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    gastrin-antibody-prediluted-ab928.pdf

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Anti-Gastrin antibody, prediluted (ab928)

  • Datasheet
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Key features and details

  • Rabbit polyclonal to Gastrin, prediluted
  • Reacts with: Human
  • Isotype: IgG

You may also be interested in

Protein
Product image
Recombinant Human Gastrin protein (ab131754)
Secondary
Product image
Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

View more associated products

Overview

  • Product name

    Anti-Gastrin antibody, prediluted
    See all Gastrin primary antibodies
  • Description

    Rabbit polyclonal to Gastrin, prediluted
  • Host species

    Rabbit
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein conjugated to KLH.

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C. Do Not Freeze.
  • Storage buffer

    Preservative: 0.05% Sodium azide

    Inert stabilizer
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Polyclonal
  • Myeloma

    unknown
  • Isotype

    IgG
  • Research areas

    • Cardiovascular
    • Blood
    • Other
    • Signal Transduction
    • Growth Factors/Hormones
    • Hormones
    • Cancer
    • Tumor biomarkers
    • Hormones
    • Cardiovascular
    • Atherosclerosis
    • Vascular Inflammation
    • Leukocyte recruitment
    • Other

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human Gastrin protein (ab131754)

Applications

  • Application notes
    This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections.
    No further titration is required.
    We suggest an incubation period of 30-60 minutes at room temperature.
    However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user.
  • Target

    • Function

      Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
    • Sequence similarities

      Belongs to the gastrin/cholecystokinin family.
    • Post-translational
      modifications

      Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71.
      Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P01350 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 2520 Human
      • Omim: 137250 Human
      • SwissProt: P01350 Human
      • Unigene: 2681 Human
      • Alternative names

        • Component II antibody
        • G14 antibody
        • G17 antibody
        • G34 antibody
        • G52 antibody
        • G6 antibody
        • GAS antibody
        • Gast antibody
        • GAST_HUMAN antibody
        • Gastrin antibody
        • Gastrin component I antibody
        • Gastrin component II antibody
        • Gastrin component III antibody
        • Gastrin precursor antibody
        • Gastrin-14 antibody
        • Gastrin-17 antibody
        • Gastrin-34 antibody
        • Gastrin-52 antibody
        • Gastrin-6 antibody
        • Gastrin-71 antibody
        see all

      Protocols

      • Immunohistochemistry protocols

      Click here to view the general protocols

      Datasheets and documents

      • Datasheet
    • References (0)

      Publishing research using ab928? Please let us know so that we can cite the reference in this datasheet.

      ab928 has not yet been referenced specifically in any publications.

      Customer reviews and Q&As

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