Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferConstituent: PBS
Concentration information loading...
PurityProtein A purified
Light chain typekappa
Our Abpromise guarantee covers the use of ab46778 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent dilution. Predicted molecular weight: 29 kDa.|
|IP||Use at an assay dependent dilution.|
|ICC/IF||Use at an assay dependent dilution.|
RelevanceGemin 8 forms a large macromolecular complex which includes other gemin proteins, SMN (survival motor neuron) protein and Unrip. This complex is required for assembly of small nuclear ribonucleoproteins (snRNPs) from Sm proteins and snRNAs. Gemin 8 mediates the binding of SMN with gemin 6 and gemin 7.
Cellular localizationCytoplasmic and Nuclear
- FAM51A1 antibody
- FLJ20514 antibody
- FLJ43072 antibody
- gem (nuclear organelle) associated protein 8 antibody
This product has been referenced in:
- Carissimi C et al. Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly. J Biol Chem 281:8126-34 (2006). Read more (PubMed: 16434402) »
- Carissimi C et al. Gemin8 is required for the architecture and function of the survival motor neuron complex. J Biol Chem 281:37009-16 (2006). Read more (PubMed: 17023415) »