Key features and details
- Rabbit polyclonal to Ghrelin (Biotin)
- Suitable for: ELISA, IP, RIA
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG
Product nameAnti-Ghrelin antibody (Biotin)
See all Ghrelin primary antibodies
DescriptionRabbit polyclonal to Ghrelin (Biotin)
Tested applicationsSuitable for: ELISA, IP, RIAmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cat, Dog, Pig, Baboon, Rhesus monkey, Gerbil
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.50
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityProtein G purified
Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of ab48285 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent concentration.|
|IP||Use at an assay dependent concentration.|
|RIA||Use a concentration of 2 - 8 µg/ml.|
FunctionGhrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
Tissue specificityHighest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy.
Sequence similaritiesBelongs to the motilin family.
modificationsO-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28-C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28-C10:1, may be modified with a singly unsaturated carboxylic acid.
Amidation of Leu-98 is essential for obestatin activity.
- Information by UniProt
- Appetite regulating hormone antibody
- Ghrelin 27 antibody
- Ghrelin 28 antibody
ab48285 has not yet been referenced specifically in any publications.