Overview

  • Product name

    Anti-GITR antibody [DTA-1] (FITC)
    See all GITR primary antibodies
  • Description

    Rat monoclonal [DTA-1] to GITR (FITC)
  • Host species

    Rat
  • Conjugation

    FITC. Ex: 493nm, Em: 528nm
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    Tissue, cells or virus corresponding to TNFSF18/GITRL. Mouse CD25+ CD4+ T cell line.

  • Positive control

    • Flow Cyt: Mouse splenocytes.
  • General notes

    Protein previously known as TNFSF18.

Properties

Applications

Our Abpromise guarantee covers the use of ab72404 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

ab136125 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

Target

  • Function

    Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
  • Tissue specificity

    Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
  • Sequence similarities

    Contains 3 TNFR-Cys repeats.
  • Cellular localization

    Secreted and Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Activation inducible TNFR family receptor antibody
    • Activation-inducible TNFR family receptor antibody
    • AITR antibody
    • CD357 antibody
    • GITR antibody
    • GITR D antibody
    • GITR-D antibody
    • GITRD antibody
    • Glucocorticoid induced TNFR related protein antibody
    • glucocorticoid-induced tnf receptor ligand antibody
    • glucocorticoid-induced tnf receptors ligand antibody
    • Glucocorticoid-induced TNFR-related protein antibody
    • TNF receptor superfamily activation inducible protein antibody
    • TNFRSF 18 antibody
    • TNFRSF18 antibody
    • TNR18_HUMAN antibody
    • Tumor necrosis factor receptor superfamily member 18 antibody
    • Tumor necrosis factor receptor superfamily member 18 precursor antibody
    see all

Images

  • C57Bl/6 splenocytes stained with PE-conjugated anti-mouse CD4, APC-conjugated anti-mouse CD25 and 0.06 µg ab72404.

    Cells in the CD4+ lymphocyte gate are shown.

References

ab72404 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab72404.
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