Anti-GCHFR antibody (ab110161)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GCHFR antibody (ab110161)

    Key features and details

    • Rabbit polyclonal to GCHFR
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

    Overview

    • Product name

      Anti-GCHFR antibody
      See all GCHFR primary antibodies

    • Description

      Rabbit polyclonal to GCHFR

    • Host species

      Rabbit

    • Tested applications

      Suitable for: IHC-Pmore details

    • Species reactivity

      Reacts with: Human
      Predicted to work with: Rat

    • Immunogen

      Synthetic peptide derived from an internal sequence of Human GCHFR.

    • Positive control

      • Human colon carcinoma tissue

    • General notes

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    Applications

    Our Abpromise guarantee covers the use of ab110161 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

    Target

    • Function

      Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.

    • Tissue specificity

      In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level).

    • Sequence similarities

      Belongs to the GFRP family.

    • Cellular localization

      Nucleus. Nucleus membrane. Cytoplasm > cytosol.
    • Information by UniProt

    • Database links

      • Alternative names

        • GCHFR antibody
        • GFRP antibody
        • GFRP_HUMAN antibody
        • GTP cyclohydrolase 1 feedback regulatory protein antibody
        • GTP cyclohydrolase I feedback regulator antibody
        • GTP cyclohydrolase I feedback regulatory protein antibody
        • HsT16933 antibody
        • MGC138467 antibody
        • MGC138469 antibody
        • p35 antibody
        see all

      Images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GCHFR antibody (ab110161)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GCHFR antibody (ab110161)
        ab110161, at a 1/50 dilution, staining GCHFR in paraffin embedded Human colon carcinoma tissue by Immunohistochemistry, in the presence (right panel) or absence (left panel) of the immunizing peptide.

      References (0)

      Publishing research using ab110161? Please let us know so that we can cite the reference in this datasheet.

      ab110161 has not yet been referenced specifically in any publications.

      Customer reviews and Q&As

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      Question

      send info about testing discount program

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      Answer

      Thank you very much for your interest in ab110161.
      To our knowledge, ab110161 has not been tested in IP. Therefore, I can offer a discount off a future purchase if you buy ab110161 now, test it in IP and submit feedback to us in the form of an Abreview. It doesn’t matter whether the Abreview is positive or negative, we would just really like to receive your feedback. The discount would be to the value of: 1 free PRIMARY ANTIBODY.
      If you are interested in this offer, please follow these steps:
      1. Reply to this e-mail to let me know that you would like to proceed and test ab110161 in IP. I will then send a discount code. This code must be issued before purchasing ab110161 so please wait for my reply before ordering.
      2. Purchase ab110161 either by phone, fax, or online (www.abcam.com).
      3. Test it in IP.
      4. Let us know the results, positive or negative, using our Abreview system (this will take about 10 minutes and images are great if you have them!). To find out how to submit an Abreview, please visit: https://www.abcam.com/abreviews.
      5. After the review is submitted to us, the discount code becomes active. Simply place your new order by phone, fax, or on the web and mention the discount code. The discount can be redeemed for any PRIMARY ANTIBODY ordered and the discount code is valid for 4 months after issue.
      Please remember that submission of the Abreview is sufficient for the discount code to become active.
      We are always pleased to obtain feedback about our products and any information is greatly appreciated! Even if ab110161 turns out to be unsuitable for IP, you will still receive the discount on your next purchase after your Abreview has been submitted.
      Please let me know if you have any questions about this offer and I would be happy to help you further.
      The Terms and Conditions of this offer can be found at: www.abcam.com/collaborationdiscount.

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      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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