Overview

  • Product name

    Glabridin, Antiproliferative agent
  • Description

    Antiproliferative agent
  • Biological description

    Antiproliferative agent. Inhibits melanogenesis. Induces apoptosis through caspase 3, 8, and 9 activation and PARP cleavage. Activates ERK1/2, p38 MAPK and JNK1/2. Shows estrogenic, neuroprotective, depigmenting and antitumor effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    59870-68-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Hsieh MJ  et al. Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase 9 through modulation of NF-?B and AP-1 activity in human liver cancer cells. Br J Pharmacol 171:3037-50 (2014). Read more (PubMed: 24641665) »
  • Huang HL  et al. Glabridin Mediate Caspases Activation and Induces Apoptosis through JNK1/2 and p38 MAPK Pathway in Human Promyelocytic Leukemia Cells. PLoS One 9:e98943 (2014). Read more (PubMed: 24901249) »
  • Yokota T  et al. The inhibitory effect of glabridin from licorice extracts on melanogenesis and inflammation. Pigment Cell Res 11:355-61 (1998). Read more (PubMed: 9870547) »
See 1 Publication for this product

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