Product nameGlipizide, Sulfonylurea receptor
DescriptionSulfonylurea receptor and ATP-sensitive K+ channel blocker
Biological descriptionSulfonylurea receptor and ATP-sensitive K+ channel blocker. Highly potent insulinotropic agent (ED50 = 40 pM). Sulfonylurea and hypoglycemic agent. Active in vivo and in vitro. Orally active.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Receptors & Transporters
- Enzyme-Linked Receptors
- Receptor tyrosine kinases
This product has been referenced in:
- Ocaña M et al. ATP-dependent K+ channel blockers antagonize morphine- but not U-504,88H-induced antinociception. Eur J Pharmacol 230:203-7 (1993). Read more (PubMed: 8422902) »
- Boyd AE Sulfonylurea receptors, ion channels, and fruit flies. Diabetes 37:847-50 (1988). Read more (PubMed: 2454858) »
- Herchuelz A & Malaisse WJ Insulinotropic potency of glipizide in vitro. Diabetologia :309-10 (1973). Read more (PubMed: 4772977) »