independent of Translational Control of IRF1 mRNA. PLoS One 11:e0160529 (2016). PubMed: 27508303
  • Yao CJ  et al. Activation of p53/miR-34a Tumor Suppressor Axis by Chinese Herbal Formula JP-1 in A549 Lung Adenocarcinoma Cells. Evid Based Complement Alternat Med 2016:5989681 (2016). WB ; Human . PubMed: 28074102
  • Lanier MH  et al. Cell Migration and Invadopodia Formation Require a Membrane-binding Domain of CARMIL2. J Biol Chem 291:1076-91 (2016). PubMed: 26578515
  • Oza J  et al. A Novel Role of Chromodomain Protein CBX8 in DNA Damage Response. J Biol Chem 291:22881-22893 (2016). PubMed: 27555324
  • Gaponova AV  et al. A Novel HSP90 Inhibitor-Drug Conjugate to SN38 Is Highly Effective in Small Cell Lung Cancer. Clin Cancer Res 22:5120-5129 (2016). PubMed: 27267850
  • Song Y  et al. Enlargement of the Axial Length and Altered Ultrastructural Features of the Sclera in a Mutant Lumican Transgenic Mouse Model. PLoS One 11:e0163165 (2016). WB ; Mouse . PubMed: 27711221
  • Akhade VS  et al. Mechanism of Wnt signaling induced down regulation of mrhl long non-coding RNA in mouse spermatogonial cells. Nucleic Acids Res 44:387-401 (2016). PubMed: 26446991
  • Martin GG  et al. Female Mice are Resistant to Fabp1 Gene Ablation-Induced Alterations in Brain Endocannabinoid Levels. Lipids N/A:N/A (2016). WB ; Mouse . PubMed: 27450559
  • Wild T  et al. The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity. Cell Rep 14:1829-40 (2016). WB ; Human . PubMed: 26904940
  • Yang LX  et al. Ginsenoside Rd Attenuates DNA Damage by Increasing Expression of DNA Glycosylase Endonuclease VIII-like Proteins after Focal Cerebral Ischemia. Chin Med J (Engl) 129:1955-62 (2016). WB ; Rat . PubMed: 27503022
  • Snider NT  et al. Ethanol and Acetaminophen Synergistically Induce Hepatic Aggregation and TCH346-Insensitive Nuclear Translocation of GAPDH. PLoS One 11:e0160982 (2016). Mouse . PubMed: 27513663
  • Ilie A  et al. A Christianson syndrome-linked deletion mutation (?(287)ES(288)) in SLC9A6 disrupts recycling endosomal function and elicits neurodegeneration and cell death. Mol Neurodegener 11:63 (2016). PubMed: 27590723
  • Chen Z  et al. Suppressive effect of formononetin on platelet-derived growth factor-BB-stimulated proliferation and migration of vascular smooth muscle cells. Exp Ther Med 12:1901-1907 (2016). Human . PubMed: 27588108
  • Yi L  et al. Involvement of calreticulin in cell proliferation, invasion and differentiation in diallyl disulfide-treated HL-60 cells. Oncol Lett 12:1861-1867 (2016). Human . PubMed: 27588133
  • Salzman DW  et al. miR-34 activity is modulated through 5'-end phosphorylation in response to DNA damage. Nat Commun 7:10954 (2016). WB ; Human . PubMed: 26996824
  • Luo HT  et al. Effects of pramipexole treatment on the a-synuclein content in serum exosomes of Parkinson's disease patients. Exp Ther Med 12:1373-1376 (2016). WB ; Human . PubMed: 27588058
  • Fan Y  et al. Increased expression of FERM domain-containing 4A protein is closely associated with the development of rectal cancer. Exp Ther Med 11:421-426 (2016). PubMed: 26893625
  • Podmirseg SR  et al. Caspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasion. Oncogene 35:4580-90 (2016). PubMed: 26829051
  • Hwang SJ  et al. Ubiquitin-specific protease 4 controls metastatic potential through ß-catenin stabilization in brain metastatic lung adenocarcinoma. Sci Rep 6:21596 (2016). WB . PubMed: 26883469
  • Louis AG  et al. Common variable immunodeficiency associated with microdeletion of chromosome 1q42.1-q42.3 and inositol 1,4,5-trisphosphate kinase B (ITPKB) deficiency. Clin Transl Immunology 5:e59 (2016). WB . PubMed: 26900472
  • De Maio FA  et al. The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing. PLoS Pathog 12:e1005841 (2016). PubMed: 27575636
  • Hwang HW  et al. PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage. Cell Rep 15:423-35 (2016). PubMed: 27050522
  • Nejedla M  et al. Profilin connects actin assembly with microtubule dynamics. Mol Biol Cell 27:2381-93 (2016). PubMed: 27307590
  • Duran CL  et al. NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-?B pathway. Oncogenesis 5:e231 (2016). PubMed: 27270613
  • Groeneveld MP  et al. Acute knockdown of the insulin receptor or its substrates Irs1 and 2 in 3T3-L1 adipocytes suppresses adiponectin production. Sci Rep 6:21105 (2016). WB . PubMed: 26888756
  • Bento CF  et al. The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway. Nat Commun 7:11803 (2016). PubMed: 27278822
  • MacLeod AK  et al. Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer. Br J Cancer 115:1530-1539 (2016). PubMed: 27824809
  • Wike CL  et al. Excess free histone H3 localizes to centrosomes for proteasome-mediated degradation during mitosis in metazoans. Cell Cycle 15:2216-2225 (2016). PubMed: 27248858
  • Gao Y  et al. Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells. Sci Rep 6:28589 (2016). PubMed: 27358069
  • Martínez-Pizarro A  et al. Endoplasmic Reticulum Stress and Autophagy in Homocystinuria Patients with Remethylation Defects. PLoS One 11:e0150357 (2016). WB . PubMed: 26959487
  • Chen Y  et al. MicroRNA-138 suppresses proliferation, invasion and glycolysis in malignant melanoma cells by targeting HIF-1a. Exp Ther Med 11:2513-2518 (2016). PubMed: 27284341
  • Wan X  et al. Elucidating a molecular mechanism that the deterioration of porcine meat quality responds to increased cortisol based on transcriptome sequencing. Sci Rep 6:36589 (2016). WB . PubMed: 27833113
  • Lebensohn AM  et al. Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling. Elife 5:N/A (2016). WB . PubMed: 27996937
  • Seo J  et al. Oxidative Stress Triggers Body-Wide Skipping of Multiple Exons of the Spinal Muscular Atrophy Gene. PLoS One 11:e0154390 (2016). WB . PubMed: 27111068
  • Catanzaro G  et al. MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs. Stem Cells Int 2016:2683042 (2016). PubMed: 26880947
  • Dachtler J  et al. Missense mutation in DISC1 C-terminal coiled-coil has GSK3ß signaling and sex-dependent behavioral effects in mice. Sci Rep 6:18748 (2016). PubMed: 26728762
  • Jia W  et al. Upregulated ATF6 contributes to chronic intermittent hypoxia-afforded protection against myocardial ischemia/reperfusion injury. Int J Mol Med 37:1199-208 (2016). WB . PubMed: 27035093
  • Li N  et al. Overexpression of plastin 3 in Sertoli cells disrupts actin microfilament bundle homeostasis and perturbs the tight junction barrier. Spermatogenesis 6:e1206353 (2016). PubMed: 27559491
  • Patel KR  et al. Mast cell-derived neurotrophin 4 mediates allergen-induced airway hyperinnervation in early life. Mucosal Immunol 9:1466-1476 (2016). PubMed: 26860818
  • Deguise MO  et al. Differential induction of muscle atrophy pathways in two mouse models of spinal muscular atrophy. Sci Rep 6:28846 (2016). WB . PubMed: 27349908
  • Sharma M  et al. Preparation of the Human Cytomegalovirus Nuclear Egress Complex and Associated Proteins. Methods Enzymol 569:517-26 (2016). PubMed: 26778574
  • Stoszko M  et al. Small Molecule Inhibitors of BAF; A Promising Family of Compounds in HIV-1 Latency Reversal. EBioMedicine 3:108-21 (2016). WB . PubMed: 26870822
  • Pang X  et al. Role of miR-145 in chronic constriction injury in rats. Exp Ther Med 12:4121-4127 (2016). PubMed: 28105140
  • Rogalska ME  et al. Therapeutic activity of modified U1 core spliceosomal particles. Nat Commun 7:11168 (2016). PubMed: 27041075
  • Kang R  et al. Knockdown of PSCA induces EMT and decreases metastatic potentials of the human prostate cancer DU145 cells. Cancer Cell Int 16:20 (2016). PubMed: 26981049
  • Li P  et al. Surgical removal and controlled trypsinization of the outer annulus fibrosus improves the bioactivity of the nucleus pulposus in a disc bioreactor culture. BMC Musculoskelet Disord 17:133 (2016). PubMed: 27000557
  • Zhang W  et al. Effect of Jian-Pi-Zhi-Dong Decoction on striatal glutamate and ?-aminobutyric acid levels detected using microdialysis in a rat model of Tourette syndrome. Neuropsychiatr Dis Treat 12:1233-42 (2016). WB . PubMed: 27279743
  • Chen R  et al. MicroRNA-93 promotes the malignant phenotypes of human glioma cells and induces their chemoresistance to temozolomide. Biol Open 5:669-77 (2016). WB . PubMed: 27185265
  • Chen X  et al. Role of Endolysosomes in Skeletal Muscle Pathology Observed in a Cholesterol-Fed Rabbit Model of Alzheimer's Disease. Front Aging Neurosci 8:129 (2016). WB . PubMed: 27375475
  • Scheckel C  et al. Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain. Elife 5:N/A (2016). WB . PubMed: 26894958
  • Kurozumi A  et al. Regulation of the collagen cross-linking enzymes LOXL2 and PLOD2 by tumor-suppressive microRNA-26a/b in renal cell carcinoma. Int J Oncol 48:1837-46 (2016). WB . PubMed: 26983694
  • Zanos P  et al. NMDAR inhibition-independent antidepressant actions of ketamine metabolites. Nature 533:481-6 (2016). WB . PubMed: 27144355
  • Ye L  et al. Cardiomyocytes in Young Infants With Congenital Heart Disease: a Three-Month Window of Proliferation. Sci Rep 6:23188 (2016). WB . PubMed: 26976548
  • Sakakibara Y  et al. Effects of Phenobarbital on Expression of UDP-Glucuronosyltransferase 1a6 and 1a7 in Rat Brain. Drug Metab Dispos 44:370-7 (2016). PubMed: 26684499
  • Zhao X  et al. MicroRNA-126 inhibits the migration and invasion of endometrial cancer cells by targeting insulin receptor substrate 1. Oncol Lett 11:1207-1212 (2016). PubMed: 26893720
  • Hou S  et al. Mechanism of Mitochondrial Connexin43's Protection of the Neurovascular Unit under Acute Cerebral Ischemia-Reperfusion Injury. Int J Mol Sci 17:N/A (2016). PubMed: 27164087
  • Fu B  et al. GRAM domain-containing protein 1A (GRAMD1A) promotes the expansion of hepatocellular carcinoma stem cell and hepatocellular carcinoma growth through STAT5. Sci Rep 6:31963 (2016). WB . PubMed: 27585821
  • Wei WY  et al. Pioglitazone Protected against Cardiac Hypertrophy via Inhibiting AKT/GSK3ß and MAPK Signaling Pathways. PPAR Res 2016:9174190 (2016). PubMed: 27110236
  • Kupka S  et al. SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. Cell Rep 16:2271-80 (2016). WB . PubMed: 27545878
  • Boada-Romero E  et al. The T300A Crohn's disease risk polymorphism impairs function of the WD40 domain of ATG16L1. Nat Commun 7:11821 (2016). WB . PubMed: 27273576
  • Pawar K  et al. Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy. Sci Rep 6:19416 (2016). PubMed: 26757825
  • Zhang ZZ  et al. Long non-coding RNA LINC00628 functions as a gastric cancer suppressor via long-range modulating the expression of cell cycle related genes. Sci Rep 6:27435 (2016). WB . PubMed: 27272474
  • Gc JB  et al. Interdomain salt-bridges in the Ebola virus protein VP40 and their role in domain association and plasma membrane localization. Protein Sci 25:1648-58 (2016). WB . PubMed: 27328459
  • Chu J  et al. Translation Inhibition by Rocaglates Is Independent of eIF4E Phosphorylation Status. Mol Cancer Ther 15:136-41 (2016). PubMed: 26586722
  • Mudannayake JM  et al. Transcriptional activity of novel ALDH1L1 promoters in the rat brain following AAV vector-mediated gene transfer. Mol Ther Methods Clin Dev 3:16075 (2016). PubMed: 27990448
  • Li P  et al. Osmolarity affects matrix synthesis in the nucleus pulposus associated with the involvement of MAPK pathways: A study of ex vivo disc organ culture system. J Orthop Res 34:1092-100 (2016). WB ; Pig . PubMed: 26576043
  • Awais R  et al. p63 is required beside p53 for PERP-mediated apoptosis in uveal melanoma. Br J Cancer 115:983-992 (2016). WB . PubMed: 27584665
  • Liu M  et al. Hyperamylinemia Increases IL-1ß Synthesis in the Heart via Peroxidative Sarcolemmal Injury. Diabetes 65:2772-83 (2016). PubMed: 27335231
  • Lou J  et al. Type III Transforming Growth Factor-ß Receptor Drives Cardiac Hypertrophy Through ß-Arrestin2-Dependent Activation of Calmodulin-Dependent Protein Kinase II. Hypertension 68:654-66 (2016). PubMed: 27432858
  • van Geldermalsen M  et al. ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer. Oncogene 35:3201-8 (2016). PubMed: 26455325
  • Martin GG  et al. Fabp-1 gene ablation impacts brain endocannabinoid system in male mice. J Neurochem : (2016). PubMed: 27167970
  • Memme JM  et al. Chronology of UPR activation in skeletal muscle adaptations to chronic contractile activity. Am J Physiol Cell Physiol 310:C1024-36 (2016). PubMed: 27122157
  • Li YC  et al. Identification of NR0B1 as a novel androgen receptor co-repressor in mouse Sertoli cells. Int J Mol Med 38:853-60 (2016). PubMed: 27431683
  • Holle AW  et al. High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation. Integr Biol (Camb) 8:1049-1058 (2016). PubMed: 27723854
  • Loi S  et al. RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors. Clin Cancer Res 22:1499-509 (2016). PubMed: 26515496
  • Goto Y  et al. The microRNA signature of patients with sunitinib failure: regulation of UHRF1 pathways by microRNA-101 in renal cell carcinoma. Oncotarget 7:59070-59086 (2016). PubMed: 27487138
  • Cerveró C  et al. Chronic Treatment with the AMPK Agonist AICAR Prevents Skeletal Muscle Pathology but Fails to Improve Clinical Outcome in a Mouse Model of Severe Spinal Muscular Atrophy. Neurotherapeutics 13:198-216 (2016). PubMed: 26582176
  • Huang J  et al. Postponing the Hypoglycemic Response to Partial Hepatectomy Delays Mouse Liver Regeneration. Am J Pathol 186:587-99 (2016). PubMed: 26772417
  • Goto Y  et al. Regulation of E3 ubiquitin ligase-1 (WWP1) by microRNA-452 inhibits cancer cell migration and invasion in prostate cancer. Br J Cancer 114:1135-44 (2016). PubMed: 27070713
  • Kurkinen KM  et al. SEPT8 modulates ß-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1. J Cell Sci 129:2224-38 (2016). PubMed: 27084579
  • Deevi RK  et al. Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype. Oncotarget 7:49042-49064 (2016). PubMed: 27119498
  • Wang JY  et al. MicroRNA-23b regulates nasopharyngeal carcinoma cell proliferation and metastasis by targeting E-cadherin. Mol Med Rep 14:537-43 (2016). PubMed: 27150436
  • Hamilton JP  et al. Activation of liver X receptor/retinoid X receptor pathway ameliorates liver disease in Atp7B(-/-) (Wilson disease) mice. Hepatology 63:1828-41 (2016). PubMed: 26679751
  • Eliades P  et al. A novel multi-CDK inhibitor P1446A-05 restricts melanoma growth and produces synergistic effects in combination with MAPK pathway inhibitors. Cancer Biol Ther 17:778-84 (2016). PubMed: 26810603
  • Hahn YK  et al. Central HIV-1 Tat exposure elevates anxiety and fear conditioned responses of male mice concurrent with altered mu-opioid receptor-mediated G-protein activation and ß-arrestin 2 activity in the forebrain. Neurobiol Dis 92:124-36 (2016). PubMed: 26845176
  • Djamali A  et al. Nox2 and Cyclosporine-Induced Renal Hypoxia. Transplantation 100:1198-210 (2016). PubMed: 26950727
  • McFarland BC  et al. Loss of SOCS3 in myeloid cells prolongs survival in a syngeneic model of glioma. Oncotarget 7:20621-35 (2016). PubMed: 26967393
  • Joly S & Pernet V Sphingosine 1-phosphate receptor 1 is required for retinal ganglion cell survival after optic nerve trauma. J Neurochem 138:571-86 (2016). PubMed: 27309795
  • Yamanoi K  et al. Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer. Oncotarget 7:47620-47636 (2016). PubMed: 27323405
  • Wu HJ  et al. Microarray Expression Profile of Circular RNAs in Heart Tissue of Mice with Myocardial Infarction-Induced Heart Failure. Cell Physiol Biochem 39:205-16 (2016). PubMed: 27336675
  • Böhm A  et al. TGF-ß Contributes to Impaired Exercise Response by Suppression of Mitochondrial Key Regulators in Skeletal Muscle. Diabetes 65:2849-61 (2016). PubMed: 27358493
  • Magalhaes J  et al. Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease. Hum Mol Genet 25:3432-3445 (2016). PubMed: 27378698
  • Ahn J  et al. Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer. Oncotarget 7:63252-63260 (2016). PubMed: 27533081
  • Baranowska K  et al. Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells. Oncotarget 7:70845-70856 (2016). PubMed: 27683126
  • Jackson RJ  et al. Human tau increases amyloid ß plaque size but not amyloid ß-mediated synapse loss in a novel mouse model of Alzheimer's disease. Eur J Neurosci 44:3056-3066 (2016). PubMed: 27748574
  • Shu Q  et al. Involvement of eIF6 in external mechanical stretch-mediated murine dermal fibroblast function via TGF-ß1 pathway. Sci Rep 6:36075 (2016). PubMed: 27824055
  • Martín-Maestro P  et al. PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease. Hum Mol Genet 25:792-806 (2016). PubMed: 26721933
  • Liu J  et al. Downregulation of let-7b promotes COL1A1 and COL1A2 expression in dermis and skin fibroblasts during heat wound repair. Mol Med Rep 13:2683-8 (2016). PubMed: 26861712
  • Marshall AD  et al. LAT1 is a putative therapeutic target in endometrioid endometrial carcinoma. Int J Cancer 139:2529-39 (2016). PubMed: 27486861
  • Rodina A  et al. The epichaperome is an integrated chaperome network that facilitates tumour survival. Nature 538:397-401 (2016). PubMed: 27706135
  • Li J  et al. The Long Non-Coding RNA LncRNA8975-1 is Upregulated in Hypertrophic Scar Fibroblasts and Controls Collagen Expression. Cell Physiol Biochem 40:326-334 (2016). PubMed: 27866191
  • Suarez SL  et al. Degradable acetalated dextran microparticles for tunable release of an engineered hepatocyte growth factor fragment. ACS Biomater Sci Eng 2:197-204 (2016). PubMed: 29333489
  • Zhu J  et al. Advanced glycosylation end product promotes forkhead box O1 and inhibits Wnt pathway to suppress capacities of epidermal stem cells. Am J Transl Res 8:5569-5579 (2016). PubMed: 28078027
  • Van Nostrand EL  et al. Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP). Nat Methods 13:508-14 (2016). PubMed: 27018577
  • Xu S  et al. ANRIL lncRNA triggers efficient therapeutic efficacy by reprogramming the aberrant INK4-hub in melanoma. Cancer Lett N/A:N/A (2016). WB ; Human . PubMed: 27461581
  • Fukumoto I  et al. MicroRNA expression signature of oral squamous cell carcinoma: functional role of microRNA-26a/b in the modulation of novel cancer pathways. Br J Cancer 112:891-900 (2015). PubMed: 25668004
  • Nishikawa R  et al. Tumour-suppressive microRNA-29s directly regulate LOXL2 expression and inhibit cancer cell migration and invasion in renal cell carcinoma. FEBS Lett 589:2136-45 (2015). PubMed: 26096783
  • Goto Y  et al. MicroRNA expression signature of castration-resistant prostate cancer: the microRNA-221/222 cluster functions as a tumour suppressor and disease progression marker. Br J Cancer 113:1055-65 (2015). PubMed: 26325107
  • Nishikawa R  et al. MicroRNA-205 inhibits cancer cell migration and invasion via modulation of centromere protein F regulating pathways in prostate cancer. Int J Urol 22:867-77 (2015). PubMed: 26059417
  • Lai C  et al. MicroRNA-133a inhibits proliferation and invasion, and induces apoptosis in gastric carcinoma cells via targeting fascin actin-bundling protein 1. Mol Med Rep 12:1473-8 (2015). PubMed: 25815687
  • Deng G  et al. MicroRNA-101 inhibits the migration and invasion of intrahepatic cholangiocarcinoma cells via direct suppression of vascular endothelial growth factor-C. Mol Med Rep 12:7079-85 (2015). PubMed: 26299768
  • Fraccarollo D  et al. Pentaerythritol Tetranitrate Targeting Myocardial Reactive Oxygen Species Production Improves Left Ventricular Remodeling and Function in Rats With Ischemic Heart Failure. Hypertension 66:978-87 (2015). PubMed: 26351025
  • Cai H  et al. Roundabout4 suppresses glioma-induced endothelial cell proliferation, migration and tube formation in vitro by inhibiting VEGR2-mediated PI3K/AKT and FAK signaling pathways. Cell Physiol Biochem 35:1689-705 (2015). PubMed: 25833462
  • Zhao S  et al. MicroRNA-148a inhibits the proliferation and promotes the paclitaxel-induced apoptosis of ovarian cancer cells by targeting PDIA3. Mol Med Rep 12:3923-3929 (2015). PubMed: 26004124
  • Kato M  et al. MicroRNA-26a/b directly regulate La-related protein 1 and inhibit cancer cell invasion in prostate cancer. Int J Oncol 47:710-8 (2015). PubMed: 26063484
  • Fu J  et al. Regulation of HIF-1 alpha by the proprotein convertases furin and PC7 in human squamous carcinoma cells. Mol Carcinog 54:698-706 (2015). PubMed: 24436242
  • Kang H  et al. Fluid shear stress promotes proprotein convertase-dependent activation of MT1-MMP. Biochem Biophys Res Commun 460:596-602 (2015). PubMed: 25800869
  • Wen Z  et al. MicroRNA-148a inhibits migration and invasion of ovarian cancer cells via targeting sphingosine-1-phosphate receptor 1. Mol Med Rep 12:3775-3780 (2015). PubMed: 26004261
  • Lazarev VF  et al. GAPDH binders as potential drugs for the therapy of polyglutamine diseases: design of a new screening assay. FEBS Lett 589:581-7 (2015). WB . PubMed: 25625921
  • Sharaf H  et al. Advanced glycation endproducts increase proliferation, migration and invasion of the breast cancer cell line MDA-MB-231. Biochim Biophys Acta 1852:429-41 (2015). PubMed: 25514746
  • Gao X  et al. Insufficient glucose supply is linked to hypothermia upon cold exposure in high-fat diet-fed mice lacking PEMT. J Lipid Res 56:1701-10 (2015). PubMed: 26113536
  • Taylor-Weiner H  et al. Traction forces mediated by integrin signaling are necessary for definitive endoderm specification. J Cell Sci 128:1961-8 (2015). PubMed: 25908864
  • Tatsumoto N  et al. Spironolactone ameliorates arterial medial calcification in uremic rats: the role of mineralocorticoid receptor signaling in vascular calcification. Am J Physiol Renal Physiol 309:F967-79 (2015). PubMed: 26336165
  • Hein K  et al. Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response. Sci Signal 8:ra30 (2015). PubMed: 25805888
  • Song M  et al. Interdependence of Parkin-Mediated Mitophagy and Mitochondrial Fission in Adult Mouse Hearts. Circ Res 117:346-51 (2015). PubMed: 26038571
  • Jiang L  et al. A novel role of microglial NADPH oxidase in mediating extra-synaptic function of norepinephrine in regulating brain immune homeostasis. Glia 63:1057-72 (2015). PubMed: 25740080
  • Gong X  et al. Bu Shen Huo Xue decoction restores endometrial leukemia-inhibitory factor but not Angiopoietin-2 expression, and improves uterine receptivity in the controlled ovarian stimulation rat model. Exp Ther Med 9:751-757 (2015). WB . PubMed: 25667623
  • Yang J  et al. Inhibition of G9a Histone Methyltransferase Converts Bone Marrow Mesenchymal Stem Cells to Cardiac Competent Progenitors. Stem Cells Int 2015:270428 (2015). WB . PubMed: 26089912
  • Wen G  et al. A Novel Role of Matrix Metalloproteinase-8 in Macrophage Differentiation and Polarization. J Biol Chem 290:19158-72 (2015). PubMed: 26092731
  • Gripp KW  et al. An attenuated phenotype of Costello syndrome in three unrelated individuals with a HRAS c.179G>A (p.Gly60Asp) mutation correlates with uncommon functional consequences. Am J Med Genet A 167A:2085-97 (2015). PubMed: 25914166
  • Cao J  et al. A universal strategy for regulating mRNA translation in prokaryotic and eukaryotic cells. Nucleic Acids Res 43:4353-62 (2015). PubMed: 25845589
  • Fey D  et al. Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients. Sci Signal 8:ra130 (2015). PubMed: 26696630
  • Madsen CT  et al. Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p. Nat Commun 6:7726 (2015). WB . PubMed: 26158509
  • Bianchini JM  et al. Reevaluating aE-catenin monomer and homodimer functions by characterizing E-cadherin/aE-catenin chimeras. J Cell Biol 210:1065-74 (2015). PubMed: 26416960
  • Cai H  et al. Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, Occludin, and Claudin-5 expression. J Neuropathol Exp Neurol 74:25-37 (2015). PubMed: 25470344
  • Gao X  et al. Lack of phosphatidylethanolamine N-methyltransferase alters hepatic phospholipid composition and induces endoplasmic reticulum stress. Biochim Biophys Acta 1852:2689-99 (2015). PubMed: 26391255
  • Karim AS  et al. Nox2 is a mediator of ischemia reperfusion injury. Am J Transplant 15:2888-99 (2015). PubMed: 26104383
  • Nichols CE  et al. Cardiac and mitochondrial dysfunction following acute pulmonary exposure to mountaintop removal mining particulate matter. Am J Physiol Heart Circ Physiol 309:H2017-30 (2015). PubMed: 26497962
  • Gray JM  et al. Corticotropin-releasing hormone drives anandamide hydrolysis in the amygdala to promote anxiety. J Neurosci 35:3879-92 (2015). PubMed: 25740517
  • Bergstrøm B  et al. TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-ß Production via a TAK1-IKKß-IRF5 Signaling Pathway. J Immunol 195:1100-11 (2015). WB ; Human . PubMed: 26085680
  • Quintens R  et al. Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development. Biol Open 4:331-44 (2015). WB . PubMed: 25681390
  • Zhang Y  et al. MicroRNA-145 inhibits migration and invasion via inhibition of fascin 1 protein expression in non-small-cell lung cancer cells. Mol Med Rep 12:6193-8 (2015). PubMed: 26238532
  • Jagannathan R  et al. Translational Regulation of the Mitochondrial Genome Following Redistribution of Mitochondrial MicroRNA in the Diabetic Heart. Circ Cardiovasc Genet 8:785-802 (2015). PubMed: 26377859
  • Botto S  et al. Kaposi Sarcoma Herpesvirus Induces HO-1 during De Novo Infection of Endothelial Cells via Viral miRNA-Dependent and -Independent Mechanisms. MBio 6:e00668 (2015). PubMed: 26045540
  • Wang L  et al. Biliary tract external drainage protects against intestinal barrier injury in hemorrhagic shock rats. World J Gastroenterol 21:12800-13 (2015). PubMed: 26668504
  • Calamaras TD  et al. The lipid peroxidation product 4-hydroxy-trans-2-nonenal causes protein synthesis in cardiac myocytes via activated mTORC1-p70S6K-RPS6 signaling. Free Radic Biol Med 82:137-46 (2015). PubMed: 25617592
  • Zhong W  et al. Cardioprotective effect of epigallocatechin-3-gallate against myocardial infarction in hypercholesterolemic rats. Exp Ther Med 9:405-410 (2015). PubMed: 25574206
  • Kett LR  et al. a-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2. J Neurosci 35:5724-42 (2015). PubMed: 25855184
  • Zheng K  et al. MicroRNA-133a suppresses colorectal cancer cell invasion by targeting Fascin1. Oncol Lett 9:869-874 (2015). WB . PubMed: 25621061
  • Sachweh MC  et al. Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells. Oncotarget 6:16488-506 (2015). WB . PubMed: 26029997
  • Hahn YK  et al. Chronic HIV-1 Tat and HIV reduce Rbfox3/NeuN: evidence for sex-related effects. Curr HIV Res 13:10-20 (2015). PubMed: 25760045
  • Zheng KL  et al. Alternative splicing of NUMB, APP and VEGFA as the features of pancreatic ductal carcinoma. Int J Clin Exp Pathol 8:6181-91 (2015). PubMed: 26261495
  • Lukas J  et al. Enzyme enhancers for the treatment of Fabry and Pompe disease. Mol Ther 23:456-64 (2015). PubMed: 25409744
  • Hao Q  et al. Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism. Am J Physiol Endocrinol Metab 308:E380-92 (2015). PubMed: 25516548
  • Mauro-Lizcano M  et al. New method to assess mitophagy flux by flow cytometry. Autophagy 11:833-43 (2015). PubMed: 25945953
  • Cai H  et al. The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144. Oncotarget 6:19759-79 (2015). IP . PubMed: 26078353
  • Rudisch A  et al. High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NF?B Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts. PLoS One 10:e0124283 (2015). WB . PubMed: 25919140
  • Huebbers CU  et al. High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma. Oncotarget 6:36172-84 (2015). PubMed: 26452026
  • Kramer D  et al. A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity. Cell Death Dis 6:e1634 (2015). PubMed: 25675294
  • Hieke N  et al. Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells. Autophagy 11:1471-83 (2015). PubMed: 26213203
  • Gratia M  et al. Rotavirus NSP3 Is a Translational Surrogate of the Poly(A) Binding Protein-Poly(A) Complex. J Virol 89:8773-82 (2015). PubMed: 26063427
  • Pasquier E  et al. ?-Actin plays a key role in endothelial cell motility and neovessel maintenance. Vasc Cell 7:2 (2015). WB ; Human . PubMed: 25705373
  • Kottmann RM  et al. Pharmacologic inhibition of lactate production prevents myofibroblast differentiation. Am J Physiol Lung Cell Mol Physiol 309:L1305-12 (2015). WB . PubMed: 26408551
  • Wang J  et al. Qishenyiqi Dropping Pill attenuates myocardial fibrosis in rats by inhibiting RAAS-mediated arachidonic acid inflammation. J Ethnopharmacol 176:375-84 (2015). WB ; Rat . PubMed: 26590099
  • Luxenburg C  et al. Wdr1-mediated cell shape dynamics and cortical tension are essential for epidermal planar cell polarity. Nat Cell Biol 17:592-604 (2015). Mouse . PubMed: 25915128
  • Baquero-Pérez B & Whitehouse A Hsp70 Isoforms Are Essential for the Formation of Kaposi's Sarcoma-Associated Herpesvirus Replication and Transcription Compartments. PLoS Pathog 11:e1005274 (2015). WB . PubMed: 26587836
  • Roda D  et al. EGF-Induced Acetylation of Heterogeneous Nuclear Ribonucleoproteins Is Dependent on KRAS Mutational Status in Colorectal Cancer Cells. PLoS One 10:e0130543 (2015). Human . PubMed: 26110767
  • Bai M  et al. OCT4 pseudogene 5 upregulates OCT4 expression to promote proliferation by competing with miR-145 in endometrial carcinoma. Oncol Rep 33:1745-52 (2015). PubMed: 25634023
  • Dhar G  et al. Acid gradient across plasma membrane can drive phosphate bond synthesis in cancer cells: acidic tumor milieu as a potential energy source. PLoS One 10:e0124070 (2015). WB . PubMed: 25874623
  • Tanios F  et al. CXCR4: A Potential Marker for Inflammatory Activity in Abdominal Aortic Aneurysm Wall. Eur J Vasc Endovasc Surg 50:745-53 (2015). WB ; Human . PubMed: 26346005
  • Klaver EJ  et al. Schistosoma mansoni Soluble Egg Antigens Induce Expression of the Negative Regulators SOCS1 and SHP1 in Human Dendritic Cells via Interaction with the Mannose Receptor. PLoS One 10:e0124089 (2015). WB ; Human . PubMed: 25897665
  • Kaczocha M  et al. Fatty acid binding protein deletion suppresses inflammatory pain through endocannabinoid/N-acylethanolamine-dependent mechanisms. Mol Pain 11:52 (2015). WB ; Mouse . PubMed: 26311517
  • Ye L  et al. Decreased Yes-Associated Protein-1 (YAP1) Expression in Pediatric Hearts with Ventricular Septal Defects. PLoS One 10:e0139712 (2015). PubMed: 26426694
  • Liu B  et al. Circulating microRNA-196a as a candidate diagnostic biomarker for chronic hepatitis C. Mol Med Rep 12:105-10 (2015). WB ; Human . PubMed: 25738504
  • Wang J  et al. Mechanism of QSYQ on anti-apoptosis mediated by different subtypes of cyclooxygenase in AMI induced heart failure rats. BMC Complement Altern Med 15:352 (2015). WB ; Rat . PubMed: 26445960
  • Gurt I  et al. The Sirt1 Activators SRT2183 and SRT3025 Inhibit RANKL-Induced Osteoclastogenesis in Bone Marrow-Derived Macrophages and Down-Regulate Sirt3 in Sirt1 Null Cells. PLoS One 10:e0134391 (2015). PubMed: 26226624
  • Yamagishi S  et al. Netrin-5 is highly expressed in neurogenic regions of the adult brain. Front Cell Neurosci 9:146 (2015). WB, ICC/IF ; Rat . PubMed: 25941474
  • Neumann E  et al. Expression changes of microRNA-1 and its targets Connexin 43 and brain-derived neurotrophic factor in the peripheral nervous system of chronic neuropathic rats. Mol Pain 11:39 (2015). WB ; Rat . PubMed: 26111928
  • Wakuda T  et al. Perinatal asphyxia alters neuregulin-1 and COMT gene expression in the medial prefrontal cortex in rats. Prog Neuropsychopharmacol Biol Psychiatry 56:149-54 (2015). PubMed: 25194460
  • Durk MR  et al. Vitamin D receptor activation induces P-glycoprotein and increases brain efflux of quinidine: an intracerebral microdialysis study in conscious rats. Pharm Res 32:1128-40 (2015). PubMed: 25319098
  • Blair BG  et al. A phosphoproteomic screen demonstrates differential dependence on HER3 for MAP kinase pathway activation by distinct PIK3CA mutations. Proteomics 15:318-26 (2015). WB ; Human . PubMed: 25367220
  • Lundby A  et al. Surface-expressed insulin receptors as well as IGF-I receptors both contribute to the mitogenic effects of human insulin and its analogues. J Appl Toxicol 35:842-50 (2015). PubMed: 25413577
  • Komarova EY  et al. The discovery of Hsp70 domain with cell-penetrating activity. Cell Stress Chaperones 20:343-54 (2015). PubMed: 25387797
  • Fan C  et al. Zbed3 contributes to malignant phenotype of lung cancer via regulating ß-catenin and P120-catenin 1. Mol Carcinog 54 Suppl 1:E138-47 (2015). PubMed: 25263389
  • Thapa D  et al. Transgenic overexpression of mitofilin attenuates diabetes mellitus-associated cardiac and mitochondria dysfunction. J Mol Cell Cardiol 79:212-23 (2015). PubMed: 25463274
  • Conwell SE  et al. Identification of TRIM27 as a novel degradation target of herpes simplex virus 1 ICP0. J Virol 89:220-9 (2015). WB . PubMed: 25320289
  • Munday DC  et al. Interactome analysis of the human respiratory syncytial virus RNA polymerase complex identifies protein chaperones as important cofactors that promote L-protein stability and RNA synthesis. J Virol 89:917-30 (2015). WB ; Human . PubMed: 25355874
  • Kahn OI  et al. Effects of kinesin-5 inhibition on dendritic architecture and microtubule organization. Mol Biol Cell 26:66-77 (2015). PubMed: 25355946
  • Myklebust LM  et al. Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects. Hum Mol Genet 24:1956-76 (2015). PubMed: 25489052
  • Hannan FM  et al. Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 (FHH3) demonstrate genotype-phenotype correlations, codon bias and dominant-negative effects. Hum Mol Genet 24:5079-92 (2015). PubMed: 26082470
  • Sirrs S  et al. Defects in fatty acid amide hydrolase 2 in a male with neurologic and psychiatric symptoms. Orphanet J Rare Dis 10:38 (2015). WB . PubMed: 25885783
  • Martínez A  et al. Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches. PLoS One 10:e0123352 (2015). WB ; Human . PubMed: 25923732
  • Oh HS  et al. Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters. MBio 6:e00345-15 (2015). WB ; Human . PubMed: 26015494
  • Schisler JC  et al. Cardiac energy dependence on glucose increases metabolites related to glutathione and activates metabolic genes controlled by mechanistic target of rapamycin. J Am Heart Assoc 4:N/A (2015). WB ; Mouse . PubMed: 25713290
  • Hollis F  et al. Mitochondrial function in the brain links anxiety with social subordination. Proc Natl Acad Sci U S A 112:15486-91 (2015). WB ; Rat . PubMed: 26621716
  • Tylden GD  et al. Brincidofovir (CMX001) inhibits BK polyomavirus replication in primary human urothelial cells. Antimicrob Agents Chemother 59:3306-16 (2015). WB ; Human . PubMed: 25801568
  • Henstridge CM  et al. Erratum to: Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse. Acta Neuropathol Commun 3:83 (2015). WB ; Human . PubMed: 26651483
  • Kosinsky RL  et al. Usp22 deficiency impairs intestinal epithelial lineage specification in vivo. Oncotarget 6:37906-18 (2015). WB . PubMed: 26431380
  • Song M  et al. Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts. Cell Metab 21:273-85 (2015). PubMed: 25600785
  • Song M  et al. Combined cardiomyocyte PKCd and PKCe gene deletion uncovers their central role in restraining developmental and reactive heart growth. Sci Signal 8:ra39 (2015). PubMed: 25900833
  • Slaats GG  et al. DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome. J Clin Invest 125:3657-66 (2015). PubMed: 26301811
  • Moreau K  et al. Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy. Nat Commun 6:8045 (2015). WB ; Human . PubMed: 26289944
  • Korb E  et al. BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice. Nat Neurosci 18:1464-73 (2015). WB ; Mouse . PubMed: 26301327
  • Liu F  et al. The effects of Livin shRNA on the response to cisplatin in HepG2 cells. Oncol Lett 10:2957-2961 (2015). PubMed: 26722271
  • Singh M  et al. STAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation. Oncotarget 6:27461-77 (2015). WB . PubMed: 26314961
  • Vincent G  et al. Changes in mitochondrial function and mitochondria associated protein expression in response to 2-weeks of high intensity interval training. Front Physiol 6:51 (2015). WB . PubMed: 25759671
  • Masvekar RR  et al. GSK3ß-activation is a point of convergence for HIV-1 and opiate-mediated interactive neurotoxicity. Mol Cell Neurosci 65:11-20 (2015). PubMed: 25616162
  • Holien T  et al. MYC amplifications in myeloma cell lines: correlation with MYC-inhibitor efficacy. Oncotarget 6:22698-705 (2015). WB . PubMed: 26087190
  • Schiffer M  et al. Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. Nat Med 21:601-9 (2015). WB . PubMed: 25962121
  • Galicia-Vázquez G  et al. eIF4AII is dispensable for miRNA-mediated gene silencing. RNA 21:1826-33 (2015). PubMed: 26286746
  • Kortüm F  et al. aPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor. PLoS One 10:e0132737 (2015). WB . PubMed: 26177020
  • Zhang J  et al. Critical role of the SPAK protein kinase CCT domain in controlling blood pressure. Hum Mol Genet 24:4545-58 (2015). PubMed: 25994507
  • Man KN  et al. Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis. Elife 4:N/A (2015). WB . PubMed: 26575293
  • Villares R  et al. Dido mutations trigger perinatal death and generate brain abnormalities and behavioral alterations in surviving adult mice. Proc Natl Acad Sci U S A 112:4803-8 (2015). PubMed: 25825751
  • Braun N  et al. UCP-3 uncoupling protein confers hypoxia resistance to renal epithelial cells and is upregulated in renal cell carcinoma. Sci Rep 5:13450 (2015). WB . PubMed: 26304588
  • Tang EI  et al. EB1 regulates tubulin and actin cytoskeletal networks at the sertoli cell blood-testis barrier in male rats: an in vitro study. Endocrinology 156:680-93 (2015). PubMed: 25456071
  • Rhéaume C  et al. A Highly Specific Monoclonal Antibody for Botulinum Neurotoxin Type A-Cleaved SNAP25. Toxins (Basel) 7:2354-70 (2015). PubMed: 26114335
  • Tomita T  et al. Sirt1-deficiency causes defective protein quality control. Sci Rep 5:12613 (2015). PubMed: 26219988
  • Drießen S  et al. Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy. Autophagy 11:1458-70 (2015). PubMed: 26207339
  • Adam MG  et al. SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status. Cell Cycle 14:3734-47 (2015). WB . PubMed: 26654769
  • Olsen OE  et al. Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B. Cell Commun Signal 13:27 (2015). WB . PubMed: 26047946
  • Du J  et al. Apoptin-modified human mesenchymal stem cells inhibit growth of lung carcinoma in nude mice. Mol Med Rep 12:1023-9 (2015). WB . PubMed: 25816208
  • Manz BN  et al. Small molecule inhibition of Csk alters affinity recognition by T cells. Elife 4:N/A (2015). PubMed: 26302204
  • Carter WG  et al. Isoaspartate, carbamoyl phosphate synthase-1, and carbonic anhydrase-III as biomarkers of liver injury. Biochem Biophys Res Commun 458:626-31 (2015). PubMed: 25684186
  • Ruelas DS  et al. MicroRNA-155 Reinforces HIV Latency. J Biol Chem 290:13736-48 (2015). PubMed: 25873391
  • Deml B  et al. Mutations in MAB21L2 result in ocular Coloboma, microcornea and cataracts. PLoS Genet 11:e1005002 (2015). PubMed: 25719200
  • Kurgonaite K  et al. Essential role of endocytosis for interleukin-4-receptor-mediated JAK/STAT signalling. J Cell Sci 128:3781-95 (2015). PubMed: 26306492
  • Ma Y  et al. Inhibiting tumor necrosis factor-a signaling attenuates postoperative cognitive dysfunction in aged rats. Mol Med Rep 12:3095-100 (2015). PubMed: 25955232
  • Kumar R  et al. MEI4 – a central player in the regulation of meiotic DNA double-strand break formation in the mouse. J Cell Sci 128:1800-11 (2015). PubMed: 25795304
  • Wang X  et al. LEF-1 Regulates Tyrosinase Gene Transcription In Vitro. PLoS One 10:e0143142 (2015). WB . PubMed: 26580798
  • Magli A  et al. Pax3 and Tbx5 specify whether PDGFRa+ cells assume skeletal or cardiac muscle fate in differentiating embryonic stem cells. Stem Cells 32:2072-83 (2014). PubMed: 24677751
  • Nishikawa R  et al. Tumor-suppressive microRNA-218 inhibits cancer cell migration and invasion via targeting of LASP1 in prostate cancer. Cancer Sci 105:802-11 (2014). WB . PubMed: 24815849
  • Zatti S  et al. Complete restoration of multiple dystrophin isoforms in genetically corrected Duchenne muscular dystrophy patient-derived cardiomyocytes. Mol Ther Methods Clin Dev 1:1 (2014). WB . PubMed: 26015941
  • Cheng TL  et al. MeCP2 suppresses nuclear microRNA processing and dendritic growth by regulating the DGCR8/Drosha complex. Dev Cell 28:547-60 (2014). PubMed: 24636259
  • Kikkawa N  et al. microRNA-504 inhibits cancer cell proliferation via targeting CDK6 in hypopharyngeal squamous cell carcinoma. Int J Oncol 44:2085-92 (2014). PubMed: 24647829
  • Xu H  et al. Tumor-associated macrophage-derived IL-6 and IL-8 enhance invasive activity of LoVo cells induced by PRL-3 in a KCNN4 channel-dependent manner. BMC Cancer 14:330 (2014). PubMed: 24885636
  • Huang G  et al. Characterization of transfusion-elicited acute antibody-mediated rejection in a rat model of kidney transplantation. Am J Transplant 14:1061-72 (2014). PubMed: 24708533
  • Karnavas T  et al. Histone content increases in differentiating embryonic stem cells. Front Physiol 5:330 (2014). WB . PubMed: 25221520
  • Parenti I  et al. Overall and allele-specific expression of the SMC1A gene in female Cornelia de Lange syndrome patients and healthy controls. Epigenetics 9: (2014). PubMed: 24756084
  • Sverdlov AL  et al. High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II. J Mol Cell Cardiol N/A:N/A (2014). WB ; Mouse . PubMed: 25109264
  • Qiu Q  et al. Time-Course of the Effects of QSYQ in Promoting Heart Function in Ameroid Constrictor-Induced Myocardial Ischemia Pigs. Evid Based Complement Alternat Med 2014:571076 (2014). WB ; Pig . PubMed: 24817898
  • Liu R  et al. Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking. Autophagy 10:1241-55 (2014). PubMed: 24905460
  • Bejarano E  et al. Connexins modulate autophagosome biogenesis. Nat Cell Biol 16:401-14 (2014). PubMed: 24705551
  • Aries A  et al. Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate. Cell Death Dis 5:e1566 (2014). WB ; Rat . PubMed: 25501827
  • Sakellariou GK  et al. Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice. FASEB J 28:1666-81 (2014). WB ; Mouse . PubMed: 24378874
  • Cobley JN  et al. Lifelong training preserves some redox-regulated adaptive responses after an acute exercise stimulus in aged human skeletal muscle. Free Radic Biol Med 70:23-32 (2014). WB ; Human . PubMed: 24525000
  • Reed SM  et al. NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas. PLoS One 9:e112126 (2014). WB ; Mouse . PubMed: 25393878
  • Landon AL  et al. MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL. Nat Commun 5:5413 (2014). WB . PubMed: 25403230
  • Hegedus A  et al. HIV-1 pathogenicity and virion production are dependent on the metabolic phenotype of activated CD4+ T cells. Retrovirology 11:98 (2014). WB . PubMed: 25421745
  • Reeves E  et al. Functionally distinct ERAP1 allotype combinations distinguish individuals with Ankylosing Spondylitis. Proc Natl Acad Sci U S A 111:17594-9 (2014). WB . PubMed: 25422414
  • Mohseni M  et al. MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers. Proc Natl Acad Sci U S A 111:17606-11 (2014). WB ; Human . PubMed: 25422431
  • Neumayer G & Nguyen MD TPX2 impacts acetylation of histone H4 at lysine 16: implications for DNA damage response. PLoS One 9:e110994 (2014). WB ; Human . PubMed: 25365214
  • Volk N  et al. MicroRNA-19b associates with Ago2 in the amygdala following chronic stress and regulates the adrenergic receptor beta 1. J Neurosci 34:15070-82 (2014). PubMed: 25378171
  • Ravel-Chapuis A  et al. The RNA-binding protein Staufen1 impairs myogenic differentiation via a c-myc-dependent mechanism. Mol Biol Cell 25:3765-78 (2014). WB ; Mouse . PubMed: 25208565
  • Hagen J  et al. RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner. Cancer Res 74:6661-70 (2014). PubMed: 25273089
  • Wu MV  et al. Thermogenic capacity is antagonistically regulated in classical brown and white subcutaneous fat depots by high fat diet and endurance training in rats: impact on whole-body energy expenditure. J Biol Chem 289:34129-40 (2014). PubMed: 25344623
  • Christianson JP  et al. Learned stressor resistance requires extracellular signal-regulated kinase in the prefrontal cortex. Front Behav Neurosci 8:348 (2014). WB ; Rat . PubMed: 25324750
  • Tanida I  et al. A super-ecliptic, pHluorin-mKate2, tandem fluorescent protein-tagged human LC3 for the monitoring of mammalian autophagy. PLoS One 9:e110600 (2014). PubMed: 25340751
  • Komatsu Y  et al. Oncogenic Ras inhibits IRF1 to promote viral oncolysis. Oncogene N/A:N/A (2014). PubMed: 25347735
  • Chen JT  et al. Presynaptic GABAergic inhibition regulated by BDNF contributes to neuropathic pain induction. Nat Commun 5:5331 (2014). WB ; Mouse . PubMed: 25354791
  • Ducroux A  et al. The Tudor domain protein Spindlin1 is involved in intrinsic antiviral defense against incoming hepatitis B Virus and herpes simplex virus type 1. PLoS Pathog 10:e1004343 (2014). WB ; Human . PubMed: 25211330
  • Prasad R  et al. Thioredoxin Reductase 2 (TXNRD2) mutation associated with familial glucocorticoid deficiency (FGD). J Clin Endocrinol Metab 99:E1556-63 (2014). WB ; Human . PubMed: 24601690
  • Bentham MJ  et al. NS2 is dispensable for efficient assembly of hepatitis C virus-like particles in a bipartite trans-encapsidation system. J Gen Virol 95:2427-41 (2014). PubMed: 25024280
  • Goto Y  et al. The microRNA-23b/27b/24-1 cluster is a disease progression marker and tumor suppressor in prostate cancer. Oncotarget 5:7748-59 (2014). WB ; Human . PubMed: 25115396
  • Hantke J  et al. c-Jun activation in Schwann cells protects against loss of sensory axons in inherited neuropathy. Brain 137:2922-37 (2014). PubMed: 25216747
  • Lucas E  et al. Downregulation of G protein-coupled receptor kinase 2 levels enhances cardiac insulin sensitivity and switches on cardioprotective gene expression patterns. Biochim Biophys Acta 1842:2448-56 (2014). PubMed: 25239306
  • Maney NJ  et al. Dendritic cell maturation and survival are differentially regulated by TNFR1 and TNFR2. J Immunol 193:4914-23 (2014). PubMed: 25288570
  • Cheadle L & Biederer T Activity-dependent regulation of dendritic complexity by semaphorin 3A through Farp1. J Neurosci 34:7999-8009 (2014). IP . PubMed: 24899721
  • Vignarajan S  et al. Loss of PTEN stabilizes the lipid modifying enzyme cytosolic phospholipase A2a via AKT in prostate cancer cells. Oncotarget 5:6289-99 (2014). Human . PubMed: 25026288
  • Joly S  et al. New mouse retinal stroke model reveals direction-selective circuit damage linked to permanent optokinetic response loss. Invest Ophthalmol Vis Sci 55:4476-89 (2014). PubMed: 24970264
  • Toret CP  et al. A genome-wide screen identifies conserved protein hubs required for cadherin-mediated cell-cell adhesion. J Cell Biol 204:265-79 (2014). WB ; Dog . PubMed: 24446484
  • Zhao L  et al. Notch signaling regulates cardiomyocyte proliferation during zebrafish heart regeneration. Proc Natl Acad Sci U S A 111:1403-8 (2014). Zebrafish . PubMed: 24474765
  • Sharma BN  et al. Antiviral effects of artesunate on polyomavirus BK replication in primary human kidney cells. Antimicrob Agents Chemother 58:279-89 (2014). Human . PubMed: 24145549
  • Galicia-Vázquez G  et al. Regulation of eukaryotic initiation factor 4AII by MyoD during murine myogenic cell differentiation. PLoS One 9:e87237 (2014). WB ; Mouse . PubMed: 24466343
  • Gabandé-Rodríguez E  et al. High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A. Cell Death Differ N/A:N/A (2014). PubMed: 24488099
  • Zhu J  et al. The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor a and modulates estrogen-stimulated breast cancer cell proliferation. Oncogene N/A:N/A (2014). Human . PubMed: 24441041
  • Mostafa AA  et al. Activation of ERa signaling differentially modulates IFN-? induced HLA-class II expression in breast cancer cells. PLoS One 9:e87377 (2014). Human . PubMed: 24475282
  • Schulz R  et al. HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer. Cell Death Dis 5:e980 (2014). WB ; Mouse, Human . PubMed: 24384723
  • Kempf A  et al. The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. PLoS Biol 12:e1001763 (2014). WB . PubMed: 24453941
  • Born N  et al. The B-subdomain of the Xenopus laevis XFIN KRAB-AB domain is responsible for its weaker transcriptional repressor activity compared to human ZNF10/Kox1. PLoS One 9:e87609 (2014). WB . PubMed: 24498343
  • Wojewoda M  et al. Running performance at high running velocities is impaired but V'O(2max) and peripheral endothelial function are preserved in IL-6?/? mice. PLoS One 9:e88333 (2014). WB ; Mouse . PubMed: 24533077
  • Wang Y  et al. DanQi Pill protects against heart failure through the arachidonic acid metabolism pathway by attenuating different cyclooxygenases and leukotrienes B4. BMC Complement Altern Med 14:67 (2014). WB . PubMed: 24555740
  • Presman DM  et al. Live cell imaging unveils multiple domain requirements for in vivo dimerization of the glucocorticoid receptor. PLoS Biol 12:e1001813 (2014). WB ; Mouse . PubMed: 24642507
  • Tsang VW  et al. AAV-mediated overexpression of neuroserpin in the hippocampus decreases PSD-95 expression but does not affect hippocampal-dependent learning and memory. PLoS One 9:e91050 (2014). Human . PubMed: 24608243
  • Kapoor-Vazirani P & Vertino PM A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing. J Biol Chem 289:7425-37 (2014). WB . PubMed: 24459145
  • Thireau J  et al. ?-adrenergic blockade combined with subcutaneous B-type natriuretic peptide: a promising approach to reduce ventricular arrhythmia in heart failure? Heart 100:833-41 (2014). Mouse . PubMed: 24667281
  • Wen W  et al. VER-155008, a small molecule inhibitor of HSP70 with potent anti-cancer activity on lung cancer cell lines. Exp Biol Med (Maywood) 239:638-45 (2014). PubMed: 24676905
  • Tan FE & Elowitz MB Brf1 posttranscriptionally regulates pluripotency and differentiation responses downstream of Erk MAP kinase. Proc Natl Acad Sci U S A 111:E1740-8 (2014). PubMed: 24733888
  • O'Reilly S  et al. Interleukin-6 (IL-6) trans signaling drives a STAT3-dependent pathway that leads to hyperactive transforming growth factor-ß (TGF-ß) signaling promoting SMAD3 activation and fibrosis via Gremlin protein. J Biol Chem 289:9952-60 (2014). WB ; Human . PubMed: 24550394
  • Erdozain AM  et al. Alcohol-related brain damage in humans. PLoS One 9:e93586 (2014). WB ; Human . PubMed: 24699688
  • Zavodszky E  et al. Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy. Nat Commun 5:3828 (2014). WB ; Human . PubMed: 24819384
  • Roberge S  et al. TNF-a-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes. Cardiovasc Res 103:90-9 (2014). WB ; Mouse . PubMed: 24802330
  • Rappe U  et al. Nuclear ARVCF protein binds splicing factors and contributes to the regulation of alternative splicing. J Biol Chem 289:12421-34 (2014). Human . PubMed: 24644279
  • Uechi H  et al. Characterization of the testis-specific proteasome subunit a4s in mammals. J Biol Chem 289:12365-74 (2014). PubMed: 24668818
  • Lohoefer F  et al. Quantitative expression and localization of cysteine and aspartic proteases in human abdominal aortic aneurysms. Exp Mol Med 46:e95 (2014). WB ; Human . PubMed: 24833013
  • Durk MR  et al. 1a,25-Dihydroxyvitamin D3 reduces cerebral amyloid-ß accumulation and improves cognition in mouse models of Alzheimer's disease. J Neurosci 34:7091-101 (2014). Mouse . PubMed: 24849345
  • Yuan FN  et al. Vitamin D signaling regulates oral keratinocyte proliferation in vitro and in vivo. Int J Oncol 44:1625-33 (2014). WB . PubMed: 24626468
  • Chen CC  et al. NF-?B-mediated transcriptional upregulation of TNFAIP2 by the Epstein-Barr virus oncoprotein, LMP1, promotes cell motility in nasopharyngeal carcinoma. Oncogene 33:3648-59 (2014). WB ; Human . PubMed: 23975427
  • van der Wijst J  et al. Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction. Biochem J 460:165-75 (2014). Human . PubMed: 24650431
  • Zhang H  et al. Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1. Proc Natl Acad Sci U S A 111:E2261-70 (2014). Human . PubMed: 24843141
  • Fukumoto I  et al. Identification of tumour suppressive microRNA-451a in hypopharyngeal squamous cell carcinoma based on microRNA expression signature. Br J Cancer 111:386-94 (2014). WB . PubMed: 24918822
  • Menafra R  et al. Genome-Wide Binding of MBD2 Reveals Strong Preference for Highly Methylated Loci. PLoS One 9:e99603 (2014). WB ; Human . PubMed: 24927503
  • Masvekar RR  et al. Morphine Enhances HIV-1SF162-Mediated Neuron Death and Delays Recovery of Injured Neurites. PLoS One 9:e100196 (2014). WB ; Mouse . PubMed: 24949623
  • Li X  et al. A RG-II Type Polysaccharide Purified from Aconitum coreanum Alleviates Lipopolysaccharide-Induced Inflammation by Inhibiting the NF-?B Signal Pathway. PLoS One 9:e99697 (2014). PubMed: 24927178
  • Pulliero A  et al. Oxidative damage and autophagy in the human trabecular meshwork as related with ageing. PLoS One 9:e98106 (2014). WB ; Human . PubMed: 24945152
  • Bertaggia E  et al. Haptoglobin is required to prevent oxidative stress and muscle atrophy. PLoS One 9:e100745 (2014). WB ; Mouse . PubMed: 24959824
  • Peng Y & Zhang L Activation of the TLR1/2 pathway induces the shaping of the immune response status of peripheral blood leukocytes. Exp Ther Med 7:1708-1712 (2014). WB ; Human . PubMed: 24926371
  • Xiao X  et al. N-wasp is required for structural integrity of the blood-testis barrier. PLoS Genet 10:e1004447 (2014). WB ; Mouse . PubMed: 24967734
  • d'Adhemar CJ  et al. The MyD88+ Phenotype Is an Adverse Prognostic Factor in Epithelial Ovarian Cancer. PLoS One 9:e100816 (2014). WB ; Human . PubMed: 24977712
  • Hellewell AL  et al. Analysis of familial hemophagocytic lymphohistiocytosis type 4 (FHL-4) mutant proteins reveals that S-acylation is required for the function of syntaxin 11 in natural killer cells. PLoS One 9:e98900 (2014). Human . PubMed: 24910990
  • Altintas MM  et al. Reduction of Proteinuria through Podocyte Alkalinization. J Biol Chem 289:17454-17467 (2014). WB ; Mouse . PubMed: 24817115
  • Jo S  et al. GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease. Nat Med N/A:N/A (2014). PubMed: 24973918
  • Barmada SJ  et al. Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models. Nat Chem Biol 10:677-85 (2014). PubMed: 24974230
  • Han Z  et al. Small-molecule probes targeting the viral PPxY-host Nedd4 interface block egress of a broad range of RNA viruses. J Virol 88:7294-306 (2014). PubMed: 24741084
  • Aligny C  et al. Ketamine alters cortical integration of GABAergic interneurons and induces long-term sex-dependent impairments in transgenic Gad67-GFP mice. Cell Death Dis 5:e1311 (2014). WB ; Mouse . PubMed: 24991763
  • Banerjee S  et al. Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1ßMYPT1 phosphatase complex and the SCFßTrCP E3 ubiquitin ligase. Biochem J 461:233-45 (2014). WB . PubMed: 24785407
  • Zeman MK  et al. DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis. J Cell Biol 206:183-97 (2014). Human . PubMed: 25023518
  • Meli L  et al. Three dimensional cellular microarray platform for human neural stem cell differentiation and toxicology. Stem Cell Res 13:36-47 (2014). WB ; Human . PubMed: 24816401
  • Shin JH  et al. Ischemic brain extract increases SDF-1 expression in astrocytes through the CXCR2/miR-223/miR-27b pathway. Biochim Biophys Acta 1839:826-36 (2014). PubMed: 24999035
  • Eales KL  et al. The MK2/3 cascade regulates AMPAR trafficking and cognitive flexibility. Nat Commun 5:4701 (2014). WB ; Mouse . PubMed: 25134715
  • Rothan HA  et al. Three-dimensional culture environment increases the efficacy of platelet rich plasma releasate in prompting skin fibroblast differentiation and extracellular matrix formation. Int J Med Sci 11:1029-38 (2014). WB ; Human . PubMed: 25136258
  • Patel K  et al. The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver. Nat Commun 5:4535 (2014). WB . PubMed: 25088745
  • Ramratnam M  et al. Transgenic knockdown of cardiac sodium/glucose cotransporter 1 (SGLT1) attenuates PRKAG2 cardiomyopathy, whereas transgenic overexpression of cardiac SGLT1 causes pathologic hypertrophy and dysfunction in mice. J Am Heart Assoc 3:N/A (2014). PubMed: 25092788
  • Freeman MC  et al. Coronaviruses induce entry-independent, continuous macropinocytosis. MBio 5:e01340-14 (2014). Mouse . PubMed: 25096879
  • Entin-Meer M  et al. The transient receptor potential vanilloid 2 cation channel is abundant in macrophages accumulating at the peri-infarct zone and may enhance their migration capacity towards injured cardiomyocytes following myocardial infarction. PLoS One 9:e105055 (2014). WB ; Rat . PubMed: 25136832
  • Wang ZY  et al. Activation of CB1 inhibits NGF-induced sensitization of TRPV1 in adult mouse afferent neurons. Neuroscience 277:679-89 (2014). WB ; Mouse . PubMed: 25088915
  • Tan Y  et al. Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression. Nat Commun 5:4619 (2014). WB ; Mouse . PubMed: 25099074
  • Seeher S  et al. Secisbp2 is essential for embryonic development and enhances selenoprotein expression. Antioxid Redox Signal 21:835-49 (2014). WB ; Mouse . PubMed: 24274065
  • Li C  et al. Qishenyiqi protects ligation-induced left ventricular remodeling by attenuating inflammation and fibrosis via STAT3 and NF-?B signaling pathway. PLoS One 9:e104255 (2014). WB ; Rat . PubMed: 25122164
  • Fan C  et al. Btbd7 contributes to reduced E-cadherin expression and predicts poor prognosis in non-small cell lung cancer. BMC Cancer 14:704 (2014). WB ; Human . PubMed: 25253020
  • Sieren JC  et al. Development and translational imaging of a TP53 porcine tumorigenesis model. J Clin Invest 124:4052-66 (2014). WB ; Pig . PubMed: 25105366
  • Chucair-Elliott AJ  et al. Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells. Glia 62:1418-34 (2014). PubMed: 24807365
  • Wang Q  et al. Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase. J Neurosci 34:12490-503 (2014). PubMed: 25209287
  • Hsieh YL  et al. Remote dose-dependent effects of dry needling at distant myofascial trigger spots of rabbit skeletal muscles on reduction of substance p levels of proximal muscle and spinal cords. Biomed Res Int 2014:982121 (2014). PubMed: 25276839
  • Landmann H  et al. UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib. Cell Death Dis 5:e1411 (2014). WB ; Human . PubMed: 25210794
  • Zhang Y  et al. Combined therapy with COX-2 inhibitor and 20-HETE inhibitor reduces colon tumor growth and the adverse effects of ischemic stroke associated with COX-2 inhibition. Am J Physiol Regul Integr Comp Physiol 307:R693-703 (2014). WB ; Mouse . PubMed: 24990856
  • Wang Y  et al. Sex-dependent, zinc-induced dephosphorylation of phospholamban by tissue-nonspecific alkaline phosphatase in the cardiac sarcomere. Am J Physiol Heart Circ Physiol 307:H933-8 (2014). PubMed: 25015959
  • Li XQ  et al. Sevoflurane preconditioning ameliorates neuronal deficits by inhibiting microglial MMP-9 expression after spinal cord ischemia/reperfusion in rats. Mol Brain 7:69 (2014). WB ; Rat . PubMed: 25186151
  • Moreau K  et al. PICALM modulates autophagy activity and tau accumulation. Nat Commun 5:4998 (2014). WB . PubMed: 25241929
  • Fiedler J  et al. Functional microRNA library screening identifies the hypoxamir miR-24 as a potent regulator of smooth muscle cell proliferation and vascularization. Antioxid Redox Signal 21:1167-76 (2014). WB ; Human . PubMed: 24063572
  • van der Kooij MA  et al. Role for MMP-9 in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioural alterations. Nat Commun 5:4995 (2014). WB ; Rat . PubMed: 25232752
  • Hsieh YL  et al. Fluence-dependent effects of low-level laser therapy in myofascial trigger spots on modulation of biochemicals associated with pain in a rabbit model. Lasers Med Sci N/A:N/A (2014). PubMed: 25190639
  • Kuzaj P  et al. Large-scaled metabolic profiling of human dermal fibroblasts derived from pseudoxanthoma elasticum patients and healthy controls. PLoS One 9:e108336 (2014). WB ; Human . PubMed: 25265166
  • Tamura Y  et al. Postexercise whole body heat stress additively enhances endurance training-induced mitochondrial adaptations in mouse skeletal muscle. Am J Physiol Regul Integr Comp Physiol 307:R931-43 (2014). PubMed: 25080501
  • Choo KB  et al. MicroRNA-5p and -3p co-expression and cross-targeting in colon cancer cells. J Biomed Sci 21:95 (2014). PubMed: 25287248
  • Laviolette LA  et al. 17ß-estradiol upregulates GREB1 and accelerates ovarian tumor progression in vivo. Int J Cancer 135:1072-84 (2014). WB ; Mouse . PubMed: 24469735
  • Wang W  et al. Amyloid precursor protein a- and ß-cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2. FASEB J 28:849-60 (2014). PubMed: 24249638
  • Nishikawa R  et al. Tumor-suppressive microRNA-29s inhibit cancer cell migration and invasion via targeting LAMC1 in prostate cancer. Int J Oncol 45:401-10 (2014). PubMed: 24820027
  • Li Y  et al. The study of fetal rat model of intra-amniotic isoproterenol injection induced heart dysfunction and phenotypic switch of contractile proteins. Biomed Res Int 2014:360687 (2014). WB . PubMed: 25136580
  • Vencken SF  et al. An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines. BMC Genomics 15:711 (2014). PubMed: 25156079
  • Screen M  et al. Abnormal splicing of NEDD4 in myotonic dystrophy type 2: possible link to statin adverse reactions. Am J Pathol 184:2322-32 (2014). PubMed: 24907641
  • Lo Verso F  et al. Autophagy is not required to sustain exercise and PRKAA1/AMPK activity but is important to prevent mitochondrial damage during physical activity. Autophagy 10:1883-94 (2014). PubMed: 25483961
  • Despa S  et al. Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model. J Am Heart Assoc 3:N/A (2014). PubMed: 25146704
  • Reed SM  et al. Nuclear interactor of ARF and Mdm2 regulates multiple pathways to activate p53. Cell Cycle 13:1288-98 (2014). WB . PubMed: 24621507
  • Avitzour M  et al. FMR1 epigenetic silencing commonly occurs in undifferentiated fragile X-affected embryonic stem cells. Stem Cell Reports 3:699-706 (2014). WB . PubMed: 25418717
  • Toret CP  et al. An Elmo-Dock complex locally controls Rho GTPases and actin remodeling during cadherin-mediated adhesion. J Cell Biol 207:577-87 (2014). PubMed: 25452388
  • Ptasinska A  et al. Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal. Cell Rep 8:1974-1988 (2014). WB . PubMed: 25242324
  • King IN  et al. The RNA-binding protein TDP-43 selectively disrupts microRNA-1/206 incorporation into the RNA-induced silencing complex. J Biol Chem 289:14263-71 (2014). WB ; Mouse . PubMed: 24719334
  • Hall ME  et al. Rescue of cardiac leptin receptors in db/db mice prevents myocardial triglyceride accumulation. Am J Physiol Endocrinol Metab 307:E316-25 (2014). WB . PubMed: 24939734
  • Henriksen S  et al. The human fetal glial cell line SVG p12 contains infectious BK polyomavirus. J Virol 88:7556-68 (2014). PubMed: 24760884
  • Helsby MA  et al. CiteAb: a searchable antibody database that ranks antibodies by the number of times they have been cited. BMC Cell Biol 15:6 (2014). PubMed: 24528853
  • Totonchy JE  et al. CXCR7 expression disrupts endothelial cell homeostasis and causes ligand-dependent invasion. Cell Adh Migr 8:165-76 (2014). PubMed: 24710021
  • Gentil BJ  et al. A two-hybrid screen identifies an unconventional role for the intermediate filament peripherin in regulating the subcellular distribution of the SNAP25-interacting protein, SIP30. J Neurochem 131:588-601 (2014). PubMed: 25113441
  • Durand M  et al. Monocytes from patients with osteoarthritis display increased osteoclastogenesis and bone resorption: the In Vitro Osteoclast Differentiation in Arthritis study. Arthritis Rheum 65:148-58 (2013). PubMed: 23044761
  • Satish L  et al. Increased CCT-eta expression is a marker of latent and active disease and a modulator of fibroblast contractility in Dupuytren's contracture. Cell Stress Chaperones 18:397-404 (2013). PubMed: 23292503
  • Magli A  et al. Functional dissection of Pax3 in paraxial mesoderm development and myogenesis. Stem Cells 31:59-70 (2013). PubMed: 23081715
  • Muniz VP  et al. RABL6A Promotes Oxaliplatin Resistance in Tumor Cells and Is a New Marker of Survival for Resected Pancreatic Ductal Adenocarcinoma Patients. Genes Cancer 4:273-84 (2013). PubMed: 24167655
  • Chow EC  et al. Temporal changes in tissue 1a,25-dihydroxyvitamin D3, vitamin D receptor target genes, and calcium and PTH levels after 1,25(OH)2D3 treatment in mice. Am J Physiol Endocrinol Metab 304:E977-89 (2013). PubMed: 23482451
  • Burchell VS  et al. The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy. Nat Neurosci 16:1257-65 (2013). PubMed: 23933751
  • Voss M  et al. Protein phosphatase 4 is phosphorylated and inactivated by Cdk in response to spindle toxins and interacts with ?-tubulin. Cell Cycle 12:2876-87 (2013). PubMed: 23966160
  • Hovakimyan M  et al. Olfactory deficits in Niemann-Pick type C1 (NPC1) disease. PLoS One 8:e82216 (2013). PubMed: 24391715
  • Wong EW  et al. Secreted Frizzled-related protein 1 (sFRP1) regulates spermatid adhesion in the testis via dephosphorylation of focal adhesion kinase and the nectin-3 adhesion protein complex. FASEB J 27:464-77 (2013). PubMed: 23073828
  • Elisia I & Kitts DD Modulation of NF-?B and Nrf2 control of inflammatory responses in FHs 74 Int cell line is tocopherol isoform-specific. Am J Physiol Gastrointest Liver Physiol 305:G940-9 (2013). PubMed: 24136788
  • Jung C  et al. RNA helicase Ddx5 and the noncoding RNA SRA act as coactivators in the Notch signaling pathway. Biochim Biophys Acta 1833:1180-9 (2013). PubMed: 23396200
  • Gong X  et al. Effects of "Bu Shen Huo Xue Decoction" on the Endometrial Morphology and Expression of Leukaemia Inhibitory Factor in the Rat Uterus during the Oestrous Cycle. Evid Based Complement Alternat Med 2013:496036 (2013). PubMed: 23710223
  • Wilzén A  et al. ERBB3 is a marker of a ganglioneuroblastoma/ganglioneuroma-like expression profile in neuroblastic tumours. Mol Cancer 12:70 (2013). WB . PubMed: 23835063
  • Ishida E  et al. Crosstalk between thyroid hormone receptor and liver X receptor in the regulation of selective Alzheimer's disease indicator-1 gene expression. PLoS One 8:e54901 (2013). WB . PubMed: 23359226
  • Volkmann I  et al. MicroRNA-mediated epigenetic silencing of sirtuin1 contributes to impaired angiogenic responses. Circ Res 113:997-1003 (2013). PubMed: 23960241
  • Ferreira JV  et al. STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy. Autophagy 9:1349-66 (2013). PubMed: 23880665
  • Xiao Q  et al. Functional role of matrix metalloproteinase-8 in stem/progenitor cell migration and their recruitment into atherosclerotic lesions. Circ Res 112:35-47 (2013). PubMed: 23071158
  • Alqudah MA  et al. NOTCH3 Is a Prognostic Factor That Promotes Glioma Cell Proliferation, Migration and Invasion via Activation of CCND1 and EGFR. PLoS One 8:e77299 (2013). WB ; Human . PubMed: 24143218
  • Chua JP  et al. Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy. Hum Mol Genet N/A:N/A (2013). PubMed: 24150846
  • Kinoshita T  et al. Tumour-suppressive microRNA-29s inhibit cancer cell migration and invasion by targeting laminin-integrin signalling in head and neck squamous cell carcinoma. Br J Cancer 109:2636-45 (2013). WB ; Human . PubMed: 24091622
  • Feng H  et al. Calumenin-15 facilitates filopodia formation by promoting TGF-ß superfamily cytokine GDF-15 transcription. Cell Death Dis 4:e870 (2013). PubMed: 24136234
  • Porter IM  et al. Bod1 regulates protein phosphatase 2A at mitotic kinetochores. Nat Commun 4:2677 (2013). WB ; Human . PubMed: 24157919
  • D'Aniello C  et al. The G-protein-coupled receptor APJ is expressed in the second heart field and regulates Cerberus-Baf60c axis in embryonic stem cell cardiomyogenesis. Cardiovasc Res 100:95-104 (2013). PubMed: 23787002
  • Bentham MJ  et al. Mutations in hepatitis C virus p7 reduce both the egress and infectivity of assembled particles via impaired proton channel function. J Gen Virol 94:2236-48 (2013). PubMed: 23907396
  • Oddoux S  et al. Microtubules that form the stationary lattice of muscle fibers are dynamic and nucleated at Golgi elements. J Cell Biol 203:205-13 (2013). PubMed: 24145165
  • Stavru F  et al. Atypical mitochondrial fission upon bacterial infection. Proc Natl Acad Sci U S A 110:16003-8 (2013). WB ; Human . PubMed: 24043775
  • Kojima S  et al. The tumor-suppressive microRNA-143/145 cluster inhibits cell migration and invasion by targeting GOLM1 in prostate cancer. J Hum Genet N/A:N/A (2013). PubMed: 24284362
  • Zhang X  et al. RABL6A, a Novel RAB-Like Protein, Controls Centrosome Amplification and Chromosome Instability in Primary Fibroblasts. PLoS One 8:e80228 (2013). Mouse . PubMed: 24282525
  • Martinez-Lopez N  et al. Autophagy proteins regulate ERK phosphorylation. Nat Commun 4:2799 (2013). Mouse . PubMed: 24240988
  • Chu BW  et al. The E3 ubiquitin ligase UBE3C enhances proteasome processivity by ubiquitinating partially proteolyzed substrates. J Biol Chem 288:34575-87 (2013). WB ; Human . PubMed: 24158444
  • de Poot SA  et al. Granzyme M targets topoisomerase II alpha to trigger cell cycle arrest and caspase-dependent apoptosis. Cell Death Differ N/A:N/A (2013). PubMed: 24185622
  • Banyard J  et al. Regulation of epithelial plasticity by miR-424 and miR-200 in a new prostate cancer metastasis model. Sci Rep 3:3151 (2013). WB . PubMed: 24193225
  • Snyder NW  et al. Cellular uptake and antiproliferative effects of 11-oxo-eicosatetraenoic acid. J Lipid Res 54:3070-7 (2013). PubMed: 23945567
  • Kansara M  et al. Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation. J Clin Invest 123:5351-60 (2013). WB ; Human . PubMed: 24231354
  • Hardee J  et al. STAT3 targets suggest mechanisms of aggressive tumorigenesis in diffuse large B-cell lymphoma. G3 (Bethesda) 3:2173-85 (2013). WB . PubMed: 24142927
  • Yoshihara D  et al. Telmisartan ameliorates fibrocystic liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease. PLoS One 8:e81480 (2013). WB ; Rat . PubMed: 24324698
  • Phillip CJ  et al. Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines. J Hematol Oncol 6:92 (2013). WB ; Human . PubMed: 24326130
  • Bennett BT  et al. Effects of resveratrol on the recovery of muscle mass following disuse in the plantaris muscle of aged rats. PLoS One 8:e83518 (2013). WB ; Rat . PubMed: 24349525
  • Ding J  et al. Inhibition of PI3K/mTOR overcomes nilotinib resistance in BCR-ABL1 positive leukemia cells through translational down-regulation of MDM2. PLoS One 8:e83510 (2013). WB ; Human . PubMed: 24349524
  • Lorenz S  et al. Functional analysis of a duplication (p.E63_D69dup) in the switch II region of HRAS: new aspects of the molecular pathogenesis underlying Costello syndrome. Hum Mol Genet 22:1643-53 (2013). PubMed: 23335589
  • Ishida E  et al. Thyroid hormone receptor and liver X receptor competitively up-regulate human selective Alzheimer's disease indicator-1 gene expression at the transcriptional levels. Biochem Biophys Res Commun 432:513-8 (2013). PubMed: 23416078
  • Hambleton S  et al. STAT2 deficiency and susceptibility to viral illness in humans. Proc Natl Acad Sci U S A 110:3053-8 (2013). PubMed: 23391734
  • Farhang Ghahremani M  et al. p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway. Cell Death Differ 20:888-97 (2013). PubMed: 23449391
  • Ling LS  et al. Activation of PDK-1 maintains mouse embryonic stem cell self-renewal in a PKB-dependent manner. Oncogene 32:5397-408 (2013). PubMed: 23455320
  • Wang AH  et al. The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis. EMBO J 32:1075-86 (2013). WB ; Mouse . PubMed: 23503590
  • Han G  et al. Preventive and therapeutic effects of Smad7 on radiation-induced oral mucositis. Nat Med 19:421-8 (2013). WB . PubMed: 23475202
  • Nohata N  et al. Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma. Br J Cancer 108:1648-58 (2013). PubMed: 23558898
  • Bubenik JL  et al. Alternative transcripts and 3'UTR elements govern the incorporation of selenocysteine into selenoprotein S. PLoS One 8:e62102 (2013). WB ; Human . PubMed: 23614019
  • Valle BL  et al. Non-steroidal anti-inflammatory drugs decrease E2F1 expression and inhibit cell growth in ovarian cancer cells. PLoS One 8:e61836 (2013). Human . PubMed: 23637916
  • Brachvogel B  et al. Comparative proteomic analysis of normal and collagen IX null mouse cartilage reveals altered extracellular matrix composition and novel components of the collagen IX interactome. J Biol Chem 288:13481-92 (2013). WB ; Mouse . PubMed: 23530037
  • Parone PA  et al. Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis. J Neurosci 33:4657-71 (2013). PubMed: 23486940
  • Orenstein SJ  et al. Interplay of LRRK2 with chaperone-mediated autophagy. Nat Neurosci 16:394-406 (2013). WB . PubMed: 23455607
  • Hsiao HM  et al. A novel anti-inflammatory and pro-resolving role for resolvin D1 in acute cigarette smoke-induced lung inflammation. PLoS One 8:e58258 (2013). WB ; Human . PubMed: 23484005
  • Arnold ES  et al. ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43. Proc Natl Acad Sci U S A 110:E736-45 (2013). WB ; Mouse . PubMed: 23382207
  • Du M  et al. SB225002 promotes mitotic catastrophe in chemo-sensitive and -resistant ovarian cancer cells independent of p53 status in vitro. PLoS One 8:e54572 (2013). WB ; Human . PubMed: 23359652
  • Mahendram S  et al. Ectopic ?-catenin expression partially mimics the effects of stabilized ß-catenin on embryonic stem cell differentiation. PLoS One 8:e65320 (2013). Mouse . PubMed: 23724138
  • Kulkarni AA  et al. The Triterpenoid CDDO-Me Inhibits Bleomycin-Induced Lung Inflammation and Fibrosis. PLoS One 8:e63798 (2013). WB ; Mouse . PubMed: 23741300
  • Bargagna-Mohan P  et al. Withaferin A effectively targets soluble vimentin in the glaucoma filtration surgical model of fibrosis. PLoS One 8:e63881 (2013). WB ; Rabbit . PubMed: 23667686
  • Yamamoto N  et al. Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion by targeting focal adhesion pathways in cervical squamous cell carcinoma. Int J Oncol 42:1523-32 (2013). WB . PubMed: 23483249
  • Hara S  et al. Serine 129 phosphorylation of membrane-associated a-synuclein modulates dopamine transporter function in a G protein-coupled receptor kinase-dependent manner. Mol Biol Cell 24:1649-60, S1-3 (2013). WB ; Human . PubMed: 23576548
  • Tarran R  et al. Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion. Am J Physiol Lung Cell Mol Physiol 304:L746-56 (2013). PubMed: 23542952
  • Wang GM  et al. Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation. Cancer Res 73:3248-61 (2013). PubMed: 23580570
  • Wang Y  et al. 7,8-Dihydroxycoumarin inhibits A549 human lung adenocarcinoma cell proliferation by inducing apoptosis via suppression of Akt/NF-?B signaling. Exp Ther Med 5:1770-1774 (2013). WB ; Human . PubMed: 23837071
  • Ikeda T  et al. Soluble CD26/Dipeptidyl Peptidase IV Enhances the Transcription of IL-6 and TNF-a in THP-1 Cells and Monocytes. PLoS One 8:e66520 (2013). PubMed: 23805228
  • Rahman MS  et al. Rickettsia typhi possesses phospholipase A2 enzymes that are involved in infection of host cells. PLoS Pathog 9:e1003399 (2013). PubMed: 23818842
  • Long DA  et al. Albuminuria is associated with too few glomeruli and too much testosterone. Kidney Int 83:1118-29 (2013). WB ; Mouse . PubMed: 23447063
  • Stadler SC  et al. Dysregulation of PAD4-mediated citrullination of nuclear GSK3ß activates TGF-ß signaling and induces epithelial-to-mesenchymal transition in breast cancer cells. Proc Natl Acad Sci U S A 110:11851-6 (2013). PubMed: 23818587
  • Larabee JL  et al. Increased cAMP in monocytes augments Notch signaling mechanisms by elevating RBP-J and transducin-like enhancer of Split (TLE). J Biol Chem 288:21526-36 (2013). PubMed: 23775085
  • Chen YT  et al. Anterior gradient 2: A novel sensitive tumor marker for metastatic oral cancer. Cancer Lett 339:270-8 (2013). PubMed: 23834814
  • Fachinetti D  et al. A two-step mechanism for epigenetic specification of centromere identity and function. Nat Cell Biol 15:1056-66 (2013). PubMed: 23873148
  • Pernet V  et al. Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve. Cell Death Dis 4:e734 (2013). WB ; Mouse . PubMed: 23868067
  • Totonchy JE  et al. Aberrant proliferation in CXCR7+ endothelial cells via degradation of the retinoblastoma protein. PLoS One 8:e69828 (2013). PubMed: 23894550
  • Amako Y  et al. Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis. J Biol Chem 288:24753-63 (2013). WB ; Human . PubMed: 23857585
  • Lukas J  et al. Functional characterisation of alpha-galactosidase a mutations as a basis for a new classification system in fabry disease. PLoS Genet 9:e1003632 (2013). WB ; Human . PubMed: 23935525
  • Gyöngyösi A  et al. RDH10, RALDH2, and CRABP2 are required components of PPAR?-directed ATRA synthesis and signaling in human dendritic cells. J Lipid Res 54:2458-74 (2013). PubMed: 23833249
  • Poulos MG  et al. Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice. Hum Mol Genet 22:3547-58 (2013). PubMed: 23660517
  • Murholm M  et al. Retinoic acid has different effects on UCP1 expression in mouse and human adipocytes. BMC Cell Biol 14:41 (2013). PubMed: 24059847
  • Sartori R  et al. BMP signaling controls muscle mass. Nat Genet 45:1309-18 (2013). PubMed: 24076600
  • Garg N  et al. microRNA-17-92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1. EMBO J 32:2819-32 (2013). WB ; Mouse . PubMed: 24076654
  • Suzuki Y  et al. Human copper chaperone for superoxide dismutase 1 mediates its own oxidation-dependent import into mitochondria. Nat Commun 4:2430 (2013). PubMed: 24026195
  • Murk K  et al. The antagonistic modulation of Arp2/3 activity by N-WASP, WAVE2 and PICK1 defines dynamic changes in astrocyte morphology. J Cell Sci 126:3873-83 (2013). PubMed: 23843614
  • Meng Y  et al. Downregulated expression of peroxiredoxin 4 in granulosa cells from polycystic ovary syndrome. PLoS One 8:e76460 (2013). WB ; Human . PubMed: 24098506
  • Ebsen H  et al. Differential Surface Expression of ADAM10 and ADAM17 on Human T Lymphocytes and Tumor Cells. PLoS One 8:e76853 (2013). WB ; Human . PubMed: 24130797
  • Dave JM  et al. Proteomic Profiling of Endothelial Invasion Revealed Receptor for Activated C Kinase 1 (RACK1) Complexed with Vimentin to Regulate Focal Adhesion Kinase (FAK). J Biol Chem 288:30720-33 (2013). WB ; Human . PubMed: 24005669
  • Xiong ZM  et al. An inhibitory role of progerin in the gene induction network of adipocyte differentiation from iPS cells. Aging (Albany NY) 5:288-303 (2013). WB ; Human . PubMed: 23596277
  • Neyret-Kahn H  et al. Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation. Genome Res 23:1563-79 (2013). PubMed: 23893515
  • Taylor-Weiner H  et al. Defined extracellular matrix components are necessary for definitive endoderm induction. Stem Cells 31:2084-94 (2013). WB ; Mouse . PubMed: 23766144
  • Hobai IA  et al. SERCA Cys674 sulphonylation and inhibition of L-type Ca2+ influx contribute to cardiac dysfunction in endotoxemic mice, independent of cGMP synthesis. Am J Physiol Heart Circ Physiol 305:H1189-200 (2013). PubMed: 23934853
  • Holle AW  et al. In situ mechanotransduction via vinculin regulates stem cell differentiation. Stem Cells 31:2467-77 (2013). ICC/IF ; Human . PubMed: 23897765
  • Li T  et al. Ectopic overexpression of porcine DGAT1 increases intramuscular fat content in mouse skeletal muscle. Transgenic Res 22:187-94 (2013). PubMed: 22826105
  • Gai L  et al. Ursolic acid induces apoptosis via Akt/NF-?B signaling suppression in T24 human bladder cancer cells. Mol Med Rep 7:1673-7 (2013). PubMed: 23483134
  • Fantin M  et al. A key role for nectin-1 in the ventral hippocampus in contextual fear memory. PLoS One 8:e56897 (2013). PubMed: 23418609
  • Sanchez N  et al. MiR-7 triggers cell cycle arrest at the G1/S transition by targeting multiple genes including Skp2 and Psme3. PLoS One 8:e65671 (2013). WB ; Human . PubMed: 23762407
  • Yamamoto N  et al. Tumor-suppressive microRNA-29a inhibits cancer cell migration and invasion via targeting HSP47 in cervical squamous cell carcinoma. Int J Oncol 43:1855-63 (2013). WB . PubMed: 24141696
  • Vidyasagar A  et al. Tubular expression of heat-shock protein 27 inhibits fibrogenesis in obstructive nephropathy. Kidney Int 83:84-92 (2013). WB . PubMed: 22971995
  • Jackson TR  et al. DNA damage causes TP53-dependent coupling of self-renewal and senescence pathways in embryonal carcinoma cells. Cell Cycle 12:430-41 (2013). PubMed: 23287532
  • Lu Q  et al. Increased NADPH oxidase-derived superoxide is involved in the neuronal cell death induced by hypoxia-ischemia in neonatal hippocampal slice cultures. Free Radic Biol Med 53:1139-51 (2012). PubMed: 22728269
  • Tanida I  et al. The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation. Autophagy 8:88-97 (2012). PubMed: 22170151
  • Vázquez P  et al. Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells. Autophagy 8:187-99 (2012). PubMed: 22240590
  • Vrazo AC  et al. Epstein-Barr virus LMP2A reduces hyperactivation induced by LMP1 to restore normal B cell phenotype in transgenic mice. PLoS Pathog 8:e1002662 (2012). PubMed: 22536156
  • Kinoshita T  et al. Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma. Oncotarget 3:1386-400 (2012). WB . PubMed: 23159910
  • Hsieh YL  et al. Dry needling at myofascial trigger spots of rabbit skeletal muscles modulates the biochemicals associated with pain, inflammation, and hypoxia. Evid Based Complement Alternat Med 2012:342165 (2012). WB ; Rabbit . PubMed: 23346198
  • Isozaki Y  et al. Identification of novel molecular targets regulated by tumor suppressive miR-375 induced by histone acetylation in esophageal squamous cell carcinoma. Int J Oncol 41:985-94 (2012). PubMed: 22752059
  • Watson CP  et al. The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: evidence for involvement of breast cancer resistance protein. Brain Res 1436:111-21 (2012). WB . PubMed: 22200378
  • Kinoshita T  et al. Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma. Int J Oncol 40:1770-8 (2012). PubMed: 22378351
  • Tran TH  et al. Heparan sulfate 6-O-endosulfatases (Sulfs) coordinate the Wnt signaling pathways to regulate myoblast fusion during skeletal muscle regeneration. J Biol Chem 287:32651-64 (2012). PubMed: 22865881
  • Sigoillot FD  et al. A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens. Nat Methods 9:363-6 (2012). PubMed: 22343343
  • Kinoshita T  et al. Tumor suppressive microRNA-375 regulates lactate dehydrogenase B in maxillary sinus squamous cell carcinoma. Int J Oncol 40:185-93 (2012). PubMed: 21922130
  • Kovacevic I  et al. The F-BAR protein NOSTRIN participates in FGF signal transduction and vascular development. EMBO J 31:3309-22 (2012). PubMed: 22751148
  • McEvoy J  et al. Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma. PLoS One 7:e42739 (2012). WB . PubMed: 22916154
  • Wang R  et al. Role of transcriptional corepressor CtBP1 in prostate cancer progression. Neoplasia 14:905-14 (2012). PubMed: 23097625
  • Yao M  et al. How can food extracts consumed in the Mediterranean and East Asia suppress prostate cancer proliferation? Br J Nutr 108:424-30 (2012). WB ; Human . PubMed: 22067725
  • Schulz R  et al. Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression. J Exp Med 209:275-89 (2012). PubMed: 22271573
  • Luo J  et al. Role of FYN kinase in spermatogenesis: defects characteristic of Fyn-null sperm in mice. Biol Reprod 86:1-8 (2012). PubMed: 21918125
  • Kühbacher A  et al. Phosphatidylinositol 5-phosphatase oculocerebrorenal syndrome of Lowe protein (OCRL) controls actin dynamics during early steps of Listeria monocytogenes infection. J Biol Chem 287:13128-36 (2012). WB . PubMed: 22351770
  • Sakellariou G  et al. Studies of mitochondrial and non-mitochondrial sources implicate NADPH oxidase(s) in the increased skeletal muscle superoxide generation that occurs during contractile activity. Antioxid Redox Signal : (2012). WB ; Mouse . PubMed: 23050834
  • Ma H  et al. Human annexin A6 interacts with influenza a virus protein M2 and negatively modulates infection. J Virol 86:1789-801 (2012). PubMed: 22114333
  • Lerner M  et al. MiR-200c regulates Noxa expression and sensitivity to proteasomal inhibitors. PLoS One 7:e36490 (2012). WB . PubMed: 22615771
  • Wang Y  et al. Cardioprotective Effects of Qishenyiqi Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin-Converting Enzyme 2. Evid Based Complement Alternat Med 2012:978127 (2012). WB ; Rat . PubMed: 23304234
  • Elrick MJ  et al. Impaired proteolysis underlies autophagic dysfunction in Niemann-Pick type C disease. Hum Mol Genet 21:4876-87 (2012). PubMed: 22872701
  • Lagier-Tourenne C  et al. Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs. Nat Neurosci 15:1488-97 (2012). WB . PubMed: 23023293
  • Mozzetti S  et al. Gli family transcription factors are drivers of patupilone resistance in ovarian cancer. Biochem Pharmacol 84:1409-18 (2012). PubMed: 22964220
  • Kästle M  et al. Histone deacetylase 6 (HDAC6) plays a crucial role in p38MAPK-dependent induction of heme oxygenase-1 (HO-1) in response to proteasome inhibition. Free Radic Biol Med : (2012). PubMed: 23010497
  • Baseler WA  et al. miR-141 as a regulator of the mitochondrial phosphate carrier (Slc25a3) in the type 1 diabetic heart. Am J Physiol Cell Physiol 303:C1244-51 (2012). PubMed: 23034391
  • Hall ME  et al. Cardiomyocyte-specific deletion of leptin receptors causes lethal heart failure in Cre-recombinase-mediated cardiotoxicity. Am J Physiol Regul Integr Comp Physiol 303:R1241-50 (2012). PubMed: 23115124
  • Kato D  et al. Phosphorylation of human INO80 is involved in DNA damage tolerance. Biochem Biophys Res Commun 417:433-8 (2012). PubMed: 22166198
  • Cioffi M  et al. EpCAM/CD3-Bispecific T-cell engaging antibody MT110 eliminates primary human pancreatic cancer stem cells. Clin Cancer Res 18:465-74 (2012). WB ; Human . PubMed: 22096026
  • Emo J  et al. Lpa2 is a negative regulator of both dendritic cell activation and murine models of allergic lung inflammation. J Immunol 188:3784-90 (2012). WB ; Mouse . PubMed: 22427635
  • Shapiro-Reznik M  et al. Diurnal rhythms in neurexins transcripts and inhibitory/excitatory synapse scaffold proteins in the biological clock. PLoS One 7:e37894 (2012). WB ; Mouse . PubMed: 22662246
  • Genead R  et al. Ischemia-reperfusion injury and pregnancy initiate time-dependent and robust signs of up-regulation of cardiac progenitor cells. PLoS One 7:e36804 (2012). WB ; Rat . PubMed: 22590612
  • Huyghe A  et al. Developmental Splicing Deregulation in Leukodystrophies Related to EIF2B Mutations. PLoS One 7:e38264 (2012). WB ; Human . PubMed: 22737209
  • O'Leary MF  et al. Denervation-induced mitochondrial dysfunction and autophagy in skeletal muscle of apoptosis-deficient animals. Am J Physiol Cell Physiol 303:C447-54 (2012). WB ; Mouse . PubMed: 22673615
  • Li T  et al. STIM1-Ca(2+) signaling is required for the hypertrophic growth of skeletal muscle in mice. Mol Cell Biol 32:3009-17 (2012). WB ; Mouse . PubMed: 22645307
  • Adam O  et al. Role of miR-21 in the pathogenesis of atrial fibrosis. Basic Res Cardiol 107:278 (2012). PubMed: 22760500
  • Corrêa SA  et al. MSK1 regulates homeostatic and experience-dependent synaptic plasticity. J Neurosci 32:13039-51 (2012). PubMed: 22993422
  • Zou L  et al. Glucose deprivation-induced increase in protein O-GlcNAcylation in cardiomyocytes is calcium-dependent. J Biol Chem 287:34419-31 (2012). PubMed: 22908225
  • Moriya Y  et al. Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma. J Hum Genet 57:38-45 (2012). PubMed: 22089643
  • Gripp KW  et al. A novel HRAS substitution (c.266C>G; p.S89C) resulting in decreased downstream signaling suggests a new dimension of RAS pathway dysregulation in human development. Am J Med Genet A 158A:2106-18 (2012). PubMed: 22821884
  • Grimm M  et al. ABCB5 expression and cancer stem cell hypothesis in oral squamous cell carcinoma. Eur J Cancer 48:3186-97 (2012). PubMed: 22784549
  • Wang Y  et al. Drug target prediction based on the herbs components: the study on the multitargets pharmacological mechanism of qishenkeli acting on the coronary heart disease. Evid Based Complement Alternat Med 2012:698531 (2012). PubMed: 22474514
  • Sarajärvi T  et al. Bepridil decreases Aß and calcium levels in the thalamus after middle cerebral artery occlusion in rats. J Cell Mol Med 16:2754-67 (2012). WB . PubMed: 22805236
  • Marazita MC  et al. CDK2 and PKA mediated-sequential phosphorylation is critical for p19INK4d function in the DNA damage response. PLoS One 7:e35638 (2012). PubMed: 22558186
  • Boone DR  et al. Traumatic brain injury-induced dysregulation of the circadian clock. PLoS One 7:e46204 (2012). PubMed: 23056261
  • Ucar A  et al. The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy. Nat Commun 3:1078 (2012). PubMed: 23011132
  • Djamali A  et al. Nox2 is a mediator of chronic CsA nephrotoxicity. Am J Transplant 12:1997-2007 (2012). PubMed: 22568654
  • Mendez-Figueroa H  et al. Effects of Labor on Placental Fatty Acid Beta Oxidation. J Matern Fetal Neonatal Med : (2012). PubMed: 22928498
  • Savickiene J  et al. Antileukemic activity of combined epigenetic agents, DNMT inhibitors zebularine and RG108 with HDAC inhibitors, against promyelocytic leukemia HL-60 cells. Cell Mol Biol Lett 17:501-25 (2012). PubMed: 22820861
  • Mori M  et al. Essential Role for miR-196a in Brown Adipogenesis of White Fat Progenitor Cells. PLoS Biol 10:e1001314 (2012). WB . PubMed: 22545021
  • Wilbert ML  et al. LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance. Mol Cell 48:195-206 (2012). PubMed: 22959275
  • Wang Q  et al. The intracellular transport and secretion of calumenin-1/2 in living cells. PLoS One 7:e35344 (2012). PubMed: 22514732
  • Arnandis T  et al. Calpains mediate epithelial-cell death during mammary gland involution: mitochondria and lysosomal destabilization. Cell Death Differ : (2012). PubMed: 22555453
  • Galicia-Vázquez G  et al. A cellular response linking eIF4AI activity to eIF4AII transcription. RNA 18:1373-84 (2012). WB . PubMed: 22589333
  • Izumi N  et al. Heat shock protein 90 regulates phosphatidylinositol 3-kinase-related protein kinase family proteins together with the RUVBL1/2 and Tel2-containing co-factor complex. Cancer Sci 103:50-7 (2012). PubMed: 21951644
  • Lin J  et al. ADAM17 overexpression promotes angiogenesis by increasing blood vessel sprouting and pericyte number during brain microvessel development. Int J Dev Biol 55:961-8 (2011). PubMed: 22252493
  • Su S  et al. Proteomic analysis of human age-related nuclear cataracts and normal lens nuclei. Invest Ophthalmol Vis Sci 52:4182-91 (2011). PubMed: 21436267
  • Kugita M  et al. Global gene expression profiling in early-stage polycystic kidney disease in the Han:SPRD Cy rat identifies a role for RXR signaling. Am J Physiol Renal Physiol 300:F177-88 (2011). PubMed: 20926632
  • Pulipati NR  et al. Overexpression of the dynein light chain km23-1 in human ovarian carcinoma cells inhibits tumor formation in vivo and causes mitotic delay at prometaphase/metaphase. Int J Cancer 129:553-64 (2011). PubMed: 21469138
  • Provenzano MJ  et al. p75(NTR) expression and nuclear localization of p75(NTR) intracellular domain in spiral ganglion Schwann cells following deafness correlate with cell proliferation. Mol Cell Neurosci 47:306-15 (2011). PubMed: 21658451
  • Fraccarollo D  et al. Deletion of cardiomyocyte mineralocorticoid receptor ameliorates adverse remodeling after myocardial infarction. Circulation 123:400-8 (2011). WB . PubMed: 21242479
  • Viswanathan J  et al. Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation. Traffic 12:330-48 (2011). PubMed: 21143716
  • Wullschleger S  et al. Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis. Biochem J 434:265-74 (2011). PubMed: 21204784
  • Radzikinas K  et al. A Shh/miR-206/BDNF cascade coordinates innervation and formation of airway smooth muscle. J Neurosci 31:15407-15 (2011). PubMed: 22031887
  • Meleady P  et al. Sustained productivity in recombinant Chinese hamster ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype. BMC Biotechnol 11:78 (2011). WB . PubMed: 21781345
  • Wu W  et al. Characterization of the interaction between human respiratory syncytial virus and the cell cycle in continuous cell culture and primary human airway epithelial cells. J Virol 85:10300-9 (2011). PubMed: 21795354
  • Al-Bahlani S  et al. P73 regulates cisplatin-induced apoptosis in ovarian cancer cells via a calcium/calpain-dependent mechanism. Oncogene 30:4219-30 (2011). PubMed: 21516125
  • Crist RC  et al. A conserved tissue-specific homeodomain-less isoform of MEIS1 is downregulated in colorectal cancer. PLoS One 6:e23665 (2011). WB ; Mouse . PubMed: 21858198
  • Kulkarni AA  et al. PPAR-? ligands repress TGFß-induced myofibroblast differentiation by targeting the PI3K/Akt pathway: implications for therapy of fibrosis. PLoS One 6:e15909 (2011). WB ; Human . PubMed: 21253589
  • Sarajärvi T  et al. Cysteine 27 Variant of the {delta}-Opioid Receptor Affects Amyloid Precursor Protein Processing through Altered Endocytic Trafficking. Mol Cell Biol 31:2326-40 (2011). WB . PubMed: 21464208
  • Kapoor-Vazirani P  et al. SUV420H2-mediated H4K20 trimethylation enforces RNA polymerase II promoter-proximal pausing by blocking hMOF-dependent H4K16 acetylation. Mol Cell Biol 31:1594-609 (2011). PubMed: 21321083
  • Gregory-Evans CY  et al. Gene-specific differential response to anti-apoptotic therapies in zebrafish models of ocular coloboma. Mol Vis 17:1473-84 (2011). WB ; Zebrafish . PubMed: 21677791
  • Kitamura K  et al. Eicosapentaenoic acid prevents atrial fibrillation associated with heart failure in a rabbit model. Am J Physiol Heart Circ Physiol 300:H1814-21 (2011). PubMed: 21335470
  • Thum T  et al. Impairment of endothelial progenitor cell function and vascularization capacity by aldosterone in mice and humans. Eur Heart J 32:1275-86 (2011). PubMed: 20926363
  • Liang XH & Crooke ST Depletion of key protein components of the RISC pathway impairs pre-ribosomal RNA processing. Nucleic Acids Res : (2011). PubMed: 21321021
  • Larabee JL  et al. Adenomatous polyposis coli protein associates with C/EBP beta and increases Bacillus anthracis edema toxin-stimulated gene expression in macrophages. J Biol Chem 286:19364-72 (2011). PubMed: 21487015
  • Nakken B  et al. Peroxisome proliferator-activated receptor ?-regulated cathepsin D is required for lipid antigen presentation by dendritic cells. J Immunol 187:240-7 (2011). WB . PubMed: 21632707
  • Muniz VP  et al. The ARF tumor suppressor inhibits tumor cell colonization independent of p53 in a novel mouse model of pancreatic ductal adenocarcinoma metastasis. Mol Cancer Res 9:867-77 (2011). WB . PubMed: 21636682
  • Tserel L  et al. MicroRNA Expression Profiles of Human Blood Monocyte-derived Dendritic Cells and Macrophages Reveal miR-511 as Putative Positive Regulator of Toll-like Receptor 4. J Biol Chem 286:26487-95 (2011). WB ; Human . PubMed: 21646346
  • Sato H  et al. Authentically phosphorylated a-synuclein at Ser129 accelerates neurodegeneration in a rat model of familial Parkinson's disease. J Neurosci 31:16884-94 (2011). PubMed: 22090514
  • Jones DM  et al. A genetic interaction between the core and NS3 proteins of hepatitis C virus is essential for production of infectious virus. J Virol 85:12351-61 (2011). PubMed: 21957313
  • Fiedler J  et al. MicroRNA-24 regulates vascularity after myocardial infarction. Circulation 124:720-30 (2011). WB, IHC-Fr ; Mouse . PubMed: 21788589
  • Hvid H  et al. In situ phosphorylation of Akt and ERK1/2 in rat mammary gland, colon, and liver following treatment with human insulin and IGF-1. Toxicol Pathol 39:623-40 (2011). PubMed: 21558470
  • Peterson SM  et al. Global gene expression analysis reveals dynamic and developmental stage-dependent enrichment of lead-induced neurological gene alterations. Environ Health Perspect 119:615-21 (2011). PubMed: 21147602
  • Hall ME  et al. Systolic dysfunction in cardiac-specific ligand-inducible MerCreMer transgenic mice. Am J Physiol Heart Circ Physiol 301:H253-60 (2011). PubMed: 21536850
  • Rettberg JR  et al. The effect of dietary soy isoflavones before and after ovariectomy on hippocampal protein markers of mitochondrial bioenergetics and antioxidant activity in female monkeys. Brain Res 1379:23-33 (2011). PubMed: 21238431
  • Nagajyothi F  et al. Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion. PLoS Negl Trop Dis 5:e953 (2011). WB . PubMed: 21408103
  • Higgins MJ  et al. PIK3CA mutations and EGFR overexpression predict for lithium sensitivity in human breast epithelial cells. Cancer Biol Ther 11:358-67 (2011). PubMed: 21124076
  • Wang ML  et al. Gene expression signature of c-MYC-immortalized human fibroblasts reveals loss of growth inhibitory response to TGFß. Cell Cycle 10:2540-8 (2011). PubMed: 21720214
  • Magnani I  et al. Differential signature of the centrosomal MARK4 isoforms in glioma. Anal Cell Pathol (Amst) 34:319-38 (2011). PubMed: 22156016
  • Polymenidou M  et al. Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. Nat Neurosci 14:459-68 (2011). WB . PubMed: 21358643
  • Satish L  et al. Chaperonin containing T-complex polypeptide (CCT) subunit expression in oral mucosal wounds and fibroblasts. Cell Stress Chaperones 16:675-80 (2011). PubMed: 21710295
  • Keck-Wherley J  et al. Abnormal microRNA expression in Ts65Dn hippocampus and whole blood: contributions to Down syndrome phenotypes. Dev Neurosci 33:451-67 (2011). PubMed: 22042248
  • Hamilton RT  et al. Hippocampal responsiveness to 17ß-estradiol and equol after long-term ovariectomy: implication for a therapeutic window of opportunity. Brain Res 1379:11-22 (2011). PubMed: 21241683
  • Miniard AC  et al. Nucleolin binds to a subset of selenoprotein mRNAs and regulates their expression. Nucleic Acids Res 38:4807-20 (2010). WB . PubMed: 20385601
  • Alexaki VI  et al. GLI2-mediated melanoma invasion and metastasis. J Natl Cancer Inst 102:1148-59 (2010). PubMed: 20660365
  • Rafiqi FH  et al. Role of the WNK-activated SPAK kinase in regulating blood pressure. EMBO Mol Med 2:63-75 (2010). PubMed: 20091762
  • Gastaldello A  et al. Ca 2+ -dependent autophagy is enhanced by the pharmacological agent PK11195. Autophagy 6:607-13 (2010). PubMed: 20431351
  • Rutanen J  et al. SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity. Diabetes 59:829-35 (2010). PubMed: 20107110
  • Salmeen A  et al. The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway. Oncogene 29:4473-84 (2010). WB . PubMed: 20531308
  • Yamaji M  et al. Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3. Reproduction 139:381-93 (2010). PubMed: 19861488
  • Emblom-Callahan MC  et al. Genomic phenotype of non-cultured pulmonary fibroblasts in idiopathic pulmonary fibrosis. Genomics 96:134-45 (2010). WB ; Human . PubMed: 20451601
  • Schäfer A  et al. Increased cytochrome P4502E1 expression and altered hydroxyeicosatetraenoic acid formation mediate diabetic vascular dysfunction: rescue by guanylyl-cyclase activation. Diabetes 59:2001-9 (2010). WB ; Rat . PubMed: 20522591
  • Ma CH  et al. Synergistic effects of osteonectin and brain-derived neurotrophic factor on axotomized retinal ganglion cells neurite outgrowth via the mitogen-activated protein kinase-extracellular signal-regulated kinase 1/2 pathways. Neuroscience 165:463-74 (2010). WB ; Rat . PubMed: 19837135
  • Schaff UY  et al. Orai1 regulates intracellular calcium, arrest, and shape polarization during neutrophil recruitment in shear flow. Blood 115:657-66 (2010). ICC/IF . PubMed: 19965684
  • Bonnesen C  et al. Synchronization in G0/G1 enhances the mitogenic response of cells overexpressing the human insulin receptor A isoform to insulin. Cell Biol Toxicol 26:293-307 (2010). WB ; Rat . PubMed: 19898946
  • Haubold M  et al. Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cells. Int J Biol Sci 6:700-15 (2010). WB ; Human . PubMed: 21152263
  • Yang X  et al. Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma. J Proteome Res 9:1402-15 (2010). WB, ICC/IF ; Human . PubMed: 20000738
  • Martin D  et al. Sequestration of free tubulin molecules by the viral protein NSP2 induces microtubule depolymerization during rotavirus infection. J Virol 84:2522-32 (2010). PubMed: 20032187
  • Clauss A  et al. Overexpression of elafin in ovarian carcinoma is driven by genomic gains and activation of the nuclear factor kappaB pathway and is associated with poor overall survival. Neoplasia 12:161-72 (2010). WB . PubMed: 20126474
  • Joset A  et al. Pincher-generated Nogo-A endosomes mediate growth cone collapse and retrograde signaling. J Cell Biol 188:271-85 (2010). WB ; Rat . PubMed: 20083601
  • Elrick MJ  et al. Conditional Niemann-Pick C mice demonstrate cell autonomous Purkinje cell neurodegeneration. Hum Mol Genet 19:837-47 (2010). WB ; Mouse . PubMed: 20007718
  • Johnson KE & Knipe DM Herpes simplex virus-1 infection causes the secretion of a type I interferon-antagonizing protein and inhibits signaling at or before Jak-1 activation. Virology 396:21-9 (2010). WB ; African green monkey . PubMed: 19879619
  • Abend JR  et al. Global effects of BKV infection on gene expression in human primary kidney epithelial cells. Virology 397:73-9 (2010). WB . PubMed: 19945725
  • Abedini MR  et al. Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein. Oncogene 29:11-25 (2010). WB . PubMed: 19802016
  • Lauring J  et al. Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations. Oncogene : (2010). WB ; Human . PubMed: 20101210
  • Vinken M  et al. Connexin32 hemichannels contribute to the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death. Cell Mol Life Sci 67:907-18 (2010). WB ; Rat . PubMed: 19960225
  • Enikanolaiye A  et al. Involucrin-claudin-6 tail deletion mutant (CDelta206) transgenic mice: a model of delayed epidermal permeability barrier formation and repair. Dis Model Mech 3:167-80 (2010). WB ; Mouse . PubMed: 20106878
  • Liefke R  et al. Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex. Genes Dev 24:590-601 (2010). WB ; Mouse . PubMed: 20231316
  • Stellrecht CM  et al. A unique RNA-directed nucleoside analog is cytotoxic to breast cancer cells and depletes cyclin E levels. Breast Cancer Res Treat 121:355-64 (2010). WB ; Human . PubMed: 19641990
  • Read EK & Digard P Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export. J Gen Virol 91:1290-301 (2010). WB, In situ hybridization ; Human . PubMed: 20071484
  • Luthi-Carter R  et al. SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis. Proc Natl Acad Sci U S A 107:7927-32 (2010). WB ; Human . PubMed: 20378838
  • McCarroll JA  et al. betaIII-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer. Cancer Res 70:4995-5003 (2010). WB ; Human . PubMed: 20501838
  • Beronja S  et al. Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos. Nat Med 16:821-7 (2010). PubMed: 20526348
  • Wüstehube J  et al. Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling. Proc Natl Acad Sci U S A 107:12640-5 (2010). WB ; Human . PubMed: 20616044
  • Voss V  et al. The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma. Mol Cancer Res 8:1002-16 (2010). ICC/IF, WB ; Human . PubMed: 20587533
  • Wang Y  et al. Critical role for transcriptional repressor Snail2 in transformation by oncogenic RAS in colorectal carcinoma cells. Oncogene 29:4658-70 (2010). WB ; Human . PubMed: 20562906
  • Roussel-Gervais A  et al. Cooperation between Cyclin E and p27(Kip1) in pituitary tumorigenesis. Mol Endocrinol 24:1835-45 (2010). WB . PubMed: 20660298
  • Mertens-Walker I  et al. Gonadotropin-induced ovarian cancer cell migration and proliferation require extracellular signal-regulated kinase 1/2 activation regulated by calcium and protein kinase C{delta}. Endocr Relat Cancer 17:335-49 (2010). PubMed: 20215102
  • Brütsch R  et al. Integrin cytoplasmic domain-associated protein-1 attenuates sprouting angiogenesis. Circ Res 107:592-601 (2010). PubMed: 20616313
  • Thomson SE  et al. A novel primate model of delayed wound healing in diabetes: dysregulation of connective tissue growth factor. Diabetologia 53:572-83 (2010). IHC-P ; Baboon . PubMed: 20091023
  • Djamali A  et al. Mycophenolic acid may delay allograft fibrosis by inhibiting transforming growth factor-beta1-induced activation of Nox-2 through the nuclear factor-kappaB pathway. Transplantation 90:387-93 (2010). Rat . PubMed: 20548261
  • Fleissner F  et al. Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism. Circ Res 107:138-43 (2010). PubMed: 20489163
  • Reszka NJ  et al. Construction and properties of a herpes simplex virus 2 dl5-29 vaccine candidate strain encoding an HSV-1 virion host shutoff protein. Vaccine 28:2754-62 (2010). PubMed: 20117270
  • Russell D  et al. ERK involvement in resistance to apoptosis in keratinocytes with mutant keratin. J Invest Dermatol 130:671-81 (2010). PubMed: 19847192
  • Nagao S  et al. Polycystic kidney disease in Han:SPRD Cy rats is associated with elevated expression and mislocalization of SamCystin. Am J Physiol Renal Physiol 299:F1078-86 (2010). PubMed: 20719982
  • Su SC  et al. Annexin 2 Regulates Endothelial Morphogenesis by Controlling AKT Activation and Junctional Integrity. J Biol Chem 285:40624-34 (2010). PubMed: 20947498
  • Rinaldo CH  et al. 1-O-hexadecyloxypropyl cidofovir (CMX001) effectively inhibits polyomavirus BK replication in primary human renal tubular epithelial cells. Antimicrob Agents Chemother 54:4714-22 (2010). PubMed: 20713664
  • Satish L  et al. Chaperonin containing T-complex polypeptide subunit eta (CCT-eta) is a specific regulator of fibroblast motility and contractility. PLoS One 5:e10063 (2010). PubMed: 20442790
  • Cairns DM  et al. Muscle cells enhance resistance to pro-inflammatory cytokine-induced cartilage destruction. Biochem Biophys Res Commun 392:22-8 (2010). PubMed: 20043873
  • Cairns DM  et al. The role of muscle cells in regulating cartilage matrix production. J Orthop Res 28:529-36 (2010). PubMed: 19813241
  • Pelkonen A  et al. Stimulated dopamine overflow and alpha-synuclein expression in the nucleus accumbens core distinguish rats bred for differential ethanol preference. J Neurochem 114:1168-76 (2010). PubMed: 20533994
  • Ljubicic V  et al. Molecular basis for an attenuated mitochondrial adaptive plasticity in aged skeletal muscle. Aging (Albany NY) 1:818-30 (2009). PubMed: 20157569
  • Rutland C  et al. Knockdown of alpha myosin heavy chain disrupts the cytoskeleton and leads to multiple defects during chick cardiogenesis. J Anat 214:905-15 (2009). PubMed: 19538634
  • Baca Jones CC  et al. Rat cytomegalovirus infection depletes MHC II in bone marrow derived dendritic cells. Virology 388:78-90 (2009). PubMed: 19349057
  • Sarajärvi T  et al. Down-regulation of seladin-1 increases BACE1 levels and activity through enhanced GGA3 depletion during apoptosis. J Biol Chem 284:34433-43 (2009). PubMed: 19815556
  • Russwurm C  et al. Dual acylation of PDE2A splice variant 3: targeting to synaptic membranes. J Biol Chem 284:25782-90 (2009). PubMed: 19632989
  • Denton CP  et al. Inducible lineage-specific deletion of TbetaRII in fibroblasts defines a pivotal regulatory role during adult skin wound healing. J Invest Dermatol 129:194-204 (2009). PubMed: 18563179
  • Yamashita T  et al. Essential and synergistic roles of RP1 and RP1L1 in rod photoreceptor axoneme and retinitis pigmentosa. J Neurosci 29:9748-60 (2009). PubMed: 19657028
  • Ma CH & Taylor JS Trophic responsiveness of purified postnatal and adult rat retinal ganglion cells. Cell Tissue Res : (2009). WB . PubMed: 19936794
  • De Marchis ML  et al. A new molecular network comprising PU.1, interferon regulatory factor proteins and miR-342 stimulates ATRA-mediated granulocytic differentiation of acute promyelocytic leukemia cells. Leukemia 23:856-62 (2009). WB ; Human . PubMed: 19151778
  • Gibb S  et al. Interfering with Wnt signalling alters the periodicity of the segmentation clock. Dev Biol 330:21-31 (2009). WB ; Chicken . PubMed: 19272372
  • Listov-Saabye N  et al. MCF-7 human mammary adenocarcinoma cells exhibit augmented responses to human insulin on a collagen IV surface. J Appl Toxicol 29:470-7 (2009). WB . PubMed: 19338014
  • Pandey DP & Picard D miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA. Mol Cell Biol 29:3783-90 (2009). WB ; Human . PubMed: 19414598
  • Széles L  et al. 1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype. J Immunol 182:2074-83 (2009). WB . PubMed: 19201860
  • Paupe V  et al. Impaired nuclear Nrf2 translocation undermines the oxidative stress response in friedreich ataxia. PLoS ONE 4:e4253 (2009). WB ; Human . PubMed: 19158945
  • Natsume Y  et al. Protective effect of quercetin on ER stress caused by calcium dynamics dysregulation in intestinal epithelial cells. Toxicology 258:164-75 (2009). WB ; Human . PubMed: 19428936
  • Budiman ME  et al. Eukaryotic initiation factor 4a3 is a selenium-regulated RNA-binding protein that selectively inhibits selenocysteine incorporation. Mol Cell 35:479-89 (2009). WB ; Rat . PubMed: 19716792
  • Vinken M  et al. Biochemical characterisation of an in vitro model of hepatocellular apoptotic cell death. Altern Lab Anim 37:209-18 (2009). WB ; Mouse . PubMed: 19453217
  • Krementsov DN  et al. Tetraspanins regulate cell-to-cell transmission of HIV-1. Retrovirology 6:64 (2009). WB ; Human . PubMed: 19602278
  • Egerod FL  et al. PPAR alpha and PPAR gamma coactivation rapidly induces Egr-1 in the nuclei of the dorsal and ventral urinary bladder and kidney pelvis urothelium of rats. Toxicol Pathol 37:947-58 (2009). WB ; Rat . PubMed: 20008548
  • Rees-Unwin KS  et al. Ribosome-associated nucleophosmin 1: increased expression and shuttling activity distinguishes prognostic subtypes in chronic lymphocytic leukaemia. Br J Haematol : (2009). WB ; Human . PubMed: 19961478
  • di Tommaso A  et al. Residues in the alternative reading frame tumor suppressor that influence its stability and p53-independent activities. Exp Cell Res 315:1326-35 (2009). WB ; Human . PubMed: 19331830
  • Djamali A  et al. Nox-2 is a modulator of fibrogenesis in kidney allografts. Am J Transplant 9:74-82 (2009). PubMed: 18976289
  • Mahn K  et al. Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma. Proc Natl Acad Sci U S A 106:10775-80 (2009). PubMed: 19541629
  • Partheen K  et al. External validation suggests Integrin beta 3 as prognostic biomarker in serous ovarian adenocarcinomas. BMC Cancer 9:336 (2009). WB . PubMed: 19775429
  • Muñoz IM  et al. Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair. Mol Cell 35:116-27 (2009). PubMed: 19595721
  • Fraccarollo D  et al. Immediate mineralocorticoid receptor blockade improves myocardial infarct healing by modulation of the inflammatory response. Hypertension 51:905-14 (2008). WB . PubMed: 18299485
  • Spiliotis ET  et al. Epithelial polarity requires septin coupling of vesicle transport to polyglutamylated microtubules. J Cell Biol 180:295-303 (2008). WB ; Dog . PubMed: 18209106
  • De La Chesnaye E  et al. Fbxw15/Fbxo12J Is an F-Box Protein-Encoding Gene Selectively Expressed in Oocytes of the Mouse Ovary. Biol Reprod 78:714-25 (2008). WB ; African green monkey . PubMed: 18094359
  • Greenberg CC  et al. Krp1 (Sarcosin) promotes lateral fusion of myofibril assembly intermediates in cultured mouse cardiomyocytes. Exp Cell Res 314:1177-91 (2008). WB ; Mouse . PubMed: 18178185
  • Richardson C  et al. Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1. J Cell Sci 121:675-84 (2008). WB ; Human . PubMed: 18270262
  • Bhaskara S  et al. Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control. Mol Cell 30:61-72 (2008). WB ; Mouse . PubMed: 18406327
  • Knutson SK  et al. Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks. EMBO J 27:1017-28 (2008). WB ; Mouse . PubMed: 18354499
  • Subramanian K  et al. Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase. Mol Cell 30:336-47 (2008). WB ; Human . PubMed: 18471979
  • Fouladkou F  et al. The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization. Proc Natl Acad Sci U S A 105:8585-90 (2008). WB ; Mouse . PubMed: 18562292
  • Peters AL  et al. A novel polymorphism of the human CD40 receptor with enhanced function. Blood : (2008). PubMed: 18591382
  • Roussa E  et al. Transforming growth factor beta cooperates with persephin for dopaminergic phenotype induction. Stem Cells 26:1683-94 (2008). WB . PubMed: 18420832
  • Herrera RA  et al. Disruption of IFN-gamma- mediated antiviral activity in neurons: the role of cannabinoids. Viral Immunol 21:141-52 (2008). WB ; Human . PubMed: 18570588
  • Liovic M  et al. Dual-specificity phosphatases in the hypo-osmotic stress response of keratin-defective epithelial cell lines. Exp Cell Res 314:2066-75 (2008). WB . PubMed: 18410923
  • Campanella M  et al. Regulation of mitochondrial structure and function by the F1Fo-ATPase inhibitor protein, IF1. Cell Metab 8:13-25 (2008). WB ; Human . PubMed: 18590689
  • Denk GU  et al. Role of mitogen-activated protein kinases in tauroursodeoxycholic acid-induced bile formation in cholestatic rat liver. Hepatol Res 38:717-26 (2008). WB ; Rat . PubMed: 18328068
  • Ohse T  et al. Establishment of Conditionally Immortalized Mouse Glomerular Parietal Epithelial Cells in Culture. J Am Soc Nephrol : (2008). PubMed: 18596122
  • Shimano M  et al. Pioglitazone, a peroxisome proliferator-activated receptor-gamma activator, attenuates atrial fibrosis and atrial fibrillation promotion in rabbits with congestive heart failure. Heart Rhythm 5:451-9 (2008). PubMed: 18313605
  • Kaku N  et al. Characterization of nuclear import of the domain-specific androgen receptor in association with the importin alpha/beta and Ran-guanosine 5'-triphosphate systems. Endocrinology 149:3960-9 (2008). PubMed: 18420738
  • Su SC  et al. Molecular profile of endothelial invasion of three-dimensional collagen matrices: insights into angiogenic sprout induction in wound healing. Am J Physiol Cell Physiol : (2008). PubMed: 18787072
  • Forafonov F  et al. p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity. Mol Cell Biol 28:3446-56 (2008). WB ; Mouse . PubMed: 18362168
  • Fetalvero KM  et al. Prostacyclin primes pregnant human myometrium for an enhanced contractile response in parturition. J Clin Invest 118:3966-79 (2008). WB ; Human . PubMed: 19033666
  • Leung EL  et al. Cisplatin alters nitric oxide synthase levels in human ovarian cancer cells: involvement in p53 regulation and cisplatin resistance. Br J Cancer 98:1803-9 (2008). WB ; Human . PubMed: 18506185
  • Sasaki T  et al. Phosphorylation regulates SIRT1 function. PLoS ONE 3:e4020 (2008). WB . PubMed: 19107194
  • Larabee JL  et al. Bacillus anthracis edema toxin activates nuclear glycogen synthase kinase 3beta. Infect Immun 76:4895-904 (2008). PubMed: 18765729
  • Kishikawa M  et al. aPKC enables development of zonula adherens by antagonizing centripetal contraction of the circumferential actomyosin cables. J Cell Sci 121:2481-92 (2008). PubMed: 18628308
  • Jorgensen E  et al. Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells. BMC Cancer 8:229 (2008). WB . PubMed: 18694499
  • Abedini MR  et al. Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells. Cancer Res 68:4511-7 (2008). PubMed: 18559494
  • Fraser M  et al. Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function. Int J Cancer 122:534-46 (2008). PubMed: 17918180
  • Chen J  et al. Interaction of glyceraldehyde-3-phosphate dehydrogenase in the light-induced rod alpha-transducin translocation. J Neurochem 104:1280-92 (2008). PubMed: 18028335
  • Margineantu DH  et al. Hsp90 inhibition decreases mitochondrial protein turnover. PLoS One 2:e1066 (2007). PubMed: 17957250
  • Gould TD  et al. Beta-catenin overexpression in the mouse brain phenocopies lithium-sensitive behaviors. Neuropsychopharmacology 32:2173-83 (2007). PubMed: 17299510
  • Said HM  et al. GAPDH is not regulated in human glioblastoma under hypoxic conditions. BMC Mol Biol 8:55 (2007). WB ; Human . PubMed: 17597534
  • García-San Frutos M  et al. Impaired central insulin response in aged Wistar rats: role of adiposity. Endocrinology 148:5238-47 (2007). WB ; Rat . PubMed: 17673515
  • Thakurdas SM  et al. The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections. J Biol Chem 282:20809-15 (2007). WB ; Mouse . PubMed: 17456473
  • Sartório CL  et al. Mineralocorticoid receptor blockade improves vasomotor dysfunction and vascular oxidative stress early after myocardial infarction. Hypertension 50:919-25 (2007). PubMed: 17846350
  • Smith P  et al. Epigenetic inactivation implies independent functions for insulin-like growth factor binding protein (IGFBP)-related protein 1 and the related IGFBPL1 in inhibiting breast cancer phenotypes. Clin Cancer Res 13:4061-8 (2007). PubMed: 17634530
  • Xue C  et al. p53 determines multidrug sensitivity of childhood neuroblastoma. Cancer Res 67:10351-60 (2007). PubMed: 17974978
  • López-Ríos F  et al. Loss of the mitochondrial bioenergetic capacity underlies the glucose avidity of carcinomas. Cancer Res 67:9013-7 (2007). PubMed: 17909002
  • Townsend PA  et al. Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress. Am J Physiol Heart Circ Physiol 293:H928-38 (2007). PubMed: 17483234
  • Trebec DP  et al. Increased expression of activating factors in large osteoclasts could explain their excessive activity in osteolytic diseases. J Cell Biochem 101:205-20 (2007). PubMed: 17216600
  • Fritsche E  et al. Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation. Proc Natl Acad Sci U S A 104:8851-6 (2007). PubMed: 17502624
  • Cox ML  et al. The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor. Eur J Pharmacol 570:50-6 (2007). PubMed: 17588560
  • Kaimori A  et al. Transforming growth factor-beta1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro. J Biol Chem 282:22089-101 (2007). WB ; Mouse . PubMed: 17513865
  • Welch EM  et al. PTC124 targets genetic disorders caused by nonsense mutations. Nature 447:87-91 (2007). PubMed: 17450125
  • Dikovskaya D  et al. Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis. J Cell Biol 176:183-95 (2007). PubMed: 17227893
  • Harrison SM  et al. Lithium chloride inhibits the coronavirus infectious bronchitis virus in cell culture. Avian Pathol 36:109-14 (2007). PubMed: 17479370
  • Smeyne M  et al. GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism. Proc Natl Acad Sci U S A 104:1977-82 (2007). WB ; Mouse . PubMed: 17267597
  • Abend JR  et al. Inhibitory effect of gamma interferon on BK virus gene expression and replication. J Virol 81:272-9 (2007). WB ; Human . PubMed: 17035315
  • Sandig H  et al. Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone. Proc Natl Acad Sci U S A 104:12440-4 (2007). WB ; Human . PubMed: 17640905
  • Rolfe KJ  et al. A role for TGF-beta1-induced cellular responses during wound healing of the non-scarring early human fetus? J Invest Dermatol 127:2656-67 (2007). PubMed: 17687390
  • Szatmari I  et al. PPARgamma regulates the function of human dendritic cells primarily by altering lipid metabolism. Blood 110:3271-80 (2007). PubMed: 17664351
  • Kuhl AJ  et al. CCAAT/enhancer binding protein beta, but not steroidogenic factor-1, modulates the phthalate-induced dysregulation of rat fetal testicular steroidogenesis. Endocrinology 148:5851-64 (2007). PubMed: 17884934
  • Tompkins VS  et al. A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability. J Biol Chem 282:1322-33 (2007). WB ; Human . PubMed: 17110379
  • Doble BW  et al. Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines. Dev Cell 12:957-71 (2007). PubMed: 17543867
  • Xie P  et al. Cooperation between TNF receptor-associated factors 1 and 2 in CD40 signaling. J Immunol 176:5388-400 (2006). WB ; Mouse . PubMed: 16622006
  • Wu D  et al. A growth-maturation system that enhances the meiotic and developmental competence of porcine oocytes isolated from small follicles. Biol Reprod 75:547-54 (2006). WB ; Pig . PubMed: 16807383
  • Bilodeau S  et al. Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease. Genes Dev 20:2871-86 (2006). PubMed: 17043312
  • Fassett J  et al. Type I collagen structure regulates cell morphology and EGF signaling in primary rat hepatocytes through cAMP-dependent protein kinase A. Mol Biol Cell 17:345-56 (2006). PubMed: 16251347
  • Conway JP & Kinter M Dual role of peroxiredoxin I in macrophage-derived foam cells. J Biol Chem 281:27991-8001 (2006). PubMed: 16880205
  • Rohrbach S  et al. The thioredoxin system in aging muscle: key role of mitochondrial thioredoxin reductase in the protective effects of caloric restriction? Am J Physiol Regul Integr Comp Physiol 291:R927-35 (2006). PubMed: 16675629
  • Okkenhaug K  et al. The p110delta isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells. J Immunol 177:5122-8 (2006). PubMed: 17015696
  • Xia XG  et al. Pol II-expressed shRNA knocks down Sod2 gene expression and causes phenotypes of the gene knockout in mice. PLoS Genet 2:e10 (2006). PubMed: 16450009
  • Johnson BM  et al. Characterization of transport protein expression in multidrug resistance-associated protein (mrp) 2-deficient rats. Drug Metab Dispos 34:556-62 (2006). PubMed: 16204465
  • Fediuc S  et al. Effect of voluntary wheel running on circadian corticosterone release and on HPA axis responsiveness to restraint stress in Sprague-Dawley rats. J Appl Physiol 100:1867-75 (2006). PubMed: 16439512
  • Sharghi-Namini S  et al. The structural and functional integrity of peripheral nerves depends on the glial-derived signal desert hedgehog. J Neurosci 26:6364-76 (2006). PubMed: 16763045
  • Dove BK  et al. Changes in nucleolar morphology and proteins during infection with the coronavirus infectious bronchitis virus. Cell Microbiol 8:1147-57 (2006). PubMed: 16819967
  • Fan J  et al. En masse nascent transcription analysis to elucidate regulatory transcription factors. Nucleic Acids Res 34:1492-500 (2006). PubMed: 16540593
  • Szatmari I  et al. Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells. J Biol Chem 281:23812-23 (2006). PubMed: 16785230
  • Bashamboo A  et al. The survival of differentiating embryonic stem cells is dependent on the SCF-KIT pathway. J Cell Sci 119:3039-46 (2006). PubMed: 16820414
  • Karakas B  et al. Interleukin-1 alpha mediates the growth proliferative effects of transforming growth factor-beta in p21 null MCF-10A human mammary epithelial cells. Oncogene 25:5561-9 (2006). PubMed: 16619041
  • Bentham M  et al. Role of myristoylation and N-terminal basic residues in membrane association of the human immunodeficiency virus type 1 Nef protein. J Gen Virol 87:563-71 (2006). PubMed: 16476977
  • Lee DC  et al. Enhanced cystatin C and lysosomal protease expression following 6-hydroxydopamine exposure. Neurotoxicology 27:260-76 (2006). PubMed: 16414118
  • Rouleau C  et al. Protein tyrosine phosphatase PRL-3 in malignant cells and endothelial cells: expression and function. Mol Cancer Ther 5:219-29 (2006). PubMed: 16505094
  • Dove B  et al. Cell cycle perturbations induced by infection with the coronavirus infectious bronchitis virus and their effect on virus replication. J Virol 80:4147-56 (2006). PubMed: 16571830
  • Fraser M  et al. Regulation of p53 and suppression of apoptosis by the soluble guanylyl cyclase/cGMP pathway in human ovarian cancer cells. Oncogene 25:2203-12 (2006). PubMed: 16288207
  • Carroll RC  et al. Prospective evaluation of platelet B2 bradykinin and thrombopoietin receptor levels from preeclamptic compared to non-preeclamptic pregnancy patients. Thromb Res 117:551-6 (2006). PubMed: 15978658
  • Schonhoff CM  et al. S-nitrosothiol depletion in amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 103:2404-9 (2006). WB ; Mouse, Rat . PubMed: 16461917
  • Szatmari I  et al. PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells. J Exp Med 203:2351-62 (2006). WB . PubMed: 16982809
  • Bauersachs J  et al. Simvastatin improves left ventricular function after myocardial infarction in hypercholesterolemic rabbits by anti-inflammatory effects. Cardiovasc Res 72:438-46 (2006). PubMed: 17026973
  • Longworth MS  et al. HPV31 E7 facilitates replication by activating E2F2 transcription through its interaction with HDACs. EMBO J 24:1821-30 (2005). PubMed: 15861133
  • Homer HA  et al. RNA interference in meiosis I human oocytes: towards an understanding of human aneuploidy. Mol Hum Reprod 11:397-404 (2005). WB ; Human, Mouse . PubMed: 15908454
  • Bouzeghrane F  et al. Enhanced expression of fibrillin-1, a constituent of the myocardial extracellular matrix in fibrosis. Am J Physiol Heart Circ Physiol 289:H982-91 (2005). WB ; Rat . PubMed: 15849235
  • D'Souza T  et al. Phosphorylation of claudin-3 at threonine 192 by cAMP-dependent protein kinase regulates tight junction barrier function in ovarian cancer cells. J Biol Chem 280:26233-40 (2005). PubMed: 15905176
  • Homer HA  et al. Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes. Reproduction 130:829-43 (2005). PubMed: 16322543
  • Schleicher M  et al. Cell cycle-regulated inactivation of endothelial NO synthase through NOSIP-dependent targeting to the cytoskeleton. Mol Cell Biol 25:8251-8 (2005). PubMed: 16135813
  • Park JY  et al. Chlorella dichloromethane extract ameliorates NO production and iNOS expression through the down-regulation of NF kappa B activity mediated by suppressed oxidative stress in RAW 264.7 macrophages. Clin Chim Acta 351:185-96 (2005). PubMed: 15563889
  • Cannon JD  et al. Proliferation of rat granulosa cells during the periovulatory interval. Endocrinology 146:414-22 (2005). PubMed: 15375025
  • Choudhary A  et al. Suppression of thrombospondin 1 and 2 production by herpes simplex virus 1 infection in cultured keratocytes. Mol Vis 11:163-8 (2005). PubMed: 15761388
  • Zhou H  et al. An RNA polymerase II construct synthesizes short-hairpin RNA with a quantitative indicator and mediates highly efficient RNAi. Nucleic Acids Res 33:e62 (2005). PubMed: 15805121
  • Fueger PT  et al. Hexokinase II protein content is a determinant of exercise endurance capacity in the mouse. J Physiol 566:533-41 (2005). PubMed: 15878951
  • Don S  et al. Neuronal-associated microtubule proteins class III beta-tubulin and MAP2c in neuroblastoma: role in resistance to microtubule-targeted drugs. Mol Cancer Ther 3:1137-46 (2004). PubMed: 15367708
  • Baskurt OK  et al. Modulation of endothelial nitric oxide synthase expression by red blood cell aggregation. Am J Physiol Heart Circ Physiol 286:H222-9 (2004). PubMed: 14512280
  • Cuezva JM  et al. The bioenergetic signature of lung adenocarcinomas is a molecular marker of cancer diagnosis and prognosis. Carcinogenesis 25:1157-63 (2004). PubMed: 14963017
  • Abedini MR  et al. Possible role of FLICE-like inhibitory protein (FLIP) in chemoresistant ovarian cancer cells in vitro. Oncogene 23:6997-7004 (2004). PubMed: 15258564
  • Griffin SV  et al. Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology. Am J Pathol 165:1175-85 (2004). PubMed: 15466384
  • Zaidi NF  et al. Intracellular calcium modulates the nuclear translocation of calsenilin. J Neurochem 89:593-601 (2004). PubMed: 15086516
  • Low J  et al. BKV and SV40 infection of human kidney tubular epithelial cells in vitro. Virology 323:182-8 (2004). PubMed: 15193914
  • Fassett JT  et al. The role of collagen structure in mitogen stimulation of ERK, cyclin D1 expression, and G1-S progression in rat hepatocytes. J Biol Chem 278:31691-700 (2003). PubMed: 12794085
  • Sumner CJ  et al. Valproic acid increases SMN levels in spinal muscular atrophy patient cells. Ann Neurol 54:647-54 (2003). PubMed: 14595654
  • Gilbert J & Man HY The X-Linked Autism Protein KIAA2022/KIDLIA Regulates Neurite Outgrowth via N-Cadherin and d-Catenin Signaling. eNeuro 3:N/A (0). PubMed: 27822498
  • Hollis F  et al. Involvement of CRFR1 in the Basolateral Amygdala in the Immediate Fear Extinction Deficit. eNeuro 3:N/A (0). PubMed: 27844053
  • DaSilva LL  et al. Activity-Regulated Cytoskeleton-Associated Protein Controls AMPAR Endocytosis through a Direct Interaction with Clathrin-Adaptor Protein 2. eNeuro 3:N/A (0). PubMed: 27257628
  • Isidor MS  et al. An siRNA-based method for efficient silencing of gene expression in mature brown adipocytes. Adipocyte 5:175-85 (0). WB . PubMed: 27386153

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