Anti-GDF15 antibody (ab105738)
Key features and details
- Rabbit polyclonal to GDF15
- Suitable for: WB
- Reacts with: Mouse, Recombinant fragment
- Isotype: IgG
Overview
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Product name
Anti-GDF15 antibody
See all GDF15 primary antibodies -
Description
Rabbit polyclonal to GDF15 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Recombinant fragment
Predicted to work with: Rat, Cow, Dog, Pig
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Immunogen
Synthetic peptide corresponding to amino acids near the C-terminal of Mouse GDF15.
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General notes
Expiration date is one (1) year from date of opening product.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 0.42% Potassium phosphate, 0.88% Sodium chloride -
Concentration information loading... -
Purity
Protein A purified -
Purification notes
ab105738 is affinity purified from monospecific antiserum by immunoaffinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab105738 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/3000 - 1/7000. Predicted molecular weight: 33 kDa.
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| Notes |
|---|
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WB
1/3000 - 1/7000. Predicted molecular weight: 33 kDa. |
Target
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Tissue specificity
Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney. -
Sequence similarities
Belongs to the TGF-beta family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 618677 Cow
- Entrez Gene: 23886 Mouse
- Entrez Gene: 29455 Rat
- SwissProt: Q9Z0J7 Mouse
- SwissProt: Q9Z0J6 Rat
- Unigene: 31325 Mouse
- Unigene: 44228 Rat
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Alternative names
- GDF 15 antibody
- GDF-15 antibody
- Gdf15 antibody
see all
Images
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Western blot - Anti-GDF15 antibody (ab105738)All lanes : Anti-GDF15 antibody (ab105738) at 1/1000 dilution
Lane 1 : Recombinant MBP-GDF15 fusion protein purified from E.coli
Lane 2 : Yeast cell lysate expressing SUMO-Mouse GDF15
Lane 3 : Human GDF15 monomer purified from CHO-K1 cells
Secondary
All lanes : Goat-anti-Rabbit HRP at 1/40000 dilution
Performed under reducing conditions.
Predicted band size: 33 kDa
Expect bands in Western blots of approximately 14 and 28 kDa in size corresponding to GDF15 monomer and dimer, respectively.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab105738 has been referenced in 1 publication.
- Weng JH et al. Colchicine acts selectively in the liver to induce hepatokines that inhibit myeloid cell activation. Nat Metab 3:513-522 (2021). PubMed: 33846641