Overview

  • Product name

    Gatifloxacin, Fluoroquinolone antibiotic
  • Description

    Fluoroquinolone antibiotic
  • Alternative names

    • AM1155
  • Biological description

    Fluoroquinolone antibiotic. Inhibits bacterial DNA gyrase and type II topoisomerase (IC50 values are 0.109 and 13.8 µg/ml respectively. Pharmacologically active following oral administration. Crosses the blood-brain barrier.
  • Purity

    > 98%
  • CAS Number

    112811-59-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Devada SS  et al. Pharmacokinetics of gatifloxacin in broiler chickens following intravenous and oral administration. Br Poult Sci 53:257-61 (2012). Read more (PubMed: 22646791) »
  • Li Y  et al. Transport of gatifloxacin involves Na+/Ca2+ exchange and excludes P-glycoprotein and multidrug resistance associated-proteins in primary cultured rat brain endothelial cells. Eur J Pharmacol 616:68-72 (2009). Read more (PubMed: 19497321) »
  • Drlica K Mechanism of fluoroquinolone action. Curr Opin Microbiol 2:504-8 (1999). Read more (PubMed: 10508721) »

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