Overview

  • Product name

    Gemfibrozil, PPARalpha activator
  • Description

    PPARα activator
  • Biological description

    PPARα activator. Increases the expression of PPAR-β but not PPAR-γ. Shows lipid-lowering and anti-inflammatory effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    25812-30-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • El-Sisi A  et al. Effects of three different fibrates on intrahepatic cholestasis experimentally induced in rats. PPAR Res 2013:781348 (2013). Read more (PubMed: 23997763) »
  • Jana M  et al. Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-ß. J Biol Chem 287:34134-48 (2012). Read more (PubMed: 22879602) »
  • Skolness SY  et al. Effects of gemfibrozil on lipid metabolism, steroidogenesis, and reproduction in the fathead minnow (Pimephales promelas). Environ Toxicol Chem 31:2615-24 (2012). Read more (PubMed: 22911976) »

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