Overview

  • Product name

    Anti-GATA3 antibody [KT77]
    See all GATA3 primary antibodies
  • Description

    Rat monoclonal [KT77] to GATA3
  • Host species

    Rat
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    Full length protein (Mouse)

Properties

Applications

Our Abpromise guarantee covers the use of ab110093 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 1 µg/ml. Predicted molecular weight: 48 kDa.
ICC/IF Use a concentration of 1 - 10 µg/ml.

Target

  • Function

    Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.
  • Tissue specificity

    T-cells and endothelial cells.
  • Involvement in disease

    Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome.
  • Sequence similarities

    Contains 2 GATA-type zinc fingers.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Form

    There are 2 isoforms produced by alternative splicing.
  • Alternative names

    • GATA 3 antibody
    • GATA binding factor 3 antibody
    • GATA binding protein 3 antibody
    • GATA-binding factor 3 antibody
    • Gata3 antibody
    • GATA3_HUMAN antibody
    • HDR antibody
    • HDRS antibody
    • MGC2346 antibody
    • MGC5199 antibody
    • MGC5445 antibody
    • Trans acting T cell specific transcription factor GATA 3 antibody
    • Trans-acting T-cell-specific transcription factor GATA-3 antibody
    see all

References

This product has been referenced in:

  • Newland SA  et al. Type-2 innate lymphoid cells control the development of atherosclerosis in mice. Nat Commun 8:15781 (2017). IHC-Fr ; Mouse . Read more (PubMed: 28589929) »
See 1 Publication for this product

Customer reviews and Q&As

Answer

Thank you for contacting us. I have checked our catalog and found 4 anti-GATA3 antibodies that have been tested in mouse (ab32858, ab106625, ab82828 and ab110093), however none of these antibodies has been tested so far in frozen tissue sections (IHC-Fr). ab32858 and ab106625 were tested so far in IHC-P (paraffin sections) and WB. ab82828 has been tested in ELISA and WB ab110093 has been tested in ICC/IF and WB Any of the IHC-P or ICC/IF tested antibodies are worthwile to try with frozen sections. For UNTESTED species and/or applications, we have established a testing discount program. Here is a brief description of how it works: The testing discount program is for customers who like to use an antibody/protein on an untested species/application. You would purchase the antibody at full price, test it and submit an Abreview with your data (positive or negative). On your next order you will receive a discount for ONE antibody at the full price (100%) of the antibody you have tested. The terms and conditions applicable to this offer can be found here: www.abcam.com/collaborationdiscount. Please let me know if I shall send you a discount code for trying out one of these antibodies. I look forward to hear back from you and assist you further.

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