Anti-GCHFR antibody (ab110161)

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Overview

  • Product name

    Anti-GCHFR antibody
    See all GCHFR primary antibodies

  • Description

    Rabbit polyclonal to GCHFR

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rat

  • Immunogen

    Synthetic peptide derived from an internal sequence of Human GCHFR.

  • Positive control

    • Human colon carcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab110161 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.

  • Tissue specificity

    In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level).

  • Sequence similarities

    Belongs to the GFRP family.

  • Cellular localization

    Nucleus. Nucleus membrane. Cytoplasm > cytosol.
  • Information by UniProt

  • Database links

    • Alternative names

      • GCHFR antibody
      • GFRP antibody
      • GFRP_HUMAN antibody
      • GTP cyclohydrolase 1 feedback regulatory protein antibody
      • GTP cyclohydrolase I feedback regulator antibody
      • GTP cyclohydrolase I feedback regulatory protein antibody
      • HsT16933 antibody
      • MGC138467 antibody
      • MGC138469 antibody
      • p35 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GCHFR antibody (ab110161)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GCHFR antibody (ab110161)
      ab110161, at a 1/50 dilution, staining GCHFR in paraffin embedded Human colon carcinoma tissue by Immunohistochemistry, in the presence (right panel) or absence (left panel) of the immunizing peptide.

    References

    ab110161 has not yet been referenced specifically in any publications.

    Publishing research using ab110161? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

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    Question

    send info about testing discount program

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    Answer

    Thank you very much for your interest in ab110161.
    To our knowledge, ab110161 has not been tested in IP. Therefore, I can offer a discount off a future purchase if you buy ab110161 now, test it in IP and submit feedback to us in the form of an Abreview. It doesn’t matter whether the Abreview is positive or negative, we would just really like to receive your feedback. The discount would be to the value of: 1 free PRIMARY ANTIBODY.
    If you are interested in this offer, please follow these steps:
    1. Reply to this e-mail to let me know that you would like to proceed and test ab110161 in IP. I will then send a discount code. This code must be issued before purchasing ab110161 so please wait for my reply before ordering.
    2. Purchase ab110161 either by phone, fax, or online (www.abcam.com).
    3. Test it in IP.
    4. Let us know the results, positive or negative, using our Abreview system (this will take about 10 minutes and images are great if you have them!). To find out how to submit an Abreview, please visit: https://www.abcam.com/abreviews.
    5. After the review is submitted to us, the discount code becomes active. Simply place your new order by phone, fax, or on the web and mention the discount code. The discount can be redeemed for any PRIMARY ANTIBODY ordered and the discount code is valid for 4 months after issue.
    Please remember that submission of the Abreview is sufficient for the discount code to become active.
    We are always pleased to obtain feedback about our products and any information is greatly appreciated! Even if ab110161 turns out to be unsuitable for IP, you will still receive the discount on your next purchase after your Abreview has been submitted.
    Please let me know if you have any questions about this offer and I would be happy to help you further.
    The Terms and Conditions of this offer can be found at: www.abcam.com/collaborationdiscount.

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