Overview

  • Product name

  • Description

    Rabbit polyclonal to GIRK1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Dog, Human
  • Immunogen

    Synthetic peptide within Human GIRK1 aa 106-129 conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Sequence:

    AYTRGDLNKAHVGNYTPCVANVYN


    Database link: P48549

  • Positive control

    • Mouse kidney lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab204122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

(or 1/50 - 1/200 using a fluorescent secondary antibody).

WB 1/100 - 1/1000. Predicted molecular weight: 57 kDa.

Target

  • Function

    This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
  • Sequence similarities

    Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • G protein activated inward rectifier potassium channel 1 antibody
    • G protein-activated inward rectifier potassium channel 1 antibody
    • GIRK-1 antibody
    • GIRK1 antibody
    • Inward rectifier K(+) channel Kir3.1 antibody
    • Inwardly rectifying potassium channel KIR3.1 antibody
    • inwardly rectifying subfamily J member 3 antibody
    • IRK3 antibody
    • IRK3_HUMAN antibody
    • Kcnf3 antibody
    • Kcnj3 antibody
    • KGA antibody
    • KGB1 antibody
    • Kir3.1 antibody
    • Potassium channel antibody
    • Potassium channel, inwardly rectifying subfamily J member 3 antibody
    • Potassium inwardly-rectifying channel, subfamily J, member 3 antibody
    see all

Images

  • Anti-GIRK1 antibody (ab204122) at 1/300 dilution (incubated overnight at 4°C)
    Secondary
    Goat Anti-Rabbit IgG Antibody (H+L), HRP Conjugated (incubated 90min at 37°C) at 1/5000 dilution

    Predicted band size: 57 kDa

References

ab204122 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab204122.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up