Overview

  • Product name
    Gilvocarcin V, Antibiotic agent
  • Description
    Antibiotic, antitumor agent
  • Biological description
    Antibiotic, antitumor agent. Chrysomycin B (ab144224) analog. Inhibits topoisomerase II. Photosensitizes DNA. Strongly active against Gram-positive bacteria. Weakly active against Gram-negative bacteria. Shows antifungal and antiviral effects. Shows antitumor effects in vivo.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Lytle CD  et al. Herpes virus infection and repair in cells pretreated with gilvocarcin V or merocyanine 540 and radiation. J Photochem Photobiol B 23:57-62 (1994). Read more (PubMed: 8021752) »
  • Peak MJ  et al. Photosensitized DNA breaks and DNA-to-protein crosslinks induced in human cells by antitumor agent gilvocarcin V. Chem Biol Interact 67:267-74 (1988). Read more (PubMed: 3191537) »
  • Weiss U  et al. The chemistry of the antibiotics chrysomycin A and B. Antitumor activity of chrysomycin A. J Antibiot (Tokyo) 35:1194-201 (1982). Read more (PubMed: 7142022) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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