Product nameGlucagon (human), Endogenous peptide hormone
DescriptionEndogenous peptide hormone and potent glucagon receptor agonist
Biological descriptionEndogenous peptide hormone and potent glucagon receptor agonist (EC50 = 4.8 nM). Promotes gluconeogenesis and glycogenolysis to increase blood glucose levels. Hyperglycemic agent.
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in 5% acetic acid
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Receptors & Transporters
- Peptide Receptors
- Glucagon and Related Receptors
This product has been referenced in:
- Cryer PE Minireview: Glucagon in the pathogenesis of hypoglycemia and hyperglycemia in diabetes. Endocrinology 153:1039-48 (2012). Read more (PubMed: 22166985) »
- Cypess AM et al. Two cytoplasmic loops of the glucagon receptor are required to elevate cAMP or intracellular calcium. J Biol Chem 274:19455-64 (1999). Read more (PubMed: 10383462) »
- Weinges KF et al. The immunological reactivity and biological activity of synthetic glucagon. Diabetologia 5:97-100 (1969). Read more (PubMed: 5392908) »