Anti-Ghrelin Receptor/GHS-R antibody (ab188986)
Key features and details
- Rabbit polyclonal to Ghrelin Receptor/GHS-R
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Ghrelin Receptor/GHS-R antibody
See all Ghrelin Receptor/GHS-R primary antibodies -
Description
Rabbit polyclonal to Ghrelin Receptor/GHS-R -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Hamster, Cow, Dog, Pig, Xenopus laevis, Monkey, Gorilla, Common marmoset, Xenopus tropicalis -
Immunogen
Synthetic peptide within Human Ghrelin Receptor/GHS-R (internal sequence). The exact sequence is proprietary. synthetic 16 amino acid peptide from internal region
Database link: Q92847 -
Positive control
- Human skin, hair follicle tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab188986 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use a concentration of 1 - 3 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 1 - 3 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). -
Tissue specificity
Pituitary and hypothalamus. -
Involvement in disease
Defects in GHSR may be a cause of idiopathic short stature autosomal (ISSA) [MIM:604271]. Short stature is defined by a subnormal rate of growth. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 514203 Cow
- Entrez Gene: 100101479 Dog
- Entrez Gene: 101129513 Gorilla
- Entrez Gene: 100731433 Guinea pig
- Entrez Gene: 100057865 Horse
- Entrez Gene: 2693 Human
- Entrez Gene: 208188 Mouse
- Entrez Gene: 397372 Pig
see all -
Alternative names
- GH releasing peptide receptor antibody
- GH-releasing peptide receptor antibody
- Ghrelin receptor antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab188986 has not yet been referenced specifically in any publications.