Anti-GCM2 antibody (ab201170)
Key features and details
- Rabbit polyclonal to GCM2
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GCM2 antibody
See all GCM2 primary antibodies -
Description
Rabbit polyclonal to GCM2 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Recombinant fragment corresponding to Human GCM2 aa 1-250.
Database link: O75603 -
Positive control
- A431 cell line lysate, human fetal brain tissue lysate and human fetal testis tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Lyophilized:Reconstitute in 200 uL sterile distilled water. -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab201170 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P | (1) |
1/100 - 1/500.
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WB |
1/200 - 1/1000. Predicted molecular weight: 57 kDa.
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Notes |
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IHC-P
1/100 - 1/500. |
WB
1/200 - 1/1000. Predicted molecular weight: 57 kDa. |
Target
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Relevance
Gcm2, a mouse ortholog of the Drosophila Glial Cells Missing gene, is expressed in the parathyroid-specific domains in the 3rd pouches from E9.5. The null mutation of Gcm2 causes aparathyroidism in the fetal and adult mouse and has been proposed to be a master regulator for parathyroid development. During Drosophila embryogenesis Gcm2 plays a crucial role in promoting glial cell differentiation. -
Cellular localization
Nuclear -
Database links
- Entrez Gene: 9247 Human
- Omim: 603716 Human
- SwissProt: O75603 Human
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Alternative names
- chorion specific transcription factor GCMb antibody
- Chorion-specific transcription factor GCMb antibody
- GCM motif protein 2 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab201170 has been referenced in 3 publications.
- Kelly YM et al. Effects of Multi-stage Procurement on the Viability and Function of Human Donor Parathyroid Glands. J Surg Res 276:404-415 (2022). PubMed: 35468367
- Koh J et al. Ex Vivo Intact Tissue Analysis Reveals Alternative Calcium-sensing Behaviors in Parathyroid Adenomas. J Clin Endocrinol Metab 106:3168-3183 (2021). PubMed: 34272844
- Kakuta T et al. Parathyroid hormone-producing cells exist in adipose tissues surrounding the parathyroid glands in hemodialysis patients with secondary hyperparathyroidism. Sci Rep 10:3290 (2020). PubMed: 32094398