Key features and details
- Rabbit polyclonal to GDNF Receptor alpha 2/GFRA2
- Suitable for: IHC-P
- Reacts with: Rat, Human
- Isotype: IgG
Product nameAnti-GDNF Receptor alpha 2/GFRA2 antibody
See all GDNF Receptor alpha 2/GFRA2 primary antibodies
DescriptionRabbit polyclonal to GDNF Receptor alpha 2/GFRA2
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Rat, Human
Predicted to work with: Mouse
- Rat brain and Human placenta tissue.
This product was previously labelled as GDNF Receptor alpha 2
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 1% BSA, 50% Glycerol
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab216417 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.
When using a fluorescent probe the recommended dilution is 1/50 – 1/200.
FunctionReceptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
Isoform 2: Participates to NRTN-induced 'Ser-727' phosphorylation of STAT3.
Tissue specificityIsoform 1 is found in both brain and placenta.
Sequence similaritiesBelongs to the GDNFR family.
Cellular localizationCell membrane.
- Information by UniProt
- GDNF family receptor alpha 2 antibody
- GDNF family receptor alpha-2 antibody
- GDNF receptor alpha-2 antibody
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Rat brain labeling GDNF Receptor alpha 2/GFRA2 with ab216417 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human placenta tissue labeling GDNF Receptor alpha 2/GFRA2 with ab216417 at 1/200 dilution followed by Goat anti-rabbit IgG, PE conjugated, at 1/200 dilution for 40 minutes at 37°C
ab216417 has not yet been referenced specifically in any publications.