Overview

  • Product name

    Anti-Gli1 antibody [EPR4523] - BSA and Azide free
    See all Gli1 primary antibodies
  • Description

    Rabbit monoclonal [EPR4523] to Gli1 - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Gli1 aa 1-100. The exact sequence is proprietary.

  • General notes

    ab240088 is the carrier-free version of ab134906 This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    Ab240088 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    This antibody was developed as part of a collaboration with the lab of Martin Fernandez-Zapico at the Mayo Clinic. Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab240088 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 118 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function

      Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
    • Tissue specificity

      Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve and olfactory tract.
    • Sequence similarities

      Belongs to the GLI C2H2-type zinc-finger protein family.
      Contains 5 C2H2-type zinc fingers.
    • Post-translational
      modifications

      Phosphorylated in vitro by ULK3.
    • Cellular localization

      Cytoplasm. Nucleus. Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1.
    • Information by UniProt
    • Database links

    • Alternative names

      • Gli 1 antibody
      • GLI antibody
      • GLI family zinc finger 1 antibody
      • GLI Kruppel family member 1 antibody
      • gli1 antibody
      • GLI1_HUMAN antibody
      • Glioma associated oncogene 1 antibody
      • Glioma associated oncogene homolog 1 (zinc finger protein) antibody
      • Glioma associated oncogene homolog antibody
      • Glioma-associated oncogene antibody
      • Oncogene GLI antibody
      • Zfp 5 antibody
      • Zfp5 antibody
      • Zinc finger protein GLI 1 antibody
      • Zinc finger protein GLI1 antibody
      see all

    References

    ab240088 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab240088.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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