Anti-GCM1 antibody - C-terminal (ab187860)
Key features and details
- Rabbit polyclonal to GCM1 - C-terminal
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GCM1 antibody - C-terminal
See all GCM1 primary antibodies -
Description
Rabbit polyclonal to GCM1 - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human GCM1 aa 300 to the C-terminus (C terminal).
Database link: Q9NP62 -
Positive control
- ICC/IF: U-2 OS whole cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab187860 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF | (1) |
Use a concentration of 0.25 - 2 µg/ml.
Fixation/Permeabilization: PFA/Triton X-100 |
Notes |
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ICC/IF
Use a concentration of 0.25 - 2 µg/ml. Fixation/Permeabilization: PFA/Triton X-100 |
Target
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Function
Transcription factor that is necessary for placental development. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. -
Tissue specificity
Placenta specific. -
Sequence similarities
Contains 1 GCM DNA-binding domain. -
Post-translational
modificationsPolyubiquitinated in the presence of UBE2D2 and FBXW2 (in vitro). -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 8521 Human
- Omim: 603715 Human
- SwissProt: Q9NP62 Human
- Unigene: 28346 Human
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Alternative names
- Chorion specific transcription factor GCMa antibody
- Chorion-specific transcription factor GCMa antibody
- GCM 1 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab187860 has been referenced in 2 publications.
- Zhao L et al. In vitro fertilization and embryo transfer alter human placental function through trophoblasts in early pregnancy. Mol Med Rep 21:1897-1909 (2020). PubMed: 32319609
- Zhao L et al. The placental transcriptome of the first-trimester placenta is affected by in vitro fertilization and embryo transfer. Reprod Biol Endocrinol 17:50 (2019). PubMed: 31262321