Overview

  • Product name

  • Description

    Rabbit polyclonal to GDF6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Recombinant fragment within Human GDF6 (internal sequence). The exact sequence is proprietary.
    Database link: Q6KF10

  • Positive control

    • IHC-P: Rat brain tissue. WB: U-87 MG whole cell extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab226853 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 51 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Relevance

    GDF6 (Growth/differentiation factor 6) is expressed in hypertrophic chondrocytes during embryonic development of long bones and is required for normal formation of bones and joints in the limbs, skull, and axial skeleton. It plays a key role in establishing boundaries between skeletal elements during development. The functional form of GDF6 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains obtained by proteolytic processing of a biologically inactive precursor protein.
  • Cellular localization

    Secreted
  • Database links

  • Alternative names

    • bmp 13 antibody
    • bmp13 antibody
    • Cartilage Derived Morphogenetic Protein 2 antibody
    • cdmp 2 antibody
    • CDMP2 antibody
    • gdf 6 antibody
    • GDF16 antibody
    • Growth differentiation factor 6 antibody
    • Growth/differentiation factor 16 antibody
    • Growth/differentiation factor 6 antibody
    • KFM antibody
    • KFS antibody
    • KFS1 antibody
    • KFSL antibody
    • Klip Feil malformation antibody
    • Klippel Feil malformation antibody
    • Klippel Feil syndrome antibody
    • LCA17 antibody
    • MCOP4 antibody
    • MCOPCB6 antibody
    • SCDO4 antibody
    • SGM1 antibody
    see all

Images

  • Paraffin-embedded rat brain tissue stained for GDF6 using ab226853 at 1/500 dilution in immunohistochemical analysis.

  • Anti-GDF6 antibody (ab226853) at 1/2000 dilution + U-87 MG (human glioblastoma-astrocytoma epithelial cell line) whole cell extract at 30 µg

    Predicted band size: 51 kDa



    10% SDS-PAGE gel.

References

ab226853 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab226853.
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