Key features and details
- Mouse monoclonal [C4] to GDF11
- Suitable for: IHC-P, WB
- Reacts with: Rat, Human
- Isotype: IgG2a
Product nameAnti-GDF11 antibody [C4]
See all GDF11 primary antibodies
DescriptionMouse monoclonal [C4] to GDF11
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Rat, Human
Recombinant fragment corresponding to Human GDF11 aa 138-386. N-terminal His tag. Expressed in E. coli.
TTETVISMAQETDPAVQTDGSPLCCHFHFSPKVMFTKVLKAQLWVYLRPV PRPATVYLQILRLKPLTGEGTAGGGGGGRRHIRIRSLKIELHSRSGHWQS IDFKQVLHSWFRQPQSNWGIEINAFDPSGTDLAVTSLGPGAEGLHPFMEL RVLENTKRSRRNLGLDCDEHSSESRCCRYPLTVDFEAFGWDWIIAPKRYK ANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFN
Database link: O95390
- WB: Recombinant human GDF11 protein. Rat spinal cord lysate. IHC-P: Human colorectal cancer tissue.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityProtein A/G purified
Purification notesPurified from TCS.
Light chain typekappa
Our Abpromise guarantee covers the use of ab239515 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 - 30 µg/ml.|
|WB||Use a concentration of 0.5 - 5 µg/ml.|
FunctionSecreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.
Sequence similaritiesBelongs to the TGF-beta family.
- Information by UniProt
- BMP 11 antibody
- BMP-11 antibody
- BMP11 antibody
Paraffin-embedded human colorectal cancer tissue stained for GDF11 with ab239515 at 30 µg/ml in immunohistochemical analysis. DAB staining.
Anti-GDF11 antibody [C4] (ab239515) at 3 µg/ml + Rat spinal cord lysate
HRP-linked Goat Anti-Mouse IgG at 0.2 µg/ml
Anti-GDF11 antibody [C4] (ab239515) at 5 µg/ml + Recombinant human GDF11 protein
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab239515 has not yet been referenced specifically in any publications.