Product nameGenistein, Protein tyrosine kinase inhibitor
DescriptionProtein tyrosine kinase inhibitor. Anticancer agent.
Biological descriptionPhytoestrogen found in soy beans. Anticancer agent. Inihibits tyrosine protein kinase and DNA topoisomerase as well as possessing antioxidant and cell cycle inhibitor activity. Endocytosis inhibitor.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Receptors & Transporters
- Enzyme-Linked Receptors
- Receptor tyrosine kinases
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120112 has been referenced in 4 publications.
- Sobhy MMK et al. Impact of treatment with a Protein Tyrosine Kinase Inhibitor (Genistein) on acute and chronic experimental Schistosoma mansoni infection. Exp Parasitol 185:115-123 (2018). PubMed: 29331278
- Ardito F et al. In vitro study on anti-cancer properties of genistein in tongue cancer. Onco Targets Ther 10:5405-5415 (2017). PubMed: 29180873
- Valeri A et al. The soy phytoestrogens genistein and daidzein as neuroprotective agents against anoxia-glucopenia and reperfusion damage in rat urinary bladder. Pharmacol Res 66:309-16 (2012). PubMed: 22743170
- Jayagopal A et al. Hairpin DNA-functionalized gold colloids for the imaging of mRNA in live cells. J Am Chem Soc 132:9789-96 (2010). PubMed: 20586450