Key features and details
- Rabbit polyclonal to GFRA4
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-GFRA4 antibody
DescriptionRabbit polyclonal to GFRA4
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
- 293T cell lysate; Human gastric cancer tissue.
This product was previously labelled as Persephin receptor
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
Note: PBS without Mg2+ and Ca2+.
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab183077 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 32 kDa.|
|IHC-P||1/25 - 1/100.|
FunctionReceptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
Tissue specificityPredominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands.
Sequence similaritiesBelongs to the GDNFR family.
Cellular localizationSecreted and Cell membrane.
- Information by UniProt
- GDNF family receptor alpha 4 antibody
- GDNF family receptor alpha-4 antibody
- GDNF receptor alpha-4 antibody
Anti-GFRA4 antibody (ab183077) at 1/600 dilution + 293T cell lysate at 60 µg
Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
Developed using the ECL technique.
Predicted band size: 32 kDa
Exposure time: 30 seconds
Gel: 10% SDS-PAGE
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue labeling GFRA4 with ab183077 at 1/40 dilution, in the presence (right panel) or absence (left panel) of immunizing peptide.
ab183077 has not yet been referenced specifically in any publications.