Anti-GBA2 antibody (ab69366)
Key features and details
- Mouse polyclonal to GBA2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GBA2 antibody
See all GBA2 primary antibodies -
Description
Mouse polyclonal to GBA2 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein within Human GBA2. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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Positive control
- GBA2 transfected 293T lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab69366 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Detects a band of approximately 105 kDa (predicted molecular weight: 105 kDa).
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Notes |
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WB
1/500 - 1/1000. Detects a band of approximately 105 kDa (predicted molecular weight: 105 kDa). |
Target
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Relevance
GBA2 is a non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide. It is involved in sphingomyelin generation and prevention of glycolipid accumulation. GBA2 may also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. -
Cellular localization
Cell membrane; Single-pass membrane protein. Note=Not localized to lipid rafts. -
Database links
- Entrez Gene: 57704 Human
- GenBank: NM_020944.2 Human
- Omim: 609471 Human
- SwissProt: Q9HCG7 Human
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Alternative names
- AD035 antibody
- Beta glucocerebrosidase 2 antibody
- Beta glucosidase 2 antibody
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Images
Datasheets and documents
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Datasheet download
References (0)
ab69366 has not yet been referenced specifically in any publications.