Anti-GIRK-3 antibody (ab134807)
Key features and details
- Rabbit polyclonal to GIRK-3
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GIRK-3 antibody -
Description
Rabbit polyclonal to GIRK-3 -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species IHC-P HumanWB Human
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Immunogen
Synthetic peptide corresponding to Human GIRK-3 (internal sequence).
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Positive control
- IHC-P: Human Brain, Cortex Neurons tissue; WB: LOVO cell extracts.
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General notes
Previously labelled as KCNJ9.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride
PBS (without Mg2+, Ca2+) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab134807 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| IHC-P |
Human
|
| WB |
Human
|
| All applications |
Mouse
Rat
|
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 44 kDa.
|
|
| IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
| Notes |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 44 kDa. |
|
IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. -
Sequence similarities
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ9 subfamily. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 3765 Human
- Entrez Gene: 16524 Mouse
- Entrez Gene: 116560 Rat
- Omim: 600932 Human
- SwissProt: Q92806 Human
- SwissProt: P48543 Mouse
- SwissProt: Q63511 Rat
- Unigene: 66726 Human
see all -
Alternative names
- G protein activated inward rectifier potassium channel 3 antibody
- G protein coupled inward rectifier potassium channel antibody
- G protein-activated inward rectifier potassium channel 3 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GIRK-3 antibody (ab134807)
Immunohistochemistry analysis of Formalin fixed and Paraffin Embedded (IHC-P) Human Brain, Cortex Neurons tissue labelling GIRK-3 with ab134807 at 5 µg/ml.
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Western blot - Anti-GIRK-3 antibody (ab134807)All lanes : Anti-GIRK-3 antibody (ab134807) at 1/500 dilution
Lane 1 : Protein extract from Lovo cells
Lane 2 : Protein extract from Lovo cells, treated with the synthesized peptide
Predicted band size: 44 kDa
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab134807 has not yet been referenced specifically in any publications.