Product nameAnti-GDNF Receptor alpha 1 antibody
See all GDNF Receptor alpha 1 primary antibodies
DescriptionRabbit polyclonal to GDNF Receptor alpha 1
Tested applicationsSuitable for: IHC (PFA fixed), IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide, corresponding to amino acids 369-382 of Human GFR alpha 1.
- Human brain lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of ab8026 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC (PFA fixed)|
Immunohistochemistry (PFA fixed): 1/50.
WB: 1/500. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionReceptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.
Sequence similaritiesBelongs to the GDNFR family.
Cellular localizationCell membrane.
- Information by UniProt
- GDNF family receptor alpha 1 antibody
- GDNF family receptor alpha-1 antibody
- GDNF R antibody
All lanes : Anti-GDNF Receptor alpha 1 antibody (ab8026) at 1/500 dilution
Lane 1 : Crude membrane fractions of human brain
Lane 2 : Crude membrane fractions of liver
Lane 3 : Crude membrane fractions of kidney
Lane 4 : Crude membrane fractions of spleen
Predicted band size: 50 kDa
Observed band size: 50 kDa
Western blot analysis of GFR alpha 1 in crude membrane fractions of human brain (B), liver (L), kidney (K), and spleen (S), respectively, with ab8026 at 1/500 dilution.
This product has been referenced in:
- Wang H et al. Transcriptional regulation of P63 on the apoptosis of male germ cells and three stages of spermatogenesis in mice. Cell Death Dis 9:76 (2018). Read more (PubMed: 29362488) »
- Fu H et al. PAK1 Promotes the Proliferation and Inhibits Apoptosis of Human Spermatogonial Stem Cells via PDK1/KDR/ZNF367 and ERK1/2 and AKT Pathways. Mol Ther Nucleic Acids 12:769-786 (2018). Read more (PubMed: 30141410) »