Overview

  • Product name

    Anti-Ghrelin Receptor/GHS-R antibody
    See all Ghrelin Receptor/GHS-R primary antibodies
  • Description

    Rabbit polyclonal to Ghrelin Receptor/GHS-R
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Monkey, Gorilla, Common marmoset
  • Immunogen

    Synthetic peptide corresponding to Human Ghrelin Receptor/GHS-R (N terminal).
    Database link: Q92847

  • Positive control

    • IHC: Human pituitary, anterior tissue.
  • General notes

    Previously labelled as Ghrelin Receptor. 

Properties

Applications

Our Abpromise guarantee covers the use of ab150514 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 - 7.5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).
  • Tissue specificity

    Pituitary and hypothalamus.
  • Involvement in disease

    Defects in GHSR may be a cause of idiopathic short stature autosomal (ISSA) [MIM:604271]. Short stature is defined by a subnormal rate of growth.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • GH releasing peptide receptor antibody
    • GH-releasing peptide receptor antibody
    • Ghrelin receptor antibody
    • GHRP antibody
    • GHRPR antibody
    • GHS-R antibody
    • GHSR antibody
    • GHSR_HUMAN antibody
    • Growth hormone secretagogue receptor 1 antibody
    • Growth hormone secretagogue receptor type 1 antibody
    • growth hormone secretatgogue receptor antibody
    see all

Images

  • Immunohistochemistry of formalin-fixed, paraffin-embedded Human pituitary anterior tissue labelling Ghrelin Receptor/GHS-R with ab150514 at 5 µg/ml.

References

ab150514 has not yet been referenced specifically in any publications.

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