Overview

  • Product name

  • Description

    Rabbit polyclonal to GAS41
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Chicken, Cow, Xenopus laevis, Zebrafish
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-163 of Human GAS41

  • Positive control

    • A549 whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab127198 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 27 kDa.

Target

  • Function

    Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
  • Tissue specificity

    Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
  • Sequence similarities

    Contains 1 YEATS domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • 4930573H17Rik antibody
    • B230215M10Rik antibody
    • GAS 41 antibody
    • Gas41 antibody
    • glioma amplified sequence 41 antibody
    • Glioma-amplified sequence 41 antibody
    • glioma-amplified sequence-41 antibody
    • gliomaamplified sequence 41 antibody
    • gliomaamplified sequence41 antibody
    • NUBI 1 antibody
    • NuBI-1 antibody
    • NuBI1 antibody
    • NuMA binding protein 1 antibody
    • NuMA-binding protein 1 antibody
    • YAF9 antibody
    • YEATS domain containing 4 antibody
    • YEATS domain containing4 antibody
    • YEATS domain-containing protein 4 antibody
    • YEATS4 antibody
    • YETS4_HUMAN antibody
    see all

Images

  • Anti-GAS41 antibody (ab127198) at 1/1000 dilution + A549 whole cell lysate at 30 µg

    Predicted band size: 27 kDa



    12% SDS-PAGE

References

ab127198 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab127198.
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