RecombinantRabMAb

Recombinant Anti-GDF15 antibody [EPR6982(2)] (ab180929)

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Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)
  • Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)
  • Anti-GDF15 antibody [EPR6982(2)] (ab180929)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR6982(2)] to GDF15
  • Suitable for: WB
  • Reacts with: Human

Overview

  • Product name

    Anti-GDF15 antibody [EPR6982(2)]
    See all GDF15 primary antibodies

  • Description

    Rabbit monoclonal [EPR6982(2)] to GDF15

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    This information is proprietary to Abcam and/or its suppliers.

  • Positive control

    • LnCap and HepG2 cell lysates.

  • General notes

     

     

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

Properties

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab180929 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
1/1000 - 1/10000. Detects a band of approximately 35 kDa (predicted molecular weight: 34 kDa).
Notes
WB
1/1000 - 1/10000. Detects a band of approximately 35 kDa (predicted molecular weight: 34 kDa).

Target

  • Tissue specificity

    Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.

  • Sequence similarities

    Belongs to the TGF-beta family.

  • Cellular localization

    Secreted.
  • Information by UniProt

  • Database links

    • Alternative names

      • GDF 15 antibody
      • GDF-15 antibody
      • Gdf15 antibody
      • GDF15_HUMAN antibody
      • Growth differentiation factor 15 antibody
      • Growth/differentiation factor 15 antibody
      • Macrophage inhibitory cytokine 1 antibody
      • MIC 1 antibody
      • Mic-1 antibody
      • MIC1 antibody
      • NAG 1 antibody
      • NAG-1 antibody
      • NAG1 antibody
      • NRG 1 antibody
      • NRG-1 antibody
      • NRG1 antibody
      • NSAID (nonsteroidal anti inflammatory drug) activated protein 1 antibody
      • NSAID antibody
      • NSAID regulated protein 1 antibody
      • NSAID-activated gene 1 protein antibody
      • NSAID-regulated gene 1 protein antibody
      • PDF antibody
      • PLAB antibody
      • Placental bone morphogenetic protein antibody
      • Placental bone morphogenic protein antibody
      • Placental TGF beta antibody
      • Placental TGF-beta antibody
      • Prostate differentiation factor antibody
      • PTGF beta antibody
      • PTGFB antibody
      see all

    Images

    • Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)
      Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)
      Anti-GDF15 antibody [EPR6982(2)] (ab180929) at 1/1000 dilution + HepG2 cell lysate at 10 µg

      Secondary
      Goat Anti-Rabbit IgG, (H+L), Peroxidase Conjugate at 1/1000 dilution

      Predicted band size: 34 kDa

    • Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)
      Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)
      Anti-GDF15 antibody [EPR6982(2)] (ab180929) at 1/5000 dilution + LnCap cell lysate at 10 µg

      Secondary
      Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

      Predicted band size: 34 kDa

    • Anti-GDF15 antibody [EPR6982(2)] (ab180929)
      Anti-GDF15 antibody [EPR6982(2)] (ab180929)

    References (1)

    Publishing research using ab180929? Please let us know so that we can cite the reference in this datasheet.

    ab180929 has been referenced in 1 publication.

    • Zhao C  et al. C5a induces A549 cell proliferation of non-small cell lung cancer via GDF15 gene activation mediated by GCN5-dependent KLF5 acetylation. Oncogene 37:4821-4837 (2018). PubMed: 29773900

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