Overview

  • Product name
    Anti-GITR antibody [CAL61]
    See all GITR primary antibodies
  • Description
    Rabbit monoclonal [CAL61] to GITR
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Mouse GITR aa 175-228.
    Database link: O35714

  • Positive control
    • IHC-P: Mouse spleen tissue.
  • General notes

     This product was previously labelled as TNFRSF18

     

Properties

Applications

Our Abpromise guarantee covers the use of ab237725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 0.125 µg/ml.

Boil tissue section in citrate buffer for 24 minutes followed by cooling at room temperature for 30-45 minutes. Incubate with primary antibody for 75 minutes at room temperature. Slides must be washed in between steps. Rinse slides with TBS/0.05% Tween.

Target

  • Function
    Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
  • Tissue specificity
    Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
  • Sequence similarities
    Contains 3 TNFR-Cys repeats.
  • Cellular localization
    Secreted and Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activation inducible TNFR family receptor antibody
    • Activation-inducible TNFR family receptor antibody
    • AITR antibody
    • CD357 antibody
    • GITR antibody
    • GITR D antibody
    • GITR-D antibody
    • GITRD antibody
    • Glucocorticoid induced TNFR related protein antibody
    • glucocorticoid-induced tnf receptor ligand antibody
    • glucocorticoid-induced tnf receptors ligand antibody
    • Glucocorticoid-induced TNFR-related protein antibody
    • TNF receptor superfamily activation inducible protein antibody
    • TNFRSF 18 antibody
    • TNFRSF18 antibody
    • TNR18_HUMAN antibody
    • Tumor necrosis factor receptor superfamily member 18 antibody
    • Tumor necrosis factor receptor superfamily member 18 precursor antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded mouse spleen tissue stained for GITR using ab237725 at 0.125 µg/ml dilution in immunohistochemical analysis.

References

ab237725 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab237725.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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