Recombinant Anti-GDF15 antibody [EPR6982(2)] (ab180929)
Overview
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Product name
Anti-GDF15 antibody [EPR6982(2)]
See all GDF15 primary antibodies -
Description
Rabbit monoclonal [EPR6982(2)] to GDF15 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human GDF15 aa 250 to the C-terminus. The exact sequence is proprietary.
Database link: Q99988 -
Positive control
- LnCap and HepG2 cell lysates.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol, 0.05% BSA -
Concentration information loading... -
Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR6982(2) -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab180929 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000 - 1/10000. Detects a band of approximately 35 kDa (predicted molecular weight: 34 kDa). |
Target
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Tissue specificity
Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney. -
Sequence similarities
Belongs to the TGF-beta family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 9518 Human
- Omim: 605312 Human
- SwissProt: Q99988 Human
- Unigene: 616962 Human
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Alternative names
- GDF 15 antibody
- GDF-15 antibody
- Gdf15 antibody
see all
Images
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![Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)](https://www.abcam.com/ps/products/180/ab180929/Images/ab180929-214854-anti-gdf15-antibody-epr69822-western-blot.jpg)
Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)Anti-GDF15 antibody [EPR6982(2)] (ab180929) at 1/1000 dilution + HepG2 cell lysate at 10 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase Conjugate at 1/1000 dilution
Predicted band size: 34 kDa -
![Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)](https://www.abcam.com/ps/products/180/ab180929/Images/ab180929-214853-anti-gdf15-antibody-epr69822-western-blot.jpg)
Western blot - Anti-GDF15 antibody [EPR6982(2)] (ab180929)Anti-GDF15 antibody [EPR6982(2)] (ab180929) at 1/5000 dilution + LnCap cell lysate at 10 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution
Predicted band size: 34 kDa
Datasheets and documents
Certificate of Compliance
References
ab180929 has been referenced in 1 publication.
- Zhao C et al. C5a induces A549 cell proliferation of non-small cell lung cancer via GDF15 gene activation mediated by GCN5-dependent KLF5 acetylation. Oncogene 37:4821-4837 (2018). PubMed: 29773900
