Overview

  • Product name

  • Description

    Rabbit polyclonal to Gemin 3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human Gemin 3 aa 25-280.
    Sequence:

    VQVPAP EPTPGPVRIL RTAQDLSSPR TRTGDVLLAE PADFESLLLS RPVLEGLRAA GFERPSPVQL KAIPLGRCGL DLIVQAKSGT GKTCVFSTIA LDSLVLENLS TQILILAPTR EIAVQIHSVI TAIGIKMEGL ECHVFIGGTP LSQDKTRLKK CHIAVGSPGR IKQLIELDYL NPGSIRLFIL DEADKLLEEG SFQEQINWIY SSLPASKQML AVSATYPEFL ANALTKYMRD PTFVRLNSSD PSLIGLKQYY


    Database link: Q9UHI6

  • Positive control

    • MCF7, ES-2, 293T, HepG2, HeLa, mouse spleen, mouse ovary, rat testis extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab189850 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 92 kDa.
IHC-P 1/50 - 1/200.

Target

  • Function

    The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Belongs to the DEAD box helicase family. DDX20 subfamily.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
  • Cellular localization

    Cytoplasm. Nucleus > gem. Localized in subnuclear structures next to coiled bodies, called Gemini of Cajal bodies.
  • Information by UniProt
  • Database links

  • Alternative names

    • Component of gems 3 antibody
    • DDX 20 antibody
    • ddx20 antibody
    • DDX20_HUMAN antibody
    • DEAD (Asp Glu Ala Asp) box polypeptide 20 antibody
    • DEAD box protein 20 antibody
    • DEAD box protein DP 103 antibody
    • DEAD box protein DP103 antibody
    • DEAD/H (Asp Glu Ala Asp/His) box polypeptide 20 103kD antibody
    • DEAD/H (Asp Glu Ala Asp/His) box polypeptide 20 antibody
    • DEAD/H BOX 20 antibody
    • DKFZP434H052 antibody
    • DP 103 antibody
    • DP103 antibody
    • Gemin-3 antibody
    • Gemin3 antibody
    • Probable ATP dependent RNA helicase DDX20 antibody
    • Probable ATP-dependent RNA helicase ddx20 antibody
    • SMN interacting protein antibody
    see all

Images

  • All lanes : Anti-Gemin 3 antibody (ab189850) at 1/500 dilution

    Lane 1 : MCF7 cell extract
    Lane 2 : ES-2 cell extract
    Lane 3 : 293T cell extract
    Lane 4 : HepG2 cell extract
    Lane 5 : HeLa cell extract
    Lane 6 : Mouse spleen extract
    Lane 7 : Rat testis extract
    Lane 8 : Mouse ovary extract

    Predicted band size: 92 kDa

References

ab189850 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab189850.
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