Ginkgolide A, platelet -activating factor (PAF) antagonist (ab142602)

Overview

  • Product name

    Ginkgolide A, platelet -activating factor (PAF) antagonist
  • Description

    Highly active platelet -activating factor (PAF) antagonist
  • Biological description

    Highly active platelet -activating factor (PAF) antagonist. Biologically active terpinoid. Anti-inflammatory effects in vivo.
  • Purity

    > 95%
  • CAS Number

    15291-75-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (1R,3R,8S,10R,13S,16S,17R)-8-tert-Butyl-6,17-dihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione
  • Molecular weight

    480.40
  • Molecular formula

    C20H24O9
  • PubChem identifier

    441293
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C[C@@H]1C(=O)O[C@@H]2[C@]1([C@@]34C(=O)O[C@H]5C3(C2)C6([C@@H](C5)C(C)(C)C)[C@H](O4)OC(=O)C6O)O
  • Source

    Ginkgo biloba

  • Research areas

References

This product has been referenced in:

  • Singh P  et al. Platelet-activating factor (PAF)-antagonists of natural origin. Fitoterapia 84:180-201 (2013). Read more (PubMed: 23160091) »
  • Xie J  et al. Simultaneous determination of ginkgolides A, B, C and bilobalide in plasma by LC-MS/MS and its application to the pharmacokinetic study of Ginkgo biloba extract in rats. J Chromatogr B Analyt Technol Biomed Life Sci 864:87-94 (2008). Read more (PubMed: 18295555) »
  • Wada K  et al. Isolation of bilobalide and ginkgolide A from Ginkgo biloba L. shorten the sleeping time induced in mice by anesthetics. Biol Pharm Bull 16:210-2 (1993). Read more (PubMed: 8364459) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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