Overview

  • Product name
    Anti-GCHFR antibody
    See all GCHFR primary antibodies
  • Description
    Rabbit polyclonal to GCHFR
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide derived from an internal sequence of Human GCHFR.

  • Positive control
    • Human colon carcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab110161 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.
  • Tissue specificity
    In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level).
  • Sequence similarities
    Belongs to the GFRP family.
  • Cellular localization
    Nucleus. Nucleus membrane. Cytoplasm > cytosol.
  • Information by UniProt
  • Database links
    • Alternative names
      • GCHFR antibody
      • GFRP antibody
      • GFRP_HUMAN antibody
      • GTP cyclohydrolase 1 feedback regulatory protein antibody
      • GTP cyclohydrolase I feedback regulator antibody
      • GTP cyclohydrolase I feedback regulatory protein antibody
      • HsT16933 antibody
      • MGC138467 antibody
      • MGC138469 antibody
      • p35 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GCHFR antibody (ab110161)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GCHFR antibody (ab110161)
      ab110161, at a 1/50 dilution, staining GCHFR in paraffin embedded Human colon carcinoma tissue by Immunohistochemistry, in the presence (right panel) or absence (left panel) of the immunizing peptide.

    References

    ab110161 has not yet been referenced specifically in any publications.

    Publishing research using ab110161? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

    Submit a review Submit a question

    1 Review or Q&A

    10
    Votes: Highest First

    send info about testing discount program

    Thank you very much for your interest in ab110161.
    To our knowledge, ab110161 has not been tested in IP. Therefore, I can offer a discount off a future purchase if you buy ab110161 now, test it in IP and submit feedback to us in the form of an Abr...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up